Patents by Inventor Richard J. O'Reilly

Richard J. O'Reilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Selecting T Cell Line and Donor Thereof for Adoptive Cellular Therapy
    Publication number: 20220023417
    Abstract: Disclosed herein are methods of selecting an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. Also disclosed are methods of selecting a donor from whom to derive an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer.
    Type: Application
    Filed: October 8, 2021
    Publication date: January 27, 2022
    Applicant: Memorial Sloan Kettering Cancer Center
    Inventors: Richard J. O'Reilly, Ekaterina Doubrovina, Guenther Koehne, Aisha N. Hasan, Susan E. Prockop
  • Methods of selecting T cell line and donor thereof for adoptive cellular therapy
    Patent number: 11173205
    Abstract: Disclosed herein are methods of selecting an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. Also disclosed are methods of selecting a donor from whom to derive an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: November 16, 2021
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Richard J. O'Reilly, Ekaterina Doubrovina, Guenther Koehne, Aisha N. Hasan, Susan E. Prockop
  • Immunogenic WT-1 peptides and methods of use thereof
    Patent number: 10100087
    Abstract: This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT-1-expressing cancer, comprising peptides derived from the WT-1 protein.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: October 16, 2018
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Richard J. O'Reilly, Ekaterina Doubrovina, Annamalai Selvakumar
  • IMMUNOGENIC WT-1 PEPTIDES AND METHODS OF USE THEREOF
    Publication number: 20170334951
    Abstract: This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT-1-expressing cancer, comprising peptides derived from the WT-1 protein.
    Type: Application
    Filed: May 30, 2017
    Publication date: November 23, 2017
    Applicant: Memorial Sloan Kettering Cancer Center
    Inventors: Richard J. O'Reilly, Ekaterina Doubrovina, Annamalai Selvakumar
  • Methods of Selecting T cell Line and Donor Thereof for Adoptive Cellular Therapy
    Publication number: 20170319683
    Abstract: Disclosed herein are methods of selecting an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. Also disclosed are methods of selecting a donor from whom to derive an allogeneic T cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer.
    Type: Application
    Filed: November 4, 2015
    Publication date: November 9, 2017
    Applicant: Memorial Sloan Kettering Cancer Center
    Inventors: Richard J. O'Reilly, Ekaterina Doubrovina, Guenther Koehne, Aisha N. Hasan, Susan E. Prockop
  • ANTIGEN-BINDING PROTEINS SPECIFIC FOR HLA-A2-RESTRICTED WILMS TUMOR 1 PEPTIDE
    Publication number: 20160152725
    Abstract: Antigen-binding proteins specific for HLA-A2-restricted Wilms tumor 1 peptide are disclosed. The antigen-binding proteins encompass antibodies in a variety of forms, including full-length antibodies, substantially intact antibodies, Fab fragments, F(ab?)2 fragments, and single chain Fv (scFv) fragments, as well as chimeric antigen receptors. Fusion proteins, such as scFv fusions with immunoglobulin or T-cell receptor domains, incorporating the antigen-binding proteins are provided. Methods of using the antigen-binding proteins in the treatment of hyperproliferative diseases such as cancer are also disclosed.
    Type: Application
    Filed: February 25, 2015
    Publication date: June 2, 2016
    Inventors: Nai-Kong V. Cheung, Mahiuddin Ahmed, Richard J. O'Reilly, Dimiter V. Tassev, Qi Zhao
  • IMMUNOGENIC WT-1 PEPTIDES AND METHODS OF USE THEREOF
    Publication number: 20150104413
    Abstract: This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT-1-expressing cancer, comprising peptides derived from the WT-1 protein.
    Type: Application
    Filed: January 14, 2013
    Publication date: April 16, 2015
    Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Richard J. O'Reilly, Ekaterina Doubrovina, Annamalai Selvakumar