Patents by Inventor Richard L. Monaghan

Richard L. Monaghan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Discovery of antibiotic L-681,217 in fermentation broth
    Patent number: 4476139
    Abstract: The antibiotic, L-681,217, having antibacterial and growth-permittant activity, is produced by fermentation of Streptomyces cattleya in a suitable nutrient media.
    Type: Grant
    Filed: September 29, 1982
    Date of Patent: October 9, 1984
    Assignee: Merck & Co., Inc.
    Inventors: August J. Kempf, Kenneth E. Wilson, Otto D. Hensens, Richard L. Monaghan, Sheldon B. Zimmerman, Eugene L. Dulaney
  • Hypocholesterolemic fermentation products and process of preparation
    Patent number: 4432996
    Abstract: Substances isolated after cultivation of a micoorganism belonging to the genus Penicillium in a culture medium comprises compounds which have strucures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesterolemic and hypolipemic medicaments.
    Type: Grant
    Filed: May 17, 1982
    Date of Patent: February 21, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Vincent P. Gullo, Tony Y. K. Lam, Richard L. Monaghan
  • Antiparasitic macrolide from a strain of Streptomyces hygroscopicus
    Patent number: 4390546
    Abstract: There is disclosed a macrolide isolated from the fermentation broth of a microorganism identified as MA-5285 which morphological analysis reveals to be a strain of Streptomyces hygroscopicus. The compound's structure is presented based upon analytical studies. The compound has insecticidal and antiparasitic activity.
    Type: Grant
    Filed: December 7, 1981
    Date of Patent: June 28, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Michael A. Goetz, Pamela A. McCormick, Richard L. Monaghan
  • Hypocholesterolemic fermentation products
    Patent number: 4343814
    Abstract: Substances isolated after cultivation of a microorganism belonging to the genus Penicillium in a culture medium comprises compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesterolemic and hypolipemic medicaments.
    Type: Grant
    Filed: November 17, 1980
    Date of Patent: August 10, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Vincent P. Gullo, Tony Y. K. Lam, Richard L. Monaghan
  • Hypocholesteremic fermentation products
    Patent number: 4342767
    Abstract: Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
    Type: Grant
    Filed: June 16, 1980
    Date of Patent: August 3, 1982
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Richard L. Monaghan, Alfred W. Alberts, Carl H. Hoffman
  • Process for producing Tunicamycin
    Patent number: 4330624
    Abstract: The antibiotic Tunicamycin is produced by fermenting a Tunicamycin-producing strain of Streptomyces (Streptomyces griseus ATCC 31591) under controlled conditions in a suitable nutrient medium and isolating the antibiotic so produced from the fermentation medium.
    Type: Grant
    Filed: December 3, 1980
    Date of Patent: May 18, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Enrique Tejera, Sara A. Currie, James E. Flor, Richard L. Monaghan
  • Hypocholesteremic fermentation products and process of preparation
    Patent number: 4294926
    Abstract: Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise a compound designated MSD803 which has the lactone structure: ##STR1## as well as its free hydroxy acid form. Together with salts and esters of the free acid form, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
    Type: Grant
    Filed: January 23, 1980
    Date of Patent: October 13, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Richard L. Monaghan, Alfred W. Alberts, Carl H. Hoffman, George Albers-Schonberg
  • Hypocholesteremic fermentation products and process of preparation
    Patent number: 4231938
    Abstract: Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise a compound designated MSD803 which has the lactone structure: ##STR1## as well as its free hydroxy acid form. Together with salts and esters of the free acid form, these compounds form a class of highly active hypocholesteremic and hypolipemic medicaments.
    Type: Grant
    Filed: June 15, 1979
    Date of Patent: November 4, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Richard L. Monaghan, Alfred W. Alberts, Carl H. Hoffman, George Albers-Schonberg