Patents by Inventor Richard L. Keenan
Richard L. Keenan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9421311Abstract: A catheter pump is disclosed herein. The catheter pump can include a catheter assembly that comprises a drive shaft and an impeller coupled to a distal end of the drive shaft. A driven assembly can be coupled to a proximal end of the drive shaft within a driven assembly housing. The catheter pump can also include a drive system that comprises a motor and a drive magnet coupled to an output shaft of the motor. The drive system can include a drive assembly housing having at least one magnet therein. Further, a securement device can be configured to prevent disengagement of the driven assembly housing from the drive assembly housing during operation of the pump.Type: GrantFiled: March 13, 2013Date of Patent: August 23, 2016Assignee: THORATEC CORPORATIONInventors: Adam R. Tanner, Richard L. Keenan, Doug M. Messner, Michael R. Butler
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Patent number: 9387315Abstract: A retainer (34) is provided for holding a microprotrusion member (44) for application of the microprotrusion member (44) to the stratum corneum with an impact applicator (10). The microprotrusion member (44) includes a plurality of microprotrusions (90) which penetrate the stratum corneum to improve transport of an agent across the stratum corneum.Type: GrantFiled: June 17, 2014Date of Patent: July 12, 2016Assignee: Alza CorporationInventors: Joseph C. Trautman, Richard L. Keenan
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Patent number: 9381288Abstract: Various embodiments of a fluid handling system are disclosed herein. For example, the fluid handling system can include a catheter assembly and a console configured to control the operation of the catheter assembly. A removable interface member can be configured to provide fluid and electrical communication between the catheter assembly and the console.Type: GrantFiled: March 11, 2014Date of Patent: July 5, 2016Assignee: THORATEC CORPORATIONInventors: Alan Schenck, Michael L. Green, Keif M. Fitzgerald, Paul F. Muller, Joseph P. Sullivan, Keith Schubert, Peter W. Bristol, Jeffrey Paul Mills, Paul C. Leonard, Richard L. Keenan
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Patent number: 9358329Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: GrantFiled: March 13, 2013Date of Patent: June 7, 2016Assignee: THORATEC CORPORATIONInventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Publication number: 20160074644Abstract: An applicator device (10) is provided for applying a patch (44) having an array of microprotrusions (90) to the stratum corneum. The applicator device (10) includes a device body (12) and a piston moveable within the device body (12). A cap (16) is provided on the device body (12) for activating the device (10) to impact the stratum corneum with a microprotrusion array (44,90). The device (10) is capable of being cocked by one handed operation of the user which allows the device (10) to be used by patients having neither the strength nor the manual dexterity to cock other types of applicator devices.Type: ApplicationFiled: November 23, 2015Publication date: March 17, 2016Inventors: MICHAEL T. CAO, RICHARD L. KEENAN, JOSEPH C. TRAUTMAN
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Publication number: 20150290372Abstract: Sensors for catheter pumps are disclosed herein. The catheter pump can include a catheter assembly comprising a catheter and a cannula coupled to a distal portion of the catheter. The cannula can have a proximal port for permitting the flow of blood therethrough. The catheter assembly can include a sensor to be disposed near the proximal port. A processing unit can be programmed to process a signal detected by the sensor. The processing unit can comprise a computer-readable set of rules to evaluate the signal to determine a position of the cannula relative to an aortic valve of a patient.Type: ApplicationFiled: April 15, 2015Publication date: October 15, 2015Inventors: Paul F. Muller, Keif M. Fitzgerald, Richard L. Keenan, Veronica J. Neiman
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Publication number: 20150290371Abstract: A catheter pump is disclosed herein. The catheter pump can include an elongate catheter body and an impeller assembly coupled to a distal portion of the elongate catheter body. The impeller assembly can comprise an impeller configured to rotate during operation of the catheter pump. A tube can extend through at least portions of the elongate catheter body and the impeller assembly. The tube can extend distal the impeller and can be configured to remain in the portions of the elongate catheter body and the impeller assembly during operation of the catheter pump.Type: ApplicationFiled: April 15, 2015Publication date: October 15, 2015Inventors: Paul F. Muller, Keif M. Fitzgerald, Richard L. Keenan
