Patents by Inventor Richard J. Gumina

Richard J. Gumina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic use of platelet-endothelial cell adhesion molecule-1 compositions
    Patent number: 6087331
    Abstract: Novel, substantially isolated isoforms of human platelet-endothelial cell adhesion molecule-1's, DNAs coding for transcripts that encode the novel isoforms and others, including a previously identified soluble isoform, methods of using such DNAs to make isoforms by expressing the DNA's, and promoter segments controlling transcription of human platelet-endothelial cell adhesion molecule-1 genes are provided. The novel isoforms differ from the complete human platelet-endothelial cell adhesion molecule-1's in lacking one or more segments near the C-terminus encoded by exons 10-15 of the genes for the full length molecules and arise in vivo from alternative splicing of the transcript from the genes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 11, 2000
    Assignee: The Blood Center of Southeastern Wisconsin
    Inventors: Peter J. Newman, Richard J. Gumina, Nancy Kirshbaum
  • Platelet endothelial cell adhesion molecule-1 promoters and uses thereof
    Patent number: 5668012
    Abstract: Novel, substantially isolated isoforms of human platelet-endothelial cell adhesion molecule-1's, DNAs coding for transcripts that encode the novel isoforms and others, including a previously identified soluble isoform, methods of using such DNAs to make isoforms by expressing the DNA's, and promoter segments controlling transcription of human platelet-endothelial cell adhesion molecule-1 genes are provided. The novel isoforms differ from the complete human platelet-endothelial cell adhesion molecule-1's in lacking one or more segments near the C-terminus encoded by exons 10-15 of the genes for the full length molecules and arise in vivo from alternative splicing of the transcript from the genes.
    Type: Grant
    Filed: July 5, 1994
    Date of Patent: September 16, 1997
    Assignee: The Blood Center Research Foundation, Inc.
    Inventors: Peter J. Newman, Richard J. Gumina, Nancy Kirshbaum