Patents by Inventor Richard John Bowen

Richard John Bowen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-tumor agents comprising pyridyl-substituted metal-diphosphine complex
    Patent number: 6218378
    Abstract: A method of treatment or inhibition of tumors including the steps of: (i) exchanging one or more of the eight phenyl substituents in the compound [M(dppe)2]+ where M is selected from Au(I), Ag(I) and Cu(I) by 2, 3, or 4 pyridyl substituents to provide a compound having anti-tumor activity and an octanol/water partition coefficient between 0.01 and 25.5; and (ii) administering said compound to a subject requiring treatment which compound has selective toxicity to cancer cells including cisplatin resistant human carcinoma cell lines.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: April 17, 2001
    Assignee: Griffith University
    Inventors: Susan Jane Berners-Price, Richard John Bowen, Peter Gordon Parsons
  • Method of treatment or inhibition of tumors using pyridyl-substituted metal-diphosphine complexes
    Patent number: 6159957
    Abstract: A method of treatment or inhibition of tumors involves administering a compound to a subject. The compound is one in which one or more of the eight phenyl substituents in the compound [M(dppe).sub.2 ].sup.+, in which M is selected from Au(I), Ag(I) and Cu(I), is substituted by 2, 3, or 4 pyridyl substituents. The compound has anti-tumor activity and an octanol/water partition coefficient between 0.01 and 25.5. The compound has selective toxicity to cancer cells, including cisplatin resistant human carcinoma cells lines.
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: December 12, 2000
    Assignee: Griffith University
    Inventors: Susan Jane Berners-Price, Richard John Bowen, Peter Gordon Parsons