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Patent number: 9067007Abstract: A catheter pump is disclosed herein. The catheter pump can include a catheter assembly that comprises a drive shaft and an impeller coupled to a distal end of the drive shaft. A driven assembly can be coupled to a proximal end of the drive shaft within a driven assembly housing. The catheter pump can also include a drive system that comprises a motor and a drive magnet coupled to an output shaft of the motor. The drive system can include a drive assembly housing having at least one magnet therein. Further, a securement device can be configured to prevent disengagement of the driven assembly housing from the drive assembly housing during operation of the pump.Type: GrantFiled: March 13, 2013Date of Patent: June 30, 2015Assignee: THORATEC CORPORATIONInventors: Adam R. Tanner, Richard L. Keenan, Doug M. Messner, Michael R. Butler
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Publication number: 20140364801Abstract: A retainer (34) is provided for holding a microprotrusion member (44) for application of the microprotrusion member (44) to the stratum corneum with an impact applicator (10). The microprotrusion member (44) includes a plurality of microprotrusions (90) which penetrate the stratum corneum to improve transport of an agent across the stratum corneum.Type: ApplicationFiled: June 17, 2014Publication date: December 11, 2014Inventors: Joseph C. Trautman, Richard L. Keenan
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Publication number: 20140275725Abstract: Various embodiments of a fluid handling system are disclosed herein. For example, the fluid handling system can include a catheter assembly and a console configured to control the operation of the catheter assembly. A removable interface member can be configured to provide fluid and electrical communication between the catheter assembly and the console.Type: ApplicationFiled: March 11, 2014Publication date: September 18, 2014Applicant: THORATEC CORPORATIONInventors: Alan Schenck, Michael L. Green, Keif M. Fitzgerald, Paul F. Muller, Joseph P. Sullivan, Keith Schubert, Peter W. Bristol, Jeffrey Paul Mills, Paul C. Leonard, Richard L. Keenan
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Patent number: 8753318Abstract: A retainer (34) is provided for holding a microprotrusion member (44) for application of the microprotrusion member (44) to the stratum corneum with an impact applicator (10). The microprotrusion member (44) includes a plurality of microprotrusions (90) which penetrate the stratum corneum to improve transport of an agent across the stratum corneum.Type: GrantFiled: November 1, 2004Date of Patent: June 17, 2014Assignee: Alza CorporationInventors: Joseph C. Trautman, Richard L. Keenan
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Publication number: 20140012065Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.Type: ApplicationFiled: March 13, 2013Publication date: January 9, 2014Inventors: Keif M. Fitzgerald, Richard L. Keenan, William J. Harrison
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Patent number: 8597170Abstract: A heart pump and a catheter assembly therefor are provided that include a flexible catheter body having a proximal end and a distal end, the catheter body having a plurality of lumens therethrough. The catheter body can be sufficiently flexible to extend from a peripheral access to a patient's heart. The catheter assembly can also include an impeller assembly having an impeller and a housing. The impeller assembly can be coupled with the flexible catheter body such that a tensile force applied to opposite ends of the catheter assembly enhances the security of the connection between the catheter body and the impeller assembly.Type: GrantFiled: January 4, 2012Date of Patent: December 3, 2013Assignees: Thoratec Corporation, The Penn State Research FoundationInventors: Daniel A. Walters, William James Repka, Kevin J. Powell, Richard L. Keenan, Justin M. Walsh, Robert L. Campbell, Mark W. McBride
