Patents by Inventor Richard Joseph Fagan

Richard Joseph Fagan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treatment comprising administration of a cytokine antagonist molecule
    Patent number: 7803383
    Abstract: This invention relates to novel uses of a protein sequence (INSP052EC), herein identified as an immunoglobulin domain-containing cell surface recognition, in the diagnosis, prevention and treatment of diseases, in particular those related to the excessive expression and/or secretion of cytokines.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: September 28, 2010
    Assignee: Ares Trading S.A.
    Inventors: Richard Joseph Fagan, Andrew Robert Davids, Christopher Benjamin Phelps, Christine Power, Ursula Boschert, Yolande Chvatchko
  • Isolated INSP 163 protein
    Patent number: 7700724
    Abstract: This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: April 20, 2010
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke, Jadwiga Bienkowska
  • Cystine-Knot Fold Cytokine
    Publication number: 20100048467
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 12, 2006
    Publication date: February 25, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson, Yan Lavrovsky
  • Defensin Proteins
    Publication number: 20090324562
    Abstract: This invention relates to the novel proteins, termed INSP108 and INSP109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 31, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Cytokine antagonist molecules
    Patent number: 7622555
    Abstract: This invention relates to a novel protein (INSP052), herein identified as an immunoglobulin domain-containing cell surface recognition molecule and to the use of this proteins and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease. The invention also relates to the identification of the extracellular domain of INSP052.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: November 24, 2009
    Assignee: Ares Trading S.A.
    Inventors: Andrew Robert Davids, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Yolande Chvatchko, Ursula Boschert
  • Cystine-knot fold protein
    Patent number: 7619065
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: November 17, 2009
    Assignee: Ares Trading S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson
  • Splice variant of human placental growth hormone
    Patent number: 7605129
    Abstract: This invention relates to a protein, termed INSP105, herein identified as a splice variant of human placental growth hormone and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: October 20, 2009
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps, Tania Maria Rodrigues, Christine Power, Mariastella De Tiani
  • TGR3-Like Protein Receptor
    Publication number: 20090214548
    Abstract: There are provided proteins containing a domain corresponding to the C-terminal half of a ZP domain similar to that identified in TGF-beta Receptor III and the use of the proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of diseases. In particular, the present invention relates to the use of the disclosed proteins for modulating the activity of proteins belonging to the TGF-beta superfamily.
    Type: Application
    Filed: December 8, 2005
    Publication date: August 27, 2009
    Applicant: Ares Trading S.A.
    Inventors: David Michalovich, Richard James Mitter, Richard Joseph Fagan, Christine Power
  • Beta defensin proteins
    Patent number: 7563767
    Abstract: This invention relates to novel proteins, termed INSP 108 and INSP 109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: January 13, 2004
    Date of Patent: July 21, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Metalloprotease proteins
    Patent number: 7557079
    Abstract: This invention relates to proteins termed INSP005a and INSP005b, herein identified as secreted proteins, in particular members of the metalloprotease family and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: July 7, 2009
    Assignee: Ares Trading, S.A.
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Richard James Mitter, Ursula Boschert, Yolande Chvatchko
  • Splice variant of the human pituitary growth hormone
    Patent number: 7531508
    Abstract: This invention relates to a novel protein, termed INSP101, herein identified as a novel splice variant of human pituitary growth hormone and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: May 12, 2009
    Assignee: Ares Trading S.A.
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps, Tania Maria Rodrigues, Melanie Yorke, Mariastella De Tiani
  • TNF-like secreted protein
    Patent number: 7514533
    Abstract: This invention relates to novel protein INSP058, herein identified as TNF-like secreted protein, and to the use of this protein and the nucleic acid sequence from the encoding gene in the diagnosis, prevention, and treatment of disease.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: April 7, 2009
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Mark Ibberson, Melanie Yorke
  • Defensin Proteins
    Publication number: 20090042775
    Abstract: This invention relates to novel proteins, termed INSP 108 and INSP 109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 13, 2004
    Publication date: February 12, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Mam Domain Containing Protein
    Publication number: 20080213286
    Abstract: This invention relates to a novel protein, termed INSP152, herein identified as a secreted protein, in particular, as a MAM domain containing protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment.
    Type: Application
    Filed: October 18, 2005
    Publication date: September 4, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke
  • Lipocalin Protein
    Publication number: 20080196113
    Abstract: The invention is based on the discovery that the human protein referred to herein as INSP153 protein is a lipocalin.
    Type: Application
    Filed: October 14, 2005
    Publication date: August 14, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke
  • Cytokine Antagonist Molecules
    Publication number: 20080025951
    Abstract: This invention relates to novel uses of a protein sequence (INSP052EC), herein identified as an immunoglobulin domain-containing cell surface recognition, in the diagnosis, prevention and treatment of diseases, in particular those related to the excessive expression and/or secretion of cytokines.
    Type: Application
    Filed: November 12, 2004
    Publication date: January 31, 2008
    Applicant: ARES TRADING S.A.
    Inventors: Richard Joseph Fagan, Andrew Robert Davids, Christopher Benjamin Phelps, Christine Power, Ursula Boschert, Yolande Chvatchko
  • Nuclear hormone receptor ligand binding domain
    Publication number: 20040249132
    Abstract: This invention relates to a novel protein, termed LBDG3, herein identified as a Nuclear Hormone Receptor Ligand Binding Domain and to the use of this protein and nucleic acid sequence from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: June 14, 2004
    Publication date: December 9, 2004
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps, Valerie Nathalie Pierron, Kathryn Elizabeth Allen, Sarah Jane Neill
  • Nuclear hormone receptor ligand binding domain
    Publication number: 20040249123
    Abstract: This invention relates to a novel protein, termed BAA22563.1, herein identified as a Nuclear Hormone Receptor Ligand Binding Domain and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: April 9, 2004
    Publication date: December 9, 2004
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps, Tom Phillips, Valerie Nathalie Pierron, Kathryn Elizabeth Allen, Janet Marjorie Allen, Sarah Jane Neill
  • Cytokine antagonist molecules
    Publication number: 20040204352
    Abstract: This invention relates to a novel protein (INSP052), herein identified as an immunoglobulin domain-containing cell surface recognition molecule and to the use of this proteins and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease. The invention also relates to the identification of the extracellular domain of INSP052.
    Type: Application
    Filed: November 12, 2003
    Publication date: October 14, 2004
    Inventors: Andrew Robert Davids, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Yolande Chvatchko, Ursula Boschert
  • Nuclear hormone receptor ligand binding domain
    Publication number: 20040171804
    Abstract: This invention relates to a novel protein, termed BAA74848.1, herein identified as a Nuclear Hormone Receptor Ligand Binding Domain and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: March 25, 2004
    Publication date: September 2, 2004
    Inventors: Richard Joseph Fagan, Christopher Benjamin Phelps