Abstract: A cooler, a cooler platform assembly, and a process of adjusting a cooler platform are disclosed. The cooler includes a cooling region, a discharge region, and a cooler platform positioned in the discharge region and proximal to a sloped interior section of the cooler. The cooler platform assembly includes a cooler platform, a sloped interior section of a cooler proximal to a first end of the cooler platform, and a vertical wall proximal to a second end of the cooler platform. The process includes adjusting a cooler platform from a retracted position substantially parallel to a vertical wall of a cooler to a deployed position substantially perpendicular to the vertical wall.

Abstract: In some cases, it may be desirable to limit the number of routers in a mesh network. Various techniques to limit the number of routers, without affecting connectivity, are disclosed. In some embodiments, a node enables its router capability if there are less than a predetermined number of routers already in the network. In other embodiments, a node enables its routing capability only is it is necessary to resolve a connectivity issue or a biconnectivity issue. In some cases, a node, which previously enabled its router capability, may no longer be required to be a router. In some embodiments, this node, upon making this determination, disables its routing capability.

Abstract: Methods of reassembling a mesh network which has been disrupted by the unavailability of a node or a link are disclosed. Nodes continuously receive beacon messages originating from a leader node. These beacon messages may be transmitted directly by the leader node, or may have been retransmitted by an intermediate node. When a node determines that it has not received a beacon message in a certain time period, it concludes that it is now disconnected from that leader node. At this point, it may choose to act as a leader node and form a new network, or may join with another network. The determination of which network to join may be based on some indicia associated with the leader node of that network.

Abstract: A method of efficiently disseminating various types of information throughout a mesh network is disclosed. Information is typically propagated through the network using a variety of protocols and messages. However, in one embodiment, a single message, communicates all of this information at once. The message includes data originating at the leader, which does not change as the messages are propagated through the network, as well as topology and link information that is created by the forwarding nodes. The data originating at the leader includes the identity of the leader node and a sequence number. Additionally, a version number is included by the leader which represents the state of the quasi-static information. Quasi-static information may include, for example, the identity of a node that has access to a central control system or the internet. This compact message format allows improved efficiency and use of the network.

Abstract: In some cases, it may be desirable to limit the number of routers in a mesh network. Various techniques to limit the number of routers, without affecting connectivity, are disclosed. In some embodiments, a node enables its router capability if there are less than a predetermined number of routers already in the network. In other embodiments, a node enables its routing capability only is it is necessary to resolve a connectivity issue or a biconnectivity issue. In some cases, a node, which previously enabled its router capability, may no longer be required to be a router. In some embodiments, this node, upon making this determination, disables its routing capability.

Abstract: In some cases, it may be desirable to limit the number of routers in a mesh network. Various techniques to limit the number of routers, without affecting connectivity, are disclosed. In some embodiments, a node enables its router capability if there are less than a predetermined number of routers already in the network. In other embodiments, a node enables its routing capability only is it is necessary to resolve a connectivity issue or a biconnectivity issue. In some cases, a node, which previously enabled its router capability, may no longer be required to be a router. In some embodiments, this node, upon making this determination, disables its routing capability.

Abstract: Methods of reassembling a mesh network which has been disrupted by the unavailability of a node or a link are disclosed. Nodes continuously receive beacon messages originating from a leader node. These beacon messages may be transmitted directly by the leader node, or may have been retransmitted by an intermediate node. When a node determines that it has not received a beacon message in a certain time period, it concludes that it is now disconnected from that leader node. At this point, it may choose to act as a leader node and form a new network, or may join with another network. The determination of which network to join may be based on some indicia associated with the leader node of that network.

Abstract: In some cases, it may be desirable to limit the number of routers in a mesh network. Various techniques to limit the number of routers, without affecting connectivity, are disclosed. In some embodiments, a node enables its router capability if there are less than a predetermined number of routers already in the network. In other embodiments, a node enables its routing capability only is it is necessary to resolve a connectivity issue or a biconnectivity issue. In some cases, a node, which previously enabled its router capability, may no longer be required to be a router. In some embodiments, this node, upon making this determination, disables its routing capability.

