Patents by Inventor Richard J. H. Begent

Richard J. H. Begent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies against tumor surface antigens
    Patent number: 7626011
    Abstract: The present invention relates to improved antibodies against tumor surface antigens and their use in the treatment of tumors. Of particular interest are highly stable, humanized, high affinity antibodies against carcinoembryonic antigen (CEA), especially the antibody we have termed sm3E, which is derived from the scFv antibody MFE-23. Such antibodies have the potential for improved therapeutic efficacy.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: December 1, 2009
    Assignees: Cancer Research Technology Limited, Massachusetts Institute of Technology
    Inventors: Richard J. H. Begent, Kerry Ann Chester, Christilyn P. Graff, K. Dane Wittrup
  • Antibodies against tumor surface antigens
    Patent number: 7232888
    Abstract: The present invention relates to improved antibodies against tumor surface antigens and their use in the treatment of tumors. Of particular interest are highly stable, humanized, high affinity antibodies against carcinoembryonic antigen (CEA), especially the antibody we have termed sm3E, which is derived from the scFv antibody MFE-23. Such antibodies have the potential for improved therapeutic efficacy.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: June 19, 2007
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard J. H. Begent, Kerry Ann Chester, Christilyn P. Graff, K. Dane Wittrup