Patents by Inventor Richard L. Beissinger

Richard L. Beissinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxygen carrying multiple emulsions
    Patent number: 5438041
    Abstract: A process is provided wherein hemoglobin, a fragile material, is formulated into high hemoglobin content water-in-oil-in-water multiple emulsion while maintaining high yields and high oxygen exchange activity. A multiple emulsion of aqueous oxygen carrying material in oil in outer aqueous phase is suitable for provision of oxygen for oxygen transfer processes. A hemoglobin multiple emulsion in physiologically compatible oil in an outer aqueous saline solution is provided in sufficiently small droplet size to provide oxygen flow through blood vessels to desired body tissues or organs thereby providing a blood substitute.
    Type: Grant
    Filed: March 3, 1993
    Date of Patent: August 1, 1995
    Assignees: Illinois Institute of Technology, Northfield Laboratories, Inc.
    Inventors: Shuming Zheng, Richard L. Beissinger, Darsh T. Wasan, Lakshman R. Sehgal, Arthur L. Rosen
  • Process for preparation of hemoglobin multiple emulsions
    Patent number: 5217648
    Abstract: A process is provided wherein hemoglobin, a fragile material, is formulated into high hemoglobin content water-in-oil-in-water multiple emulsion while maintaining high yields and high oxygen exchange activity. A multiple emulsion of aqueous oxygen carrying material in oil in outer aqueous phase is suitable for provision of oxygen for oxygen transfer processes. A hemoglobin multiple emulsion in physiologically compatible oil in an outer aqueous saline solution is provided in sufficiently small droplet size to provide oxygen flow through blood vessels to desired body tissues or organs thereby providing a blood substitute.
    Type: Grant
    Filed: October 11, 1991
    Date of Patent: June 8, 1993
    Assignees: Illinois Institute of Technology, Northfield Laboratories, Inc.
    Inventors: Richard L. Beissinger, Darsh T. Wasan, Lakshman R. Sehgal, Arthur L. Rosen
  • Hemoglobin multiple emulsion
    Patent number: 5061688
    Abstract: A multiple emulsion of aqueous oxygen carrying material in oil in outer aqueous phase is suitable for provision of oxygen for oxygen transfer processes. A hemoglobin multiple emulsion in physiologically compatible oil in an outer aqueous saline solution is provided in sufficiently small droplet size to provide oxygen flow through blood vessels to desired body tissues or organs thereby providing a blood substitute. A process is provided wherein hemoglobin, a fragile material, is formulated into high hemoglobin content water-in-oil-in-water multiple emulsions while maintaining high yields and high oxygen exchange activity.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: October 29, 1991
    Assignees: Illinois Institute of Technology, Northfield Laboratories, Inc.
    Inventors: Richard L. Beissinger, Darsh T. Wasan, Lahksman R. Sehgal, Arthur L. Rosen
  • Blood substitute comprising liposome-encapsulated hemoglobin
    Patent number: 4911929
    Abstract: Sterile liposome-encapsulated hemoglobin having an oxygen carrying capacity of 20 vol/%, a half life of 15-20 hours as measured in mice, with the liposome made from chloroform, HSPC, cholesterol, negatively charged DMPG and alpha-tocopherol.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: March 27, 1990
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Martha C. Farmer, Richard L. Beissinger
  • Scaled-up production of liposome-encapsulated hemoglobin
    Patent number: 4776991
    Abstract: A method for making sterile liposome-encapsulated hemoglobin having an oxn carrying capacity of 20 vol/%, a half life of 15-20 hours as measured in mice, with the liposome made from chloroform, HSPC, cholesterol, negatively charged DMPG and alpha-tocopherol.
    Type: Grant
    Filed: August 29, 1986
    Date of Patent: October 11, 1988
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Martha C. Farmer, Richard L. Beissinger