Abstract: The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.

Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.

Abstract: Features described herein generally relate to enhancing functionality of electronic devices. Particularly, a notification is received from a wearable device that includes a position of the wearable device within an area, a determination is made that the wearable device is located within a predetermined distance from a controllable device, a graphical user interface page that includes buttons is sent to the wearable device, an indication that a button of the buttons has been activated is received from the wearable device, and a command signal that includes an instruction is sent to the controllable device. In this way, functionality of electronic devices can be extended with wearable devices.

Abstract: This disclosure describes techniques for allowing an organization to manage user identities. In some examples, the management of user identities may be serverless. In some examples, serverless identity management may be enabled through a distributed application on user devices of the organization. The application may generate and/or store information related to the user identities on the user devices. Serverless identity management may further include storing at least some of the information at a location that is easily accessible to the user devices, such as a cloud computing location, while maintaining security for private data. Serverless identity management may therefore provide an organization with greater operational flexibility.

Abstract: A volatile composition dispenser comprises a volatile composition container comprising at least one volatile composition therein. A rupture element is positioned proximate to the volatile composition container. The volatile composition container comprises a cam comprising a camming surface. The camming surface is configured to move at least a portion of the rupture element toward the volatile composition container to puncture the volatile composition container and release at least a portion of the volatile composition from the volatile composition container such that the portion of the volatile composition evaporates and exits the volatile composition dispenser.

Abstract: A method and device for a UE-to-UE relay are disclosed. In one embodiment, the UE-to-UE relay establishes a first PC5 Radio Resource Control (RRC) connection with a first remote User Equipment (UE) and establishes a second PC5 RRC connection with a second remote UE to support communication between the first remote UE and the second remote UE via the UE-to-UE relay. The UE-to-UE relay also transmits a first RRC message to a network node to request sidelink transmission resource, wherein the first RRC message includes an identity (ID) of the first remote UE and at least one of following information: a destination ID of the second remote UE, an ID of a Sidelink (SL) Data Radio Bearer (DRB), a third ID of a PC5 quality of service (QoS) flow, and a PC5 QoS profile of the PC5 QoS flow.

Abstract: A method and device are disclosed from the perspective of a first User Equipment (UE) to perform a PC5 unicast link establishment procedure. In one embodiment, the method includes the first UE transmitting a first PC5-S message for establishing a PC5 unicast link with a UE-to-UE Relay, wherein the PC5-S message includes a Layer-2 Identity (ID) of a second UE. The method further includes the first UE receiving a second PC5-S message from the UE-to-UE Relay, wherein the second PC5-S message is transmitted by the UE-to-UE Relay in response to reception of the first PC5-S message.

Abstract: The present embodiments provide compounds and methods for targeting cells expressing GLP-1 receptor.

Abstract: Methods for characterizing spillover spreading originating from a first fluorochrome in fluorescent flow cytometer data collected for a second fluorochrome are provided. In some embodiments, methods include partitioning the fluorescent flow cytometer data according to the intensity of the data relative to the first fluorochrome. In embodiments, methods also include estimating with a first linear regression a zero-adjusted standard deviation for the intensity of light collected from the second fluorochrome for each of the partitioned quantiles based on the assumption that the intensity of light collected from the first fluorochrome is zero, and obtaining with a second linear regression a spillover spreading coefficient from the zero-adjusted standard deviations. Systems and computer-readable media for characterizing spillover spreading originating from a first fluorochrome in fluorescent flow cytometer data collected for a second fluorochrome are also provided.

Abstract: A product delivery system includes a product transport vehicle having at least a plurality of tank compartments, internal valves, control valves, fluid property sensors, temperature sensors, overfill sensors, pressure sensors, a system controller, and a memory module. The product delivery system may be operable to communicatively connect with the loading system at a loading station, a fleet management system, or a cloud system to obtain information, such as the amount of liquid product to be loaded into a tank compartment. The product delivery system may be operable to compare the volumes of the tank compartments with the amounts of liquid product to be loaded at a loading station and maintain the internal valve or control valve in a locked state or transition the internal valve or control valve to an unlocked state based on the comparison. Other comparisons based on liquid type or distribution tank volume can also be made.

Abstract: A digital measuring device implemented on a photonic integrated circuit, the digital measuring device including a laser source implemented on the photonic integrated circuit configured to provide light, a first waveguide structure implemented on the photonic integrated circuit configured to direct a first portion of light from the laser source at a moving object and receive light reflected from the moving object, a second waveguide structure implemented on the photonic integrated circuit configured to combine a second portion of light from the laser source with the light reflected from the moving object to produce a measurement beam, a first multiplexer implemented on the photonic integrated circuit configured to split the measurement beam into a plurality of channels, and a plurality of detectors implemented on the photonic integrated circuit configured to detect an intensity value of each channel to measure a distance between the digital measuring device and the moving object.

