Patents by Inventor Richard L. Reim

Richard L. Reim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • E. coli secretory strains
    Patent number: 5578464
    Abstract: Strains of E. coli are provided which are capable of secreting heterologous recombinant proteins through the outer cell wall and directly into the culture medium. Methods are also provided for making and identifying such strains, and for using them to make heterologous proteins that have high biological activity, without the need for cell disruption.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: November 26, 1996
    Assignee: Schering Corporation
    Inventors: Charles A. Lunn, Satwant K. Narula, Richard L. Reim
  • Expression systems utilizing bacteriophage T7 promoters, gene sequences, and T7 RNA polymerase
    Patent number: 5122457
    Abstract: Expression systems which utilize bacteriophage T7 RNA mutant polymerases and promoter regions are provided by this invention. These systems are utilized to produce large quantities of useful polypeptides and proteins.
    Type: Grant
    Filed: October 19, 1989
    Date of Patent: June 16, 1992
    Assignee: Schering Corporation
    Inventors: Richard L. Reim, Satwant K. Narula, Michael J. Ryan, Paul J. Leibowitz