Abstract: A method of efficiently disseminating various types of information throughout a mesh network is disclosed. Information is typically propagated through the network using a variety of protocols and messages. However, in one embodiment, a single message, communicates all of this information at once. The message includes data originating at the leader, which does not change as the messages are propagated through the network, as well as topology and link information that is created by the forwarding nodes. The data originating at the leader includes the identity of the leader node and a sequence number. Additionally, a version number is included by the leader which represents the state of the quasi-static information. Quasi-static information may include, for example, the identity of a node that has access to a central control system or the internet. This compact message format allows improved efficiency and use of the network.

Abstract: A pharmaceutical composition which comprises a pharmaceutically acceptable carrier or diluent and: (a) an inhibitor of the RSV fusion protein; and (b) a benzodiazepine derivative capable of inhibiting RSV replication is found to be highly active against RSV.

Abstract: A cooling system, a motor handling system, and a method of positioning a motor in a cooling system are disclosed. The motor handling system includes a suspension feature configured to engage a support member, the support member positioned partially below a cooler. The motor handling system permits positioning of a motor in a first position and re-positioning of the motor to a second position. The cooling system includes a cooler, a support member positioned partially below the cooler, and a motor handling system. The method of positioning includes engaging a support member of a cooling system with a suspension feature, positioning the motor at a first position, and re-positioning the motor at a second position.

Abstract: Benzodiazepine derivative of formula (I), and pharmaceutically acceptable salts thereof, are found to be active against RSV Formula (I) Wherein: —R1 represents C1-6 alkyl, aryl or heteroaryl; —R2 represents hydrogen or C1-6 alkyl; -each R3 is the same or different and represents halogen, hydroxy, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio C1-6 haloalkyl, C1-6 haloalkoxy, amino, mono(C1-6 alkyl)amino, di(C1-6 alkyl)amino, nitro, cyano, —CO2R?, CONR?R?, —NH—CO—R?, —S(O)R?, —S(O)2R?, —NH—S(O)2R?, —S(O)NR?R? or —S(O)2NR?R? wherein each R? and R? is the same or different and represents hydrogen or C1-6 alkyl; -n is from 0 to 3; R4 represents hydrogen or C1-6 alkyl; —R6 represents C1-6 alkyl, aryl, heteroaryl, carbocyclyl, heterocyclyl, aryl-(C1-6 alkyl)-, heteroaryl-(C1-6 alkyl)-, carbocyclyl-(C1-6 alkyl)-, heterocyclyl-(C1-6 alkyl)-, aryl-C(O)—C(O)—, heteroaryl-C(O)—C(O)—, carbocyclyl-C(O)—C(O)—, heterocyclyl-C(O)—C(O)— or, —XR6; —X represents —CO—, —S(O)— or —S(0)2—; and —R6 represents C1-6 alkyl, hydroxy, C1-6 alk

Abstract: Benzodiazepine derivative of formula (I), and pharmaceutically acceptable salts thereof, are found to be active against RSV Formula (I) Wherein: —R1 represents C1-6 alkyl, aryl or heteroaryl; —R2 represents hydrogen or C1-6 alkyl; -each R3 is the same or different and represents halogen, hydroxy, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio C1-6 haloalkyl, C1-6 haloalkoxy, amino, mono(C1-6 alkyl)amino, di(C1-6 alkyl)amino, nitro, cyano, —CO2R?, CONR?R?, —NH—CO—R?, —S(O)R?, —S(O)2R?, —NH—S(O)2R?, —S(O)NR?R? or —S(O)2NR?R? wherein each R? and R? is the same or different and represents hydrogen or C1-6 alkyl; -n is from 0 to 3; R4 represents hydrogen or C1-6 alkyl; —R6 represents C1-6 alkyl, aryl, heteroaryl, carbocyclyl, heterocyclyl, aryl-(C1-6 alkyl)-, heteroaryl-(C1-6 alkyl)-, carbocyclyl-(C1-6 alkyl)-, heterocyclyl-(C1-6 alkyl)-, aryl-C(O)—C(O)—, heteroaryl-C(O)—C(O)—, carbocyclyl-C(O)—C(O)—, heterocyclyl-C(O)—C(O)— or, —XR6; —X represents —CO—, —S(O)— or —S(0)2—; and —R6 represents C1-6 alkyl, hydroxy, C1-6 alk

