Patents by Inventor Richard Laga

Richard Laga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ
    Publication number: 20230381112
    Abstract: An amphiphilic block copolymer having any one of the formulas D-S—H, S(D)-H, S—H(D), D-S—H—S, D-S—H—S-D, S(D)-H—S, S(D)-H—S(D) or S—H(D)-S is disclosed. S is a hydrophilic block; H is a hydrophobic block; D is a drug molecule; ( ) denotes that the group is bonded directly or indirectly as a side chain or as part of a side chain group to the adjacent group; and the hyphen, “-” (or sometimes “-”), denotes that each of the adjacent S, H or D are linked either directly to one another or indirectly to one another via a linker, additionally wherein the hydrophilic block comprises a first hydrophilic monomer and the hydrophobic block comprises a first hydrophobic monomer and a second hydrophobic monomer.
    Type: Application
    Filed: September 21, 2021
    Publication date: November 30, 2023
    Applicants: Vaccitech North America, Inc., Institute of Macromolecular Chemistry
    Inventors: Geoffrey Martin Lynn, David Robert Wilson, Ellen Wang, Kyle James Fergie, Lucie Woldrichová, Ladislav Androvic, Richard Laga
  • Compositions and Methods of Manufacturing Star Polymers for Ligand Display and/or Drug Delivery
    Publication number: 20230026627
    Abstract: A star polymer of formula O[P1]-([X]-A[P2]-[Z]-[P3])n where O is a core; A is a polymer arm attached to the core; X is a linker molecule between the core and the polymer arm; Z is a linker molecule between the end of the polymer arm and P3; P1, P2 and P3 are each independently one or more pharmaceutically active compounds that act extracellularly or intracellularly, n is an integer number; [ ] denotes that the group is optional; and at least one of P1, P2 or P3 is present.
    Type: Application
    Filed: April 16, 2020
    Publication date: January 26, 2023
    Applicants: Vaccitech North America, Inc., Institute of Macromolecular Chemistry, The United States of America, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Geoffrey Lynn, Yaling Zhu, Jacob Holechek, David Wilson, Joe Francica, Richard Laga, Gabriela Muzíková
  • POLYMER ADJUVANT
    Publication number: 20210000934
    Abstract: The invention relates to an adjuvant comprising Pattern Recognition Receptor (PRR) agonist molecules linked to polymer chains that are capable of undergoing particle formation in aqueous conditions, or in aqueous conditions in response to external stimuli; and methods of treatment or prevention of disease using such an adjuvant.
    Type: Application
    Filed: June 22, 2020
    Publication date: January 7, 2021
    Applicants: Oxford University Innovation Limited, The U.S.A., as Represented by the Secretary, Department of Health and Human Services
    Inventors: Kerry Fisher, Richard Laga, Geoffrey Lynn, Leonard Seymour, Robert Seder
  • POLYMER ADJUVANT
    Publication number: 20170304420
    Abstract: The invention relates to an adjuvant comprising Pattern Recognition Receptor (PRR) agonist molecules linked to polymer chains that are capable of undergoing particle formation in aqueous conditions, or in aqueous conditions in response to external stimuli; and methods of treatment or prevention of disease using such an adjuvant.
    Type: Application
    Filed: October 9, 2015
    Publication date: October 26, 2017
    Applicants: Oxford University Innovation Limited, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV
    Inventors: Kerry Fisher, Richard Laga, Geoffrey Lynn, Leonard Seymour, Robert Seder