Abstract: The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a pen type drug delivery device and to such a drug delivery device. The mechanism comprises a spring driven rotatable drive member, a rotatable driven member, a clutch rotationally coupling the driven member and the drive member in a coupled state and allowing relative clockwise and anti-clockwise rotation between the driven member and the drive member in a decoupled state, and a spring biasing the clutch into its coupled state and allowing relative axial movement between the drive member and the driven member into the decoupled state of the clutch against the bias of the spring.

Abstract: The present invention relates to a drug delivery device (6) comprising a dose button (1). Furthermore it relates to a method for manufacturing a dose button (1) by using a cutting-off process. The aim of the present invention is to minimize the risk of using a drug delivery device (6) containing a wrong drug. By means of tactile features, a drug delivery device (6) is distinguishable from another drug delivery device (6) containing another type of drug. This tactile feature is manufactured by using a dose button (1) out of metal which is milled or lathed.

Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament comprising a clicker arrangement. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) coupled to the dose selector (80) and arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10), a clutch (120) arranged between the number sleeve (60) and the drive sleeve (40), and a dispense clicker comprising a flexible arm (123) and a toothed profile (75). The device further comprises a button (70) operable to effect dose dispensing.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (10), a dose selector (80) operable to set a dose by rotation relative to the housing (10), a number sleeve (60) arranged within the housing (10) such that at least a portion of the number sleeve (60) is visible through a first aperture (11b) in the housing (10), a piston rod (30) coupled to the housing (10) and to a drive sleeve (40) such that rotation of the drive sleeve (40) relative to the housing (10) causes the piston rod (30) to translate relative to the housing (10) and a clutch mechanism arranged between the number sleeve (60) and the drive sleeve (40).

Abstract: A set of members for a drug delivery device comprises at least two components for the device, wherein both components are provided with a marking, the markings being substantially equivalent or identical. Furthermore, a drug delivery device and a set of drug delivery devices are provided.

Abstract: A coded collapsible drug reservoir and a drug delivery system including the coded collapsible drug reservoir. The drug reservoir includes a collapsible housing and a port in communication with the collapsible housing. The drug reservoir further includes a coding feature disposed on the drug reservoir, and the coding feature identifies the drug reservoir.

Abstract: A dose setting mechanism having a locking mechanism for preventing selection of a dose in a drug delivery device is disclosed. The dose setting mechanism includes a locking mechanism that prevents movement of the dose setting mechanism. When a correct cartridge is inserted into the drug delivery device, the locking mechanism unlocks so as to allow movement of the dose setting mechanism. In one arrangement, the locking mechanism prevents rotation of the dose setting mechanism.

Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Abstract: A coded collapsible drug reservoir and a drug delivery system including the coded collapsible drug reservoir. The drug reservoir includes a collapsible housing and a port in communication with the collapsible housing. The drug reservoir further includes a coding feature disposed on the drug reservoir, and the coding feature identifies the drug reservoir.

Abstract: A coding system for a drug reservoir, where the drug reservoir is intended for use with a reservoir holder of a drug delivery device. The coding system includes a collar fitted around the drug reservoir. The collar includes a coding feature that is configured to pass through a corresponding coding feature provided by the reservoir holder of the drug delivery device.

Abstract: A coding system for a drug reservoir, where the drug reservoir is intended for use with a reservoir holder of a drug delivery device. The coding system includes a collar fitted around the drug reservoir. The collar includes a coding feature that is configured to pass through a corresponding coding feature provided by the reservoir holder of the drug delivery device.

Abstract: This disclosure refers to a dosing mechanism for use in a drug delivery device implementing a dialing mode and a dispensing mode, wherein the dosing mechanism comprises a dose button, a housing and a determination unit. The dose button is activatable by the user for dose dispense, causing displacement of an indicating element connected to the housing from a first position to a second position. The determination unit is adapted such that it detects the indicating element in its second position and thereby determines that the dosing mechanism is in the dispensing mode. With some embodiments, it is possible to distinguish between the dialing mode and the dispensing mode. Some embodiments further refer to a drug delivery device comprising the above dosing mechanism.

Abstract: A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when said medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.

Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.

Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing.

Abstract: The disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing having a proximal end and an opposite distal end, a dose setting member rotatable relative to the housing during dose setting and during dose dispensing, and an axially compressible torsion spring which is rotationally and axially constrained with a first end to the housing. The device further comprises a spring collar, which is rotationally constrained to the dose setting member and axially displaceable thereto between a proximal dose setting position and a distal dose dispensing position. The torsion spring is rotationally constrained with a second, opposite end to the dose setting member via the spring collar, and the torsion spring biases the spring collar into its dose setting position.

Abstract: The present disclosure is generally directed to a trigger mechanism for initiating dispensing doses of a medicament from a drug delivery device. The trigger mechanism includes a trigger element movable in a first direction relative to a counter element. To provide a feedback to a user of the trigger mechanism, the trigger element includes a first interference member and the counter element includes a second interference member located with respect to the first interference member such that upon movement of the trigger element relative to the counter element the first interference member contacts and passes over the second interference member, thereby generating an audible and/or tactile feedback. Further, the disclosure includes a drug delivery device for selecting and dispensing a number of user variable doses of a medicament comprising such a trigger mechanism.

Abstract: A method and system for detecting information related to a drug reservoir. The method includes transmitting energy at a coded material disposed on a drug reservoir, where the energy has at least one predefined characteristic. The coded material identifies information related to the drug reservoir. The coded material modifies the energy and emits the modified energy to a receiver. The method further includes receiving at the receiver the modified energy. The method further includes determining information related to the drug reservoir based on the modified energy as the drug reservoir is loaded into a drug delivery device.

Abstract: A locking mechanism is provided for use with a reservoir and a reservoir holder so as to prevent unwanted tampering with the reservoir. The mechanism comprises a main body with an aperture that is coupled to the reservoir. A hinged flange is provided on the main body. The flange folds inwards at the pivot point provided by the hinge, toward the aperture of the main body, allowing the mechanism to pass over the ferrule of the reservoir. Once the mechanism is placed over the cartridge, the flange folds toward the reservoir at the pivot point, flexing away from the main body. The flange rests against the underside of the reservoir ferrule, thereby retaining the reservoir within the locking mechanism. The locking mechanism may be for use with either a disposable or a reusable delivery device.