Abstract: The inventors discovered that the ErbB2 signal transduction pathway can activate ERR? by inducing its phosphorylation. Based on this discovery, the present invention provides methods for determining whether a breast cancer patient is likely to respond to hormonal-blockade therapy or ErbB2-based therapy, methods for determining prognosis of breast cancer patients, methods for treating breast cancer, and methods for identifying agents that can modulate ERR? phosphorylation.

Abstract: In a computerized automotive vehicle diagnostic system, a test probe cable is attached to individual components and consists of a multiple conductor cable which is attached ultimately to the component and to a computer in a technician terminal. Where the probe cable enters the technician terminal the conductors contained within it are fed into a programmable crosspoint switch which is controlled by a microcontroller. Test functions are provided by three programmable resources: (1) A program controlled multimeter, (2) A program controlled DC voltage source and ground sink; and (3) the microcontroller itself which receives and interprets commands from the computer and controls the various probe elements based upon the test commands received.

Abstract: A device for detecting the presence of water includes a capacitance sensor coupled to a windshield to detect capacitance changes. A multivibrator is coupled to the sensor to translate the detected capacitance change to the frequency domain. A phase-locked loop coupled to the multivibrator produces a phase pulse in response to water causing a change in capacitance and, in turn, a change in the frequency of the multivibrator.

Abstract: A DC voltage up-converter circuit having an inductor in series between the relatively low value of DC voltage and the stepped up output of the circuit, wherein the output end of the inductor is periodically switched to ground potential and an output storage capacitor stores the energy surges which result when the ground connection is disconnected. The cathode of a zener diode is connected to the output to provide a limit to the output of the circuit and the anode of the zener diode is connected to means for control limiting the amount of current through the switching means when said ground potential is connected.

Abstract: An electronic current sensor and controller for automatically controlling the extension and retraction of a power antenna with the energization and de-energization of an automobile radio receiver.