Patents by Inventor Richard L Warren

Richard L Warren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8321998
    Abstract: A tensioning device that is inexpensive to manufacture and is useful for various rope tensioning applications. The rope locking device can be used anywhere along a length of rope that is being used to hold, tie down, or secure a load or item.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: December 4, 2012
    Assignee: Roto Kinetics LLC
    Inventor: Richard L. Warren
  • Publication number: 20110061208
    Abstract: The present invention is a tensioning device that is inexpensive to manufacture and is useful for various rope tensioning applications. The rope locking device according to the present invention can be used anywhere along a length of rope that is being used to hold, tie down, or secure a load or item.
    Type: Application
    Filed: September 14, 2009
    Publication date: March 17, 2011
    Inventor: Richard L. WARREN
  • Patent number: 7422749
    Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: September 9, 2008
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Michael T. Black, Martin K. Burnham, Jason C. Fedon, John E. Hodgson, David J. Knowles, Michael A. Lonetto, Richard O. Nicholas, Leslie M. Palmer, Julie M. Pratt, Raymond W. Reichard, Martin Rosenberg, Christopher M. Traini, Judith Ward, Richard L. Warren
  • Patent number: 6511839
    Abstract: The invention provides fucose kinase promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: January 28, 2003
    Inventors: Pan Fong Chan, Sanjoy Biswas, David J. Holmes, Michael A. Lonetto, Leslie M. Palmer, Stephanie Van Horn, Richard L. Warren, Jr., Magdalena Zalacain
  • Patent number: 6444445
    Abstract: Live Brucella vaccines and methods for preparing the live vaccines protective against brucellosis are described. The vaccines are prepared by introducing a deletion in the rfbU gene of a strain of Brucella which results in attenuation of the strain while retaining the desired immunogenicity to initiate a protective immunogenic response. Other strains with varying levels of attenuation are described.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: September 3, 2002
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Mikeljon P. Nikolich, David L. Hoover, Richard L. Warren, Luther E. Lindler, Ted L. Hadfield, Gerhardt G. Schurig, Stephen M. Boyle, John R. McOulston, Nammalwar Sriranganathan
  • Publication number: 20020119511
    Abstract: The invention provides dnaE polypeptides and polynucleotides encoding dnaE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing dnaE polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 29, 2002
    Inventors: Earl May, Stephanie Van Horn, Patrick V. Warren, Richard L. Warren
  • Publication number: 20020115191
    Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 22, 2002
    Inventors: John P. Throup, Stephanie Van Horn, Richard L. Warren, David J. Holmes, Alison F. Chalker, Chi Young So, Karen A. Ingraham
  • Publication number: 20020107217
    Abstract: The invention provides galK promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
    Type: Application
    Filed: September 17, 2001
    Publication date: August 8, 2002
    Inventors: Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Stephanie Van Horn, Richard L. Warren, Magdalena Zalacain
  • Patent number: 6406889
    Abstract: The invention provides 509HK polypeptides and polynucleotides encoding 509HK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing 509HK polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: June 18, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Weonhye Bae, Sanjoy Biswas, Martin K. R. Burnham, John P. Throup, Stephanie Van Horn, Richard L. Warren, Jr.
  • Publication number: 20020058796
    Abstract: The invention provides def1 polypeptides and polynucleotides encoding def1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def1 polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 21, 2001
    Publication date: May 16, 2002
    Inventors: Michael A. Lonetto, David J. Holmes, Deborah D. Jaworski, Richard O. Nicholas, Min Wang, Robert K. Stodola, Anna L. Kosmatka, Richard L. Warren, David J.C. Knowles, Christopher M. Traini, John E. Hodgson
  • Patent number: 6316237
    Abstract: The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: November 13, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: Thomas B Mathie, Christopher M Traini, Stephanie Van Horn, Richard L Warren
  • Patent number: 6291230
    Abstract: The invention provides galK promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: September 18, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc,
    Inventors: Magdalena Zalacain, Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Stephanie Van Horn, Richard L. Warren, Jr.
  • Patent number: 6280990
    Abstract: The invention provides dnaE polypeptides and polynucleotides encoding dnaE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing dnaE polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: August 28, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Earl May, Stephanie Van Horn, Patrick V Warren, Richard L Warren
  • Patent number: 6277597
    Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: August 21, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Chi Young So, John P Throup, Stephanie Van Horn, Richard L Warren
  • Publication number: 20010014673
    Abstract: Live Brucella vaccines and methods for preparing the live vaccines protective against brucellosis are described. The vaccines are prepared by introducing a deletion in the rfbU gene of a strain of Brucella which results in attenuation of the strain while retaining the desired immunogenicity to initiate a protective immunogenic response. Other strains with varying levels of attenuation are described.
    Type: Application
    Filed: January 22, 1998
    Publication date: August 16, 2001
    Inventors: MIKELJON P. NIKOLICH, DAVID L. HOOVER, RICHARD L. WARREN, LUTHER E. LINDLER, TED L. HADFIELD, CERHARDT G. SCHURIG, STEPHEN M. BOYLE, JOHN R. MCOULSTON, NAMMALWAR SRIRANGANATHAN
  • Patent number: 6204014
    Abstract: The invention provides DnaB polypeptides and polynucleotides encoding DnaB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing DnaB polypeptides to screen for anibacterial compounds.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: March 20, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Deborah D Jaworski, Anna L Lenox, Earl W May, Marie J Mazzulla, Jennifer Ray, Min Wang, Richard L Warren, Jr.
  • Patent number: 6146846
    Abstract: The invention provides priA polypeptides and polynucleotides encoding priA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing priA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: November 14, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Damien McDevitt, Lisa K Shilling, Annemarie St. John, Richard L Warren
  • Patent number: 6117640
    Abstract: A recombinant protein encompassing a C-terminal protion from the structural envelope glycoprotein and an N-terminal portion from non-structural protein one of dengue type 2 virus was expressed in Escherichia coli as a fusion protein with Staphylococcal protein A. The recombinant protein was found to provide protection against lethal challenge with dengue 2 in mice.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: September 12, 2000
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Ashok Kumar Srivastava, J. Robert Putnak, Charles H. Hoke, Richard L. Warren
  • Patent number: 6117662
    Abstract: The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: September 12, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Thomas B Mathie, Christopher M Traini, Stephanie Van Horn, Richard L Warren
  • Patent number: 5939075
    Abstract: The vaccines are prepared by isolating the Brucella genes complementing mutations in the purEK genes of Escherichia coli, physically mapping, determining the DNA sequence, constructing a defined deletion mutation by polynucleotide chain reaction (PCR), introducing a selectable marker into the deletion, and then selecting a purE mutant in Brucella arising by allelic exchange. The resulting Brucella require purines for growth because they lack the purE gene product that is required for the carboxylation of 5'-phosphoribosyl-5-aminoimidazole.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: August 17, 1999
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Huo-shu H. Houng, Richard L. Warren