Patents by Inventor Richard Jin
Richard Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240117030Abstract: The present invention relates to antibodies that specifically bind to one or more of IL-4, IL-13, IL-33, TSLP, and p40. The present invention further relates to antibodies that bind to one of IL-4, IL-13, IL-33, or TSLP. The invention further relates to multispecific antibodies that specifically bind to IL-4 and IL-13, and at least one other target. The present invention relates to multispecific antibodies that bind IL-4, IL-13, and one of IL-33, TSLP, or p40. The present invention also pertains to related molecules, e.g. nucleic acids which encode such antibodies or multispecific antibodies, compositions, and related methods, e.g., methods for producing and purifying such antibodies and multispecific antibodies, and their use in diagnostics and therapeutics.Type: ApplicationFiled: February 28, 2023Publication date: April 11, 2024Inventors: Rita Diane AGOSTINELLI, James Reasoner APGAR, Eric Matthew BENNETT, Laird BLOOM, Ting CHEN, Aaron Michael D'ANTONA, Arnab DE, Fang JIN, Marion Teresa KASAIAN, Matthew Allister LAMBERT, Kimberly Ann MARQUETTE, Virginie MCMANUS, Jessica Haewon MIN DEBARTOLO, Nicole Melissa PICHE-NICHOLAS, Richard Thomas SHELDON, Lioudmila TCHISTIAKOVA, Alexander Michael Shuford BARRON, Richard Lee GIESECK, III, Xiaotian ZHONG
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Patent number: 11927712Abstract: Disclosed herein is a method for eccentricity correction. This method may dispose a downhole tool into a borehole. The downhole tool may comprise a measuring assembly that has at least one transducer, determining a beam pattern from the at least one transducer, determining a center of the measurement assembly in the borehole with the beam pattern, calculating a beam pattern factor with at least the beam pattern, calculating an angle factor with at least the beam pattern, calculating an eccentricity factor with at least the beam pattern factor and the angle factor, and creating an eccentricity corrected image with at least the eccentricity factor.Type: GrantFiled: May 16, 2022Date of Patent: March 12, 2024Assignee: Halliburton Energy Services, Inc.Inventors: Yu Weng, Peng Li, Chung Chang, Richard Coates, Rodney Allen Marlow, Xiang Wu, Yao Ge, Jing Jin
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Patent number: 11577450Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: GrantFiled: September 22, 2021Date of Patent: February 14, 2023Assignee: Organovo, Inc.Inventors: Keith Murphy, Scott Dorfman, Nathan Smith, Larry Bauwens, Ian Sohn, Tim McDonald, Chris Leigh-Lancaster, Richard Jin Law
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Patent number: 11577451Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: GrantFiled: September 23, 2021Date of Patent: February 14, 2023Assignee: Organovo, Inc.Inventors: Keith Murphy, Scott Dorfman, Nathan Smith, Larry Bauwens, Ian Sohn, Tim McDonald, Chris Leigh-Lancaster, Richard Jin Law
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Publication number: 20220333963Abstract: A sensor unit that is configured to improve the non-contact, magnetic interface on a gas meter. The configurations may include a pair of magnets that co-rotate in response to a magnet internal to the gas meter. At least one of the magnets may also move longitudinally in proximity to the internal magnet. This feature aligns the magnets with one another to ensure proper magnetic coupling with the internal magnet.Type: ApplicationFiled: April 4, 2022Publication date: October 20, 2022Inventors: Jeff Thomas Martin, Roman Leon Artiuch, Richard Jin Yao, Jeffrey Raynal
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Patent number: 11413805Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: GrantFiled: September 24, 2021Date of Patent: August 16, 2022Assignee: Organovo, Inc.Inventors: Keith Murphy, Scott Dorfman, Nathan Smith, Larry Bauwens, Ian Sohn, Tim McDonald, Chris Leigh-Lancaster, Richard Jin Law
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Patent number: 11293789Abstract: A sensor unit that is configured to improve the non-contact, magnetic interface on a gas meter. The configurations may include a pair of magnets that co-rotate in response to a magnet internal to the gas meter. At least one of the magnets may also move longitudinally in proximity to the internal magnet. This feature aligns the magnets with one another to ensure proper magnetic coupling with the internal magnet.Type: GrantFiled: December 18, 2019Date of Patent: April 5, 2022Assignee: Natural Gas Solutions North America, LLCInventors: Jeff Thomas Martin, Roman Leon Artiuch, Jeffrey Raynal, Richard Jin Yao
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Publication number: 20220009157Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: ApplicationFiled: September 23, 2021Publication date: January 13, 2022Applicant: ORGANOVO, INC.Inventors: Keith MURPHY, Scott DORFMAN, Nathan SMITH, Larry BAUWENS, Ian SOHN, Tim MCDONALD, Chris LEIGH-LANCASTER, Richard Jin LAW
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Publication number: 20220009158Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: ApplicationFiled: September 24, 2021Publication date: January 13, 2022Applicant: ORGANOVO, INC.Inventors: Keith MURPHY, Scott DORFMAN, Nathan SMITH, Larry BAUWENS, Ian SOHN, Tim MCDONALD, Chris LEIGH-LANCASTER, Richard Jin LAW
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Publication number: 20220009156Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: ApplicationFiled: September 22, 2021Publication date: January 13, 2022Applicant: ORGANOVO, INC.Inventors: Keith Murphy, Scott Dorfman, Nathan Smith, Larry Bauwens, Ian Sohn, Tim McDonald, Chris Leigh-Lancaster, Richard Jin Law
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Patent number: 11162939Abstract: Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. In this assay, the amount of the signal or the first member of the second binding pair bound to the binding agent is inversely proportional to the analyte in the sample.Type: GrantFiled: March 9, 2020Date of Patent: November 2, 2021Assignee: Enzo Life Sciences, Inc.Inventors: Jack Coleman, Maciej Szczepanik, Richard Jin