Abstract: A lid for use with a frying pan, or any pan. The lid has multiple embodiments, such as, directing cooking smoke and odor into under-performing range hoods and downdraft systems. Purchasing new exhaust systems are expensive with little or no guarantees from any manufacturer that their system will remove all cooking smoke. The current invention may be purchased at a fraction of the cost, and will also guarantee total smoke exhaustion. The current invention directs all harmful chemicals emitted from inside a pan, and from stovetop burners, into an exhaust system so they are removed from the home. The invention protects humans and animals from breathing harmful chemicals into their lungs. It protects against kitchen fires, regulates the cooking temperature inside the pan, and allows self-basting of food. The current invention is made from FDA food grade approved material, and is dishwater safe.

Abstract: A monitoring system includes a weight sensor for receiving a vial containing a controlled substance possessed by a patient. A processor receives a weight measured by the weight sensor. A communication circuit transmits the weight measured by the weight sensor to a remote server. The weight sensor may be mounted in a container having a first compartment and a second compartment. The first compartment has a first lid that is releasable without any lock. A second compartment has a second lid that is secured by a lock. The weight sensor is mounted inside the second compartment.

Abstract: Provided herein are specific inhibitors, compositions, methods and uses for reducing expression of COASY in a cell or individual. Such specific inhibitors, compositions, and methods are useful to treat a liver disease or disorder, including but not limited to NASH, in a subject.

Abstract: A digital measuring device implemented on a photonic integrated circuit, the digital measuring device including a laser source implemented on the photonic integrated circuit configured to provide light, a first waveguide structure implemented on the photonic integrated circuit configured to direct a first portion of light from the laser source at a moving object and receive light reflected from the moving object, a second waveguide structure implemented on the photonic integrated circuit configured to combine a second portion of light from the laser source with the light reflected from the moving object to produce a measurement beam, a first multiplexer implemented on the photonic integrated circuit configured to split the measurement beam into a plurality of channels, and a plurality of detectors implemented on the photonic integrated circuit configured to detect an intensity value of each channel to measure a distance between the digital measuring device and the moving object.

Abstract: Techniques, systems, and methods are disclosed to generate messaging to view content on media devices based on predictive factors. Information may be received to trigger one or more predictive factors and then generate a candidate set of offers to view content at a media device based on the information. Based on the one or more predictive factors, confidence values may be determined for each offer in the candidate set of offers. The candidate set of offers may be ranked based on the associated confidence values. Subsequently, presentation of at least one offer of the candidate set of offers may be caused to display in a user interface screen on the media device based on the ranking.

Abstract: Provided according to embodiments of the invention are methods of forming a lipstatin derivative, (S)-1-((2S,3S)-3-ethyl-4-oxooxetan-2-yl) tridecan-2-yl formyl-L-alaninate. Such methods include one or more reaction steps that include the Mitsunobu coupling of N-formyl L-alanine in the presence of di-t-butyl azodicarboxylate (DBAD) and triphenylphosphine. Compounds formed by a method of the invention, compositions that include a compound formed by a method of the invention, and methods of inhibiting lipase activity and/or treating pancreatitis using a compound formed by a method of the invention are also provided.

Abstract: A detonation module for a perforation tool is described herein. The detonation module includes a detonator, a switch circuit disposed in a fluid-sealed housing and electrically coupled to the detonator, a shielding circuit coupled to the switch circuit, an annular electrical contact electrically coupled to the switch circuit, and an annular, electrically conductive, compressive member to form a compressive electrical connection with an end of a perforation unit.

Abstract: A dishwasher has a chassis, at least one spray nozzle, a dish rack, a closure and at least one loading zone marker. The chassis has a base and forms a tub. The tub at least partially defines a treating chamber. The at least one spray nozzle is configured to exhaust a flow of treating fluid into the treating chamber. The dish rack is provided within the treating chamber. The closure is moveably coupled to the base.

Abstract: Embodiments are directed to data processing. A plurality of fact objects and a plurality of attribute objects may be provided such that each of the attribute objects may be associated with one or more fact objects. A fact key may be generated for each of the plurality of fact objects based on information associated with each fact object. Attribute objects associated with each of the plurality of fact objects may be determined based on attribute information associated with each fact object. An attribute key for each of the one or more attribute objects may be generated based on the attribute information. The attribute keys and a plurality of fact keys may be stored at a plurality of storage locations in a data catalog such that each storage location corresponds to one of the plurality of fact keys.