Patents by Inventor Richard L Warren
Richard L Warren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8321998Abstract: A tensioning device that is inexpensive to manufacture and is useful for various rope tensioning applications. The rope locking device can be used anywhere along a length of rope that is being used to hold, tie down, or secure a load or item.Type: GrantFiled: September 14, 2009Date of Patent: December 4, 2012Assignee: Roto Kinetics LLCInventor: Richard L. Warren
-
Publication number: 20110061208Abstract: The present invention is a tensioning device that is inexpensive to manufacture and is useful for various rope tensioning applications. The rope locking device according to the present invention can be used anywhere along a length of rope that is being used to hold, tie down, or secure a load or item.Type: ApplicationFiled: September 14, 2009Publication date: March 17, 2011Inventor: Richard L. WARREN
-
Patent number: 7422749Abstract: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.Type: GrantFiled: January 25, 2007Date of Patent: September 9, 2008Assignee: Affinium Pharmaceuticals, Inc.Inventors: Michael T. Black, Martin K. Burnham, Jason C. Fedon, John E. Hodgson, David J. Knowles, Michael A. Lonetto, Richard O. Nicholas, Leslie M. Palmer, Julie M. Pratt, Raymond W. Reichard, Martin Rosenberg, Christopher M. Traini, Judith Ward, Richard L. Warren
-
Patent number: 6511839Abstract: The invention provides fucose kinase promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.Type: GrantFiled: June 9, 2000Date of Patent: January 28, 2003Inventors: Pan Fong Chan, Sanjoy Biswas, David J. Holmes, Michael A. Lonetto, Leslie M. Palmer, Stephanie Van Horn, Richard L. Warren, Jr., Magdalena Zalacain
-
Patent number: 6444445Abstract: Live Brucella vaccines and methods for preparing the live vaccines protective against brucellosis are described. The vaccines are prepared by introducing a deletion in the rfbU gene of a strain of Brucella which results in attenuation of the strain while retaining the desired immunogenicity to initiate a protective immunogenic response. Other strains with varying levels of attenuation are described.Type: GrantFiled: January 22, 1998Date of Patent: September 3, 2002Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Mikeljon P. Nikolich, David L. Hoover, Richard L. Warren, Luther E. Lindler, Ted L. Hadfield, Gerhardt G. Schurig, Stephen M. Boyle, John R. McOulston, Nammalwar Sriranganathan
-
Publication number: 20020119511Abstract: The invention provides dnaE polypeptides and polynucleotides encoding dnaE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing dnaE polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: August 9, 2001Publication date: August 29, 2002Inventors: Earl May, Stephanie Van Horn, Patrick V. Warren, Richard L. Warren
-
Publication number: 20020115191Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: August 9, 2001Publication date: August 22, 2002Inventors: John P. Throup, Stephanie Van Horn, Richard L. Warren, David J. Holmes, Alison F. Chalker, Chi Young So, Karen A. Ingraham
-
Publication number: 20020107217Abstract: The invention provides galK promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.Type: ApplicationFiled: September 17, 2001Publication date: August 8, 2002Inventors: Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Stephanie Van Horn, Richard L. Warren, Magdalena Zalacain
-
Patent number: 6406889Abstract: The invention provides 509HK polypeptides and polynucleotides encoding 509HK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing 509HK polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 4, 2000Date of Patent: June 18, 2002Assignee: SmithKline Beecham CorporationInventors: Weonhye Bae, Sanjoy Biswas, Martin K. R. Burnham, John P. Throup, Stephanie Van Horn, Richard L. Warren, Jr.
-
Publication number: 20020058796Abstract: The invention provides def1 polypeptides and polynucleotides encoding def1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing def1 polypeptides to screen for antibacterial compounds.Type: ApplicationFiled: May 21, 2001Publication date: May 16, 2002Inventors: Michael A. Lonetto, David J. Holmes, Deborah D. Jaworski, Richard O. Nicholas, Min Wang, Robert K. Stodola, Anna L. Kosmatka, Richard L. Warren, David J.C. Knowles, Christopher M. Traini, John E. Hodgson
-
Patent number: 6316237Abstract: The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 26, 2000Date of Patent: November 13, 2001Assignee: SmithKline Beecham Corp.Inventors: Thomas B Mathie, Christopher M Traini, Stephanie Van Horn, Richard L Warren
-
Patent number: 6291230Abstract: The invention provides galK promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.Type: GrantFiled: June 16, 2000Date of Patent: September 18, 2001Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc,Inventors: Magdalena Zalacain, Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Stephanie Van Horn, Richard L. Warren, Jr.
