Patents by Inventor Richard L. Schilsky

Richard L. Schilsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of therapy for cancers characterized by overexpression of the HER2 receptor protein
    Publication number: 20080159981
    Abstract: Methods for treating a subject with a cancer that is characterized by overexpression of HER2 receptor protein using a combination of interleukin-2 (IL-2) or variant thereof and at least one anti-HER2 antibody or fragment thereof are provided. These anti-tumor agents are administered as two separate pharmaceutical compositions, one containing IL-2 (or variant thereof), the other containing at least one anti-HER2 antibody (or fragment thereof), according to a dosing regimen. Administering of these two agents together potentiates the effectiveness of the anti-HER2 antibody alone, resulting in a positive therapeutic response that is improved with respect to that observed with this anti-tumor agent.
    Type: Application
    Filed: August 2, 2007
    Publication date: July 3, 2008
    Inventors: Michael A. Caligiuri, Neal J. Meropol, Richard L. Schilsky
  • Methods of therapy for cancers characterized by overexpression of the HER2 receptor protein
    Patent number: 7306801
    Abstract: Methods for treating a subject with a cancer that is characterized by overexpression of HER2 receptor protein using a combination of interleukin-2 (IL-2) or variant thereof and at least one anti-HER2 antibody or fragment thereof are provided. These anti-tumor agents are administered as two separate pharmaceutical compositions, one containing IL-2 (or variant thereof), the other containing at least one anti-HER2 antibody (or fragment thereof), according to a dosing regimen. Administering of these two agents together potentiates the effectiveness of the anti-HER2 antibody alone, resulting in a positive therapeutic response that is improved with respect to that observed with this anti-tumor agent.
    Type: Grant
    Filed: May 14, 2001
    Date of Patent: December 11, 2007
    Assignees: Health Research, Inc., ARCH Development
    Inventors: Michael A. Caligiuri, Neal J. Meropol, Richard L. Schilsky
  • Methods of therapy for cancers characterized by overexpression of the HER2 receptor protein
    Publication number: 20020031515
    Abstract: Methods for treating a subject with a cancer that is characterized by overexpression of HER2 receptor protein using a combination of interleukin-2 (IL-2) or variant thereof and at least one anti-HER2 antibody or fragment thereof are provided. These anti-tumor agents are administered as two separate pharmaceutical compositions, one containing IL-2 (or variant thereof), the other containing at least one anti-HER2 antibody (or fragment thereof), according to a dosing regimen. Administering of these two agents together potentiates the effectiveness of the anti-HER2 antibody alone, resulting in a positive therapeutic response that is improved with respect to that observed with this anti-tumor agent.
    Type: Application
    Filed: May 14, 2001
    Publication date: March 14, 2002
    Inventors: Michael A. Caligiuri, Neal J. Meropol, Richard L. Schilsky