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Publication number: 20130303970Abstract: In various embodiments, a catheter pump is disclosed herein. The catheter pump can include an elongated catheter body having a distal portion including an expandable cannula having an inlet and an outlet. The expandable cannula can have a delivery profile and an operational profile larger than the delivery profile. An impeller assembly can include an impeller shaft, and an impeller body can include one or more blades. The impeller blades can draw blood into the cannula when rotated. Further, an expandable support can have a mounting portion disposed on the impeller shaft distal of the impeller body and a cannula contact portion for reducing a change in tip gap due to bending of the cannula. The cannula contact portion can be disposed distal of the mounting portion.Type: ApplicationFiled: March 13, 2013Publication date: November 14, 2013Inventors: Richard L. Keenan, Keif M. Fitzgerald
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Publication number: 20120172656Abstract: A heart pump and a catheter assembly therefor are provided that include a flexible catheter body having a proximal end and a distal end, the catheter body having a plurality of lumens therethrough. The catheter body can be sufficiently flexible to extend from a peripheral access to a patient's heart. The catheter assembly can also include an impeller assembly having an impeller and a housing. The impeller assembly can be coupled with the flexible catheter body such that a tensile force applied to opposite ends of the catheter assembly enhances the security of the connection between the catheter body and the impeller assembly.Type: ApplicationFiled: January 4, 2012Publication date: July 5, 2012Inventors: Daniel A. Walters, William James Repka, Kevin J. Powell, Richard L. Keenan, Justin M. Walsh, Robert L. Campbell, Mark W. McBride
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Patent number: 7798987Abstract: A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.Type: GrantFiled: March 28, 2005Date of Patent: September 21, 2010Assignee: Alza CorporationInventors: Joseph C. Trautman, Richard L. Keenan, Ahmad P. Samiee, WeiQi Lin, Michel J. N. Cormier, James A. Matriano, Peter E. Daddona
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Patent number: 7419481Abstract: A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.Type: GrantFiled: March 28, 2005Date of Patent: September 2, 2008Assignee: ALZA CorporationInventors: Joseph C. Trautman, Richard L. Keenan, Ahmad P. Samiee, WeiQi Lin, Michel J. N. Cormier, James A. Matriano, Peter E. Daddona
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Patent number: 7131960Abstract: A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.Type: GrantFiled: October 12, 2001Date of Patent: November 7, 2006Assignee: Alza CorporationInventors: Joseph C. Trautman, Richard L. Keenan, Ahmad P. Samiee, WeiQi Lin, Michel J. N. Cormier, James A. Matriano, Peter E. Daddona
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Patent number: 6855131Abstract: A retainer (34) is provided for holding a microprotrusion member (44) for application of the microprotrusion member (44) to the stratum corneum with an impact applicator (10). The microprotrusion member (44) includes a plurality of microprotrusions (90) which penetrate the stratum corneum to improve transport of an agent across the stratum corneum.Type: GrantFiled: October 12, 2001Date of Patent: February 15, 2005Assignee: Alza CorporationInventors: Joseph C. Trautman, Richard L. Keenan
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Publication number: 20020193729Abstract: Skin patches (20) having a microprojection array (10), a reservoir (18) containing an antigenic agent and an immune response augmenting adjuvant, and methods of using same to vaccinate animals (e.g., humans) is disclosed. In a preferred embodiment, the microprojection arrays (10) are composed of a photoetched and micro-punched titanium foil (14). The microprojections (12) are coated with a liquid formulation containing a vaccine antigen and an adjuvant such as glucosaminyl muramyl dipeptide, dried, and applied to skin of the animal to be vaccinated using an impact applicator. The microprojections (12) create superficial pathways through the stratum corneum to facilitate permeation of antigenic agent and adjuvant. Antigen dose and depth of penetration can be controlled. This technology has broad applicability for a wide variety of therapeutic vaccines to improve efficacy, and convenience of use.Type: ApplicationFiled: April 20, 2002Publication date: December 19, 2002Inventors: Michel J.N. Cormier, James A. Matriano, Peter E. Daddona, Juanita A. Johnson, Wendy A. Young, Richard L. Keenan, Joseph C. Trautman