Patents by Inventor Richard L. Remmele

Richard L. Remmele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING A P75 TUMOR NECROSIS FACTOR RECEPTOR/IG FUSION PROTEIN
    Publication number: 20220025016
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: August 3, 2021
    Publication date: January 27, 2022
    Inventors: Wayne Richard Gombotz, Richard L. Remmele, JR.
  • Compositions comprising a P75 tumor necrosis factor receptor/Ig fusion protein
    Patent number: 11104714
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: August 31, 2021
    Assignee: IMMUNEX CORPORATION
    Inventors: Wayne Richard Gombotz, Richard L. Remmele, Jr.
  • COMPOSITIONS COMPRISING A P75 TUMOR NECROSIS FACTOR RECEPTOR/IG FUSION PROTEIN
    Publication number: 20190292237
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: April 26, 2019
    Publication date: September 26, 2019
    Inventors: Wayne Richard Gombotz, Richard L. Remmele, JR.
  • Lyophilized therapeutic peptibody formulations
    Patent number: 10166189
    Abstract: The present invention provides long-term stable formulations of a lyophilized therapeutic peptibody and methods for making a lyophilized composition comprising a therapeutic peptibody.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: January 1, 2019
    Assignee: AMGEN INC.
    Inventors: William J. Callahan, Richard L. Remmele, Jr., Gayathri Ratnaswamy, Ramil F. Latypov, Dingjiang Liu
  • Antibody formulations
    Patent number: 9920114
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: March 20, 2018
    Assignee: AMGEN INC.
    Inventors: Bruce D. Mason, Jifeng Zhang, Richard L. Remmele, Jr.
  • ANTIBODY FORMULATIONS
    Publication number: 20170210792
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: March 16, 2017
    Publication date: July 27, 2017
    Applicant: AMGEN INC.
    Inventors: Bruce D. Mason, Jifeng Zhang, Richard L. Remmele, JR.
  • COMPOSITIONS COMPRISING A P75 TUMOR NECROSIS FACTOR RECEPTOR/IG FUSION PROTEIN
    Publication number: 20170051039
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: November 2, 2016
    Publication date: February 23, 2017
    Applicant: Immunex Corporation
    Inventors: Wayne Richard Gombotz, Richard L. Remmele, JR.
  • Compositions comprising a p75 tumor necrosis factor receptor/Ig fusion protein
    Patent number: 9518111
    Abstract: The present invention relates to pharmaceutical compositions comprising a p75 tumor necrosis factor receptor/Ig fusion protein.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: December 13, 2016
    Assignee: Immunex Corporation
    Inventors: Wayne Richard Gombotz, Richard L. Remmele, Jr.
  • LYOPHILIZED THERAPEUTIC PEPTIBODY FORMULATIONS
    Publication number: 20160143852
    Abstract: The present invention provides long-term stable formulations of a lyophilized therapeutic peptibody and methods for making a lyophilized composition comprising a therapeutic peptibody.
    Type: Application
    Filed: January 29, 2016
    Publication date: May 26, 2016
    Applicant: AMGEN INC.
    Inventors: William J. CALLAHAN, Richard L. REMMELE, Jr., Gayathri RATNASWAMY, Ramil F. LATYPOV, Dingjiang LIU
  • Lyophilized therapeutic peptibody formulations
    Patent number: 9283260
    Abstract: The present invention provides long-term stable formulations of a lyophilized therapeutic peptibody and methods for making a lyophilized composition comprising a therapeutic peptibody.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: March 15, 2016
    Assignee: AMGEN INC.
    Inventors: William J. Callahan, Richard L. Remmele, Jr., Gayathri Ratnaswamy, Ramil F. Latypov, Dingjiang Liu
  • Polypeptide Formulation
    Publication number: 20140377264
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: September 5, 2014
    Publication date: December 25, 2014
    Applicant: Immunex Corporation
    Inventors: Wayne Richard Gombotz, Richard L. Remmele, JR.
  • POLYPEPTIDE FORMULATION
    Publication number: 20120148587
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: February 21, 2012
    Publication date: June 14, 2012
    Applicant: Immunex Corporation
    Inventors: Wayne R. GOMBOTZ, Richard L. REMMELE, JR.
  • Polypeptide formulation
    Patent number: 8119604
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: February 21, 2012
    Assignee: Immunex Corporation
    Inventors: Wayne R. Gombotz, Richard L. Remmele, Jr.
  • POLYPEPTIDE FORMULATION
    Publication number: 20100086559
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: December 7, 2009
    Publication date: April 8, 2010
    Inventors: Wayne R. GOMBOTZ, Richard L. Remmele, JR.
  • Stable aqueous formulation of a soluble TNF receptor and arginine
    Patent number: 7648702
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: January 19, 2010
    Assignee: Immunex Corporation
    Inventors: Wayne R. Gombotz, Richard L. Remmele, Jr.
  • Lyophilized therapeutic peptibody Formulations
    Publication number: 20090258017
    Abstract: The present invention provides long-term stable formulations of a lyophilized therapeutic peptibody and methods for making a lyophilized composition comprising a therapeutic peptibody.
    Type: Application
    Filed: April 19, 2007
    Publication date: October 15, 2009
    Inventors: William J. Callahan, Richard L. Remmele, JR., Gayathri Ratnaswamy, Ramil F. Latypov, Dingjiang Liu
  • Increased recovery of active proteins
    Patent number: 7544784
    Abstract: The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: June 9, 2009
    Assignee: Immunex Corporation
    Inventors: Helmut M. Sassenfeld, Richard L. Remmele, Jr., Rebecca E. McCoy
  • Increased recovery of active proteins
    Patent number: 7157557
    Abstract: The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: January 2, 2007
    Assignee: Immunex Corporation
    Inventors: Helmut M. Sassenfeld, Richard L. Remmele, Jr., Rebecca E. McCoy
  • Polypeptide formulation
    Publication number: 20030180287
    Abstract: The present invention relates to an aqueous pharmaceutical composition suitable for long-term storage of polypeptides containing an Fc domain of an immunoglobulin, methods of manufacture, methods of administration and kits containing same.
    Type: Application
    Filed: February 27, 2003
    Publication date: September 25, 2003
    Applicant: Immunex Corporation
    Inventors: Wayne R. Gombotz, Richard L. Remmele
  • Increased recovery of active proteins
    Publication number: 20020182665
    Abstract: The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.
    Type: Application
    Filed: February 22, 2002
    Publication date: December 5, 2002
    Inventors: Helmut M. Sassenfeld, Richard L. Remmele, Rebecca E. McCoy