Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin or digoxin is used to treat the viral infection or the disease state of said viral infection.

Abstract: A subcritical liquid extraction process for the production of oleandrin or oleandrin-containing extract is provided. The process provides improvements over other methods of preparing oleandrin-containing extract. The extract, pharmaceutical compositions, dosage forms and nutraceutical compositions comprising oleandrin or said extract are provided. Methods of treating diseases, disorders or conditions that are therapeutically responsive to oleandrin are also provided.

Abstract: A method of treating viral infection, such as viral infection caused by a virus of the Coronaviridae family, is provided. A composition having at least oleandrin or digoxin is used to treat the viral infection or the disease state of said viral infection.

Abstract: This invention relates to a process for detecting the presence of viable bacterial spores in a sample and to a spore detection system, the process including placing a sample in a germination medium for a period of time sufficient for commitment of any present viable bacterial spores to occur, mixing the sample with a solution of a lanthanide capable of forming a fluorescent complex with dipicolinic acid, and, measuring the sample for the presence of dipicolinic acid, and the system including a germination chamber having inlets from a sample chamber, a germinant chamber and a bleach chamber, the germination chamber further including an outlet through a filtering means, the outlet connected to a detection chamber, the detection chamber having an inlet from a fluorescence promoting metal chamber and the detection chamber including a spectral excitation source and a means of measuring emission spectra from a sample, the detection chamber further connected to a waste chamber.

Abstract: A method is described for the detection, either qualitatively or quantitatively, of gastrointestinal microorganisms in samples, preferably fecal samples, using immunoassays, preferably electrochemiluminescence (ECL) immunoassays. The methods involve detection without the conventional processing steps typically required for such detection (e.g., lysing, enrichment, separation, or purification). The method comprises dilution of the sample thought to contain a specific microorganism, inactivation (e.g., heat inactivation) of the diluted sample, removal of solids from the inactivated diluted sample, and detection of the pathogen in the inactivated diluted sample, by conducting an electrochemiluminescence assay for a bound complex of antibody and antigenic derivative, thereby detecting and/or presumptively identifying the microorganism in the sample.