Patents by Inventor Richard J. Epstein

Richard J. Epstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activation-state-specific phosphoprotein immunodetection
    Patent number: 5599681
    Abstract: Activation-state-specific and protein-specific antiphosphoprotein antibodies and methods for their production are disclosed. Also disclosed are methods for evaluating the prognosis and therapeutic outcome for patients using the antiphosphoprotein antibodies and methods for characterizing the activation state of a reversibly phosphorylated protein, kits including the antibodies for use in characterizing the activation state of a protein, and methods for evaluating the agonist or antagonist activity of pharmaceutically useful compounds towards the conversion of a specific protein from its inactive to its active state.
    Type: Grant
    Filed: October 13, 1994
    Date of Patent: February 4, 1997
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Richard J. Epstein, Charles D. Stiles