Abstract: The presently claimed and described technology provides integrated automated instruments (100, 100A, 100B, 100C) and methods (800) for automatically processing a whole blood sample (50) in a single sample tube (80). These include: mixing the sample in the tube; analyzing a portion (50P) of the mixed sample (50M); centrifuging the sample in the tube thereby separating plasma (60); and analyzing a portion (60P) of the plasma. A pretreatment module (200) may mix, centrifuge, transport, and store the sample. The integrated instrument may include multiple detector components and does not require external sample handling.

Abstract: A decapping device may be integrated with an automated biochemical analyzer or biological testing system to aid in sample testing. The exemplary decapper, includes a motor that is operable to lower a latch mechanism to engage with a cap of a sample tube and then raise the latch mechanism to remove the engaged cap. As the latch mechanism is lowered, a retractor portion also descends and causes a set of grippers to extend and grip the sample tube. As the latch mechanism is raised, the set of grippers apply a corresponding pressure to hold the sample tube in place while the cap is removed. Once removed, the cap rests within the latch mechanism and the set of grippers are retracted by the raising retractor. As the latch mechanism returns to its origin position, an ejector arm is operated causing the cap to be ejected from the latch mechanism.