-
Patent number: 6280990Abstract: The invention provides dnaE polypeptides and polynucleotides encoding dnaE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing dnaE polypeptides to screen for antibacterial compounds.Type: GrantFiled: August 31, 1999Date of Patent: August 28, 2001Assignee: SmithKline Beecham CorporationInventors: Earl May, Stephanie Van Horn, Patrick V Warren, Richard L Warren
-
Patent number: 6277597Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.Type: GrantFiled: August 3, 1999Date of Patent: August 21, 2001Assignee: SmithKline Beecham CorporationInventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Chi Young So, John P Throup, Stephanie Van Horn, Richard L Warren
-
Publication number: 20010014673Abstract: Live Brucella vaccines and methods for preparing the live vaccines protective against brucellosis are described. The vaccines are prepared by introducing a deletion in the rfbU gene of a strain of Brucella which results in attenuation of the strain while retaining the desired immunogenicity to initiate a protective immunogenic response. Other strains with varying levels of attenuation are described.Type: ApplicationFiled: January 22, 1998Publication date: August 16, 2001Inventors: MIKELJON P. NIKOLICH, DAVID L. HOOVER, RICHARD L. WARREN, LUTHER E. LINDLER, TED L. HADFIELD, CERHARDT G. SCHURIG, STEPHEN M. BOYLE, JOHN R. MCOULSTON, NAMMALWAR SRIRANGANATHAN
-
Patent number: 6204014Abstract: The invention provides DnaB polypeptides and polynucleotides encoding DnaB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing DnaB polypeptides to screen for anibacterial compounds.Type: GrantFiled: November 13, 1998Date of Patent: March 20, 2001Assignee: SmithKline Beecham CorporationInventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Deborah D Jaworski, Anna L Lenox, Earl W May, Marie J Mazzulla, Jennifer Ray, Min Wang, Richard L Warren, Jr.
-
Patent number: 6146846Abstract: The invention provides priA polypeptides and polynucleotides encoding priA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing priA polypeptides to screen for antibacterial compounds.Type: GrantFiled: April 27, 1998Date of Patent: November 14, 2000Assignee: SmithKline Beecham CorporationInventors: Damien McDevitt, Lisa K Shilling, Annemarie St. John, Richard L Warren
-
Patent number: 6117640Abstract: A recombinant protein encompassing a C-terminal protion from the structural envelope glycoprotein and an N-terminal portion from non-structural protein one of dengue type 2 virus was expressed in Escherichia coli as a fusion protein with Staphylococcal protein A. The recombinant protein was found to provide protection against lethal challenge with dengue 2 in mice.Type: GrantFiled: May 2, 1995Date of Patent: September 12, 2000Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ashok Kumar Srivastava, J. Robert Putnak, Charles H. Hoke, Richard L. Warren
-
Patent number: 6117662Abstract: The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 12, 1999Date of Patent: September 12, 2000Assignee: SmithKline Beecham CorporationInventors: Thomas B Mathie, Christopher M Traini, Stephanie Van Horn, Richard L Warren
-
Patent number: 5939075Abstract: The vaccines are prepared by isolating the Brucella genes complementing mutations in the purEK genes of Escherichia coli, physically mapping, determining the DNA sequence, constructing a defined deletion mutation by polynucleotide chain reaction (PCR), introducing a selectable marker into the deletion, and then selecting a purE mutant in Brucella arising by allelic exchange. The resulting Brucella require purines for growth because they lack the purE gene product that is required for the carboxylation of 5'-phosphoribosyl-5-aminoimidazole.Type: GrantFiled: May 8, 1997Date of Patent: August 17, 1999Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Huo-shu H. Houng, Richard L. Warren