Patents by Inventor Richard Lenz
Richard Lenz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240083042Abstract: The present invention relates to a device for gripping a flat structure with openings in the area of its upper side, in particular a honeycomb structure, comprising two gripper units spaced apart from each other in a length direction, each of which in turn comprises at least one pin, and at least one pin displacement unit which is adapted to displace the at least one pin in an extending direction, as well as a tilting unit which is adapted to tilt at least one of the gripper units about a tilting axis extending substantially in a width direction. The invention also relates to a method for gripping a flat structure by means of such a device.Type: ApplicationFiled: September 12, 2023Publication date: March 14, 2024Applicant: Cevotec GmbHInventors: David Woods, Richard Carle, Florian Lenz
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Patent number: 10563170Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.Type: GrantFiled: April 17, 2018Date of Patent: February 18, 2020Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Patent number: 10226041Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.Type: GrantFiled: August 17, 2017Date of Patent: March 12, 2019Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Publication number: 20180237747Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.Type: ApplicationFiled: April 17, 2018Publication date: August 23, 2018Applicant: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Patent number: 9976119Abstract: The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: GrantFiled: May 17, 2016Date of Patent: May 22, 2018Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Publication number: 20170367324Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.Type: ApplicationFiled: August 17, 2017Publication date: December 28, 2017Applicant: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Patent number: 9781919Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.Type: GrantFiled: January 18, 2016Date of Patent: October 10, 2017Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Publication number: 20160257929Abstract: The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: ApplicationFiled: May 17, 2016Publication date: September 8, 2016Applicant: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Patent number: 9347039Abstract: Generally, compositions and methods for handling processed sperm populations including samples that are freshly collected, transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a healthy embryo and produce a healthy offspring. The novel compounds described can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: GrantFiled: March 15, 2013Date of Patent: May 24, 2016Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Patent number: 9347040Abstract: The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: GrantFiled: March 15, 2013Date of Patent: May 24, 2016Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Patent number: 9347038Abstract: The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: GrantFiled: June 1, 2012Date of Patent: May 24, 2016Assignee: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Publication number: 20160128320Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.Type: ApplicationFiled: January 18, 2016Publication date: May 12, 2016Applicant: Inguran, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Publication number: 20160010057Abstract: Embodiments of the claimed invention relate to a method of producing sex sorted sperm having an improved dose response which includes the steps of extending a sperm sample with a buffering holding media and adjusting the concentration of the extended sperm sample to a target concentration range. The extended sperm may then be stained with a DNA selective dye and sex sorted with a flow cytometer into a catch fluid. During the extending and sorting of the sperm sample, the pH may be maintained at a target pH. Additionally, at least one of the buffering holding media, the DNA selective dye and the catch fluid may be supplemented with at least one antioxidant.Type: ApplicationFiled: September 22, 2015Publication date: January 14, 2016Applicant: INGURAN, LLCInventors: Ramakrishnan Vishwanath, Kenneth Michael Evans, Thomas B. Gilligan, Juan Moreno, Richard Lenz, Clara Gonzalez-Marin
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Publication number: 20140099627Abstract: Methods for processing and sorting sperm are disclosed. Portions of sperm sorting or staining processes may include standardizing sperm samples by adjusting the concentration of the sperm sample to a predetermined concentration and adjusting the pH of the sample to a predetermined value. Sperm may also be stained in a single staining buffer having a DNA selective dye and a quenching dye.Type: ApplicationFiled: March 4, 2013Publication date: April 10, 2014Applicant: INGURAN, LLCInventors: Thomas Boyd Gilligan, Kenneth Michael Evans, Richard Lenz, Clara Gonzalez-Marin, Ramakrishnan Vishwanath
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Publication number: 20130309651Abstract: The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: ApplicationFiled: March 15, 2013Publication date: November 21, 2013Applicant: INGURAN, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Publication number: 20130183656Abstract: The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.Type: ApplicationFiled: June 1, 2012Publication date: July 18, 2013Applicant: INGURAN, LLCInventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
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Use of genes identified to be involved in tumor development for the development of anti-cancer drugs
Publication number: 20040033974Abstract: The invention relates to the use of inhibitors of the expressed proteins of the murine genes and/or their human homologues listed in Table 1 for the preparation of a therapeutical composition for the treatment of cancer, in particular for the treatment of solid tumors of lung, colon, breast, prostate, ovarian, pancreas and leukemia. The invention also relates to the therapeutical compositions comprising the inhibitors and to methods for development of the inhibitor compounds.Type: ApplicationFiled: August 19, 2002Publication date: February 19, 2004Applicant: Kylix B.V.Inventors: Anders Henrik Lund, Antonius Jozef Maria Berns, Maarten Matthijs Sharif Van Lohuizen, Carla Pedro Martins, Henricus Martinus Maria Mikkers, Jack Richard Lenz