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Publication number: 20210325375Abstract: Provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule.Type: ApplicationFiled: June 17, 2021Publication date: October 21, 2021Applicant: Enzo Life Science, Inc.Inventors: Jack Coleman, Maciej Szczepanik, Richard Jin
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Publication number: 20210291432Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: ApplicationFiled: March 15, 2021Publication date: September 23, 2021Applicant: ORGANOVO, INC.Inventors: Keith Murphy, Scott Dorfman, Nathan Smith, Larry Bauwens, Ian Sohn, Tim McDonald, Chris Leigh-Lancaster, Richard Jin Law
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Patent number: 11073512Abstract: Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. Additionally provided is a multisignal labeling reagent comprising a first polymer covalently bound to (a) a reactive group or a first member of a first binding pair, and (b) more than one digoxigenin molecule.Type: GrantFiled: November 28, 2018Date of Patent: July 27, 2021Assignee: Enzo Life Sciences, Inc.Inventors: Jack Coleman, Maciej Szczepanik, Richard Jin
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Patent number: 11073438Abstract: A manifold assembly configured to measure differential pressure of fluid. The manifold assembly may have a monolithic body with an internally drilled fluid pathway. The body supports a differential pressure transducer that communicates, on either end, with the internally drilled fluid pathway. This configuration can generate data that defines pressure drop across impellers or other mechanisms on metrology hardware (or “gas meters”). Utilities can use this data to diagnose health or other conditions on the gas meter in the field.Type: GrantFiled: September 28, 2018Date of Patent: July 27, 2021Assignee: Natural Gas Solutions North America, LLCInventor: Richard Jin Yao
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Patent number: 10967560Abstract: Described herein are bioprinters comprising: one or more printer heads, wherein a printer head comprises a means for receiving and holding at least one cartridge, and wherein said cartridge comprises contents selected from one or more of: bio-ink and support material; a means for calibrating the position of at least one cartridge; and a means for dispensing the contents of at least one cartridge. Further described herein are methods for fabricating a tissue construct, comprising: a computer module receiving input of a visual representation of a desired tissue construct; a computer module generating a series of commands, wherein the commands are based on the visual representation and are readable by a bioprinter; a computer module providing the series of commands to a bioprinter; and the bioprinter depositing bio-ink and support material according to the commands to form a construct with a defined geometry.Type: GrantFiled: November 17, 2017Date of Patent: April 6, 2021Assignee: Organovo, Inc.Inventors: Keith Murphy, Scott Dorfman, Nathan Smith, Larry Bauwens, Ian Sohn, Tim McDonald, Chris Leigh-Lancaster, Richard Jin Law
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Publication number: 20200360392Abstract: The present invention relates to the field of therapeutic methods, compositions and uses thereof, that affect, directly or indirectly, the behavior of LRP receptors. These compositions and methods result in the treatment of inflammatory, immunological and metabolic conditions. More particularly, the methods and compositions of the invention are directed to the identification of small molecules, drugs and/or pharmacological agents that affect the Wnt pathway by affecting normal complex formation among various signaling receptors, the LRP5 and LRP6 receptor, and related ligands.Type: ApplicationFiled: April 21, 2020Publication date: November 19, 2020Applicant: ENZO BIOCHEM, INCInventors: Elazar Rabbani, Xiaofeng Li, Dakai Liu, Yazhou Zhang, Richard Jin, Riddhi Bhattacharyya, Wei Cheng, James J. Donegan
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Publication number: 20200284786Abstract: Provided is a composition comprising an analyte bound covalently or through a first binding pair to a polymer. In this composition, the analyte is less than about 2000 MW; the polymer further comprises more than one signal or first member of a second binding pair; and the analyte is not a member of the first binding pair or the second binding pair. Also provided is an assay for an analyte. The assay comprises: combining a sample suspected of containing the analyte with the above-described composition and a binding agent that binds to the analyte; and detecting the signal or the first member of the second binding pair that is bound to the binding agent. In this assay, the amount of the signal or the first member of the second binding pair bound to the binding agent is inversely proportional to the analyte in the sample.Type: ApplicationFiled: March 9, 2020Publication date: September 10, 2020Applicant: Enzo Life Science, Inc.Inventors: Jack Coleman, Maciej Szczepanik, Richard Jin
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Publication number: 20200200574Abstract: A sensor unit that is configured to improve the non-contact, magnetic interface on a gas meter. The configurations may include a pair of magnets that co-rotate in response to a magnet internal to the gas meter. At least one of the magnets may also move longitudinally in proximity to the internal magnet. This feature aligns the magnets with one another to ensure proper magnetic coupling with the internal magnet.Type: ApplicationFiled: December 18, 2019Publication date: June 25, 2020Inventors: Jeff Thomas Martin, Roman Leon Artiuch, Jeffrey Raynal, Richard Jin Yao
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Patent number: D1021299Type: GrantFiled: January 6, 2022Date of Patent: April 2, 2024Assignee: Techtronic Floor Care Technology LimitedInventors: Kevin Wolfe, Steve Davis, Yu-Jin Song, Francis McGovern, Richard David Waters