Patents by Inventor Richard J. H. Smith

Richard J. H. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to prevent and treat autosomal dominant non-syndromic hearing loss
    Patent number: 9758781
    Abstract: The present invention provides in certain embodiments a method of treating autosomal dominant non-syndromic hearing loss (ADNSHL) in a patient in need thereof comprising: (a) identifying a mutation in an ADNSHL-causing gene, (b) preparing a ADNSHL therapeutic miRNA, and (c) administering to the patient a pharmaceutical composition comprising the ADNSHL therapeutic miRNA and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: September 12, 2017
    Assignee: University of Iowa Research Foundation
    Inventors: Richard J. H. Smith, Seiji Shibata
  • Treatment of chronic nephropathies using soluble complement receptor type I (sCR1)
    Patent number: 9649357
    Abstract: A method is disclosed for treating nephropathies involving undesired alternative pathway complement activation by administration of a complement inhibitory protein such as soluble complement receptor type I (sCR1).
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: May 16, 2017
    Assignees: CELLDEX THERAPEUTICS, INC., UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Richard J. H. Smith, Yuzhou Zhang, Henry C. Marsh
  • Treatment Of Chronic Nephropathies Using Soluble Complement Receptor Type I (sCR1)
    Publication number: 20160184392
    Abstract: A method is disclosed for treating nephropathies involving undesired alternative pathway complement activation by administration of a complement inhibitory protein such as soluble complement receptor type I (sCR1).
    Type: Application
    Filed: March 16, 2016
    Publication date: June 30, 2016
    Inventors: Richard J.H. SMITH, Yuzhou ZHANG, Henry C. MARSH
  • METHODS TO PREVENT AND TREAT AUTOSOMAL DOMINANT NON-SYNDROMIC HEARING LOSS
    Publication number: 20160090597
    Abstract: The present invention provides in certain embodiments a method of treating autosomal dominant non-syndromic hearing loss (ADNSHL) in a patient in need thereof comprising: (a) identifying a mutation in an ADNSHL-causing gene, (b) preparing a ADNSHL therapeutic miRNA, and (c) administering to the patient a pharmaceutical composition comprising the ADNSHL therapeutic miRNA and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: September 10, 2015
    Publication date: March 31, 2016
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Richard J.H. Smith, Seiji Shibata
  • Treatment of chronic nephropathies using soluble complement receptor type I (sCR1)
    Patent number: 9295713
    Abstract: A method is disclosed for treating nephropathies involving undesired alternative pathway complement activation by administration of a complement inhibitory protein such as soluble complement receptor type I (sCR1).
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: March 29, 2016
    Assignees: CELLDEX THERAPEUTICS, INC., UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Richard J. H. Smith, Yuzhou Zhang, Henry C. Marsh
  • TREATMENT OF CHRONIC NEPHROPATHIES USING SOLUBLE COMPLEMENT RECEPTOR TYPE I (sCR1)
    Publication number: 20120071413
    Abstract: A method is disclosed for treating nephropathies involving undesired alternative pathway complement activation by administration of a complement inhibitory protein such as soluble complement receptor type I (sCR1).
    Type: Application
    Filed: September 15, 2011
    Publication date: March 22, 2012
    Inventors: Richard J. H. Smith, Yuzhou Zhang, Henry C. Marsh