Abstract: Use of a compound which is (a) a benzodiazepine derivative of the formula (I) or an N-oxide thereof or (b) a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in treating or preventing an RSV infection wherein: —R1 represents C1-6 alkyl, aryl or heteroaryl; —R2 represents hydrogen or C1-6 alkyl; each R3 is the same or different and represents halogen, hydroxy, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, C1-6 haloalkyl, C1-6 haloalkoxy, amino, mono(C1-6 alkyl)amino, di(C1-6alkyl)amino, vitro, cyano, —CO2R?, —CONR?R?, —NH—CO—R?, —S(O)R?, —S(O)2R?, —NH—S(O)2R?, —S(O)NR?R? or —S(O)2NR?R?, wherein each R? and R? is the same or different and represents hydrogen or C1-6 alkyl; n is from O to 3; R4 represents hydrogen or C1-6 alkyl; X represents —CO—, —CO—NR?—, —S(O)— or —S(O)2—, wherein R? is hydrogen or a C1-C6 alkyl group; and R5 represents a heteroaryl or heterocyclyl group which is substituted by a C1C6 hydroxyalkyl group or a —(C1-C4 alkyl)-X1—(C1-C4 alkyl)-X2—(C1-C4 alkyl} group

Abstract: A process for producing a compound which is a benzodiazepine derivative of formula: (I) wherein: represents or R1 represents C1-6 alkyl, aryl or heteroaryl; each R3 is the same or different and represents halogen, hydroxy, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, C1-6 haloalkyl, C1-6 haloalkoxy, amino, mono(C1-6 alkyl)amino, di(C1-6 alkyl)amino, nitro, cyano, —CO2R?, —CONR?R?, —NH—CO—R?, —S(O)R?, —S(O)2R?, —NH—S(O)2R?, —S(O)NR?R? or —S(O)2NR?R?, wherein each R? and R? is the same or different and represents hydrogen or C1-6 alkyl; n is from 0 to 3; X represents —NH—, —N(C1-C6alkyl)-, —CO—, —CO—NR?—, —S(O)— or —S(O)2—, wherein R? is hydrogen or a C1-C6 alkyl group; and R4 represents hydrogen; or —CO—R4? or —CO—NH—R4 ?, wherein R4 ? is a C1-C6 alkyl, C1-C6 hydroxyalkyl, aryl, heteroaryl, carbocyclyl or heterocyclyl group, which group is substituted by a C1-C6 hydroxyalkyl, aryl, heteroaryl, carbocyclyl or heterocyclyl group or a —(C1-C4 alkyl)-X1—(C1-C4 alkyl)-X2—(C1-C4 alkyl) group, wherein X1 represents —

Abstract: A pharmaceutical composition which comprises a pharmaceutically acceptable carrier or diluent and: (a) an inhibitor of the RSV fusion protein; and (b) a benzodiazepine derivative capable of inhibiting RSV replication is found to be highly active against RSV.

Abstract: A pharmaceutical composition which comprises a pharmaceutically acceptable carrier or diluent and: (a) an inhibitor of the RSV fusion protein; and (b) a benzodiazepine derivative capable of inhibiting RSV replication is found to be highly active against RSV.

Abstract: Benzodiazepine derivative of formula (I), and pharmaceutically acceptable salts thereof, are found to be active against RSV.

Abstract: In a method for directing packets in a radio network, a route of nodes from an origin to a destination is determined according to a routing algorithm. A packet is transmitted along the route. A failure of a first node to forward the packet along the route is detected. The packet is transmitted to the destination from a second node not on the route.

Abstract: A wireless mesh network includes nodes of a first type and nodes of a second type. Packets are routed from nodes of the first type to nodes of the second type using a first routing protocol, and packet are routed from nodes of the second type to nodes of the first type using a second routing protocol that differs from the first routing protocol.