Patents by Inventor Richard John Brennan

Richard John Brennan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH
    Publication number: 20120208776
    Abstract: A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided.
    Type: Application
    Filed: April 5, 2012
    Publication date: August 16, 2012
    Inventors: Linda Saxe Einbond, Morando Soffritti, Kyle Louis Kolaja, Richard John Brennan, I. Bernard Weinstein, Joan Weinstein, Tamara Weinstein, Claudia Weinstein, Matthew Weinstein
  • REAGENT SETS AND GENE SIGNATURES FOR NON-GENOTOXIC HEPATOCARCINOGENICITY
    Publication number: 20100021885
    Abstract: The invention discloses gene signatures for predicting onset of non-genotoxic hepatocarcinogenicity in a subject. The invention also provides methods, apparatuses and reagent sets useful for predicting non-genotoxic hepatocarcinogenicity based on expression levels of genes in specific gene signatures.
    Type: Application
    Filed: September 17, 2007
    Publication date: January 28, 2010
    Inventors: Mark Fielden, Richard John Brennan
  • Anti-neoplastic compositions comprising extracts of black cohosh
    Publication number: 20090264377
    Abstract: A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided.
    Type: Application
    Filed: October 21, 2008
    Publication date: October 22, 2009
    Inventors: Linda Saxe Einbond, Morando Soffritti, Kyle Louis Kolaja, Richard John Brennan, I. Bernard Weinstein, Joan Weinstein, Tamara Weinstein, Claudia Weinstein, Matthew Weinstein