Patents by Inventor RICHARD LEROUX
RICHARD LEROUX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240010677Abstract: The tetrapeptide has the general Formula X-LLAN-Z wherein at the N-terminal end X is selected from H, —CO—R1, —SO2—R1 or a biotinoyl group, at the C-terminal end Z is selected from OH, OR1, NH2, NHR1 or NR1R2, and R1 and R2 are selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy, saccharide and aryloxy, said group having from 1 to 24 carbon atoms. A preferred peptide is the Pal-LLAN. This tetrapeptide can stimulate the synthesis of molecules constituting the dermal extracellular matrix, in particular collagen 1 and fibrilin 1, and can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the skin mechanical properties, firmness/tone/elasticity/flexibility, to increase skin density and volume, for a restructuring effect and/or to fight against stretch marks, and skin sagging. The peptide is also adapted to stimulate hair growth.Type: ApplicationFiled: November 15, 2021Publication date: January 11, 2024Applicant: SedermaInventors: Philippe Mondon, Olivier Peschard, Richard Leroux
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Publication number: 20230398049Abstract: They have the general Formula X-(Xaa)nLE(Xaa)m-Z wherein Xaa is selected from L, K, E and D, either n=2 and m=0, or n=1 and m=1, at the N-terminal end X being selected from H, —CO—R1, —SO2-R1 or a biotinoyl group, at the C-terminal end Z being selected from OH, OR1, NH2, NHR1 or NR1R2, and R1 and R2 being selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy, saccharide and aryloxy, said group having from 1 to 24 carbon atoms. Preferred peptide sequences are X-LKLE-Z and X-ELED-Z. These tetrapeptides stimulate the synthesis of molecules constituting the ECM, in particular collagen 1 and 4, hyaluronic acid and fibronectin, and can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the skin mechanical properties, to increase skin density and volume, hydration, and/or to fight against stretch marks, and skin sagging.Type: ApplicationFiled: November 17, 2021Publication date: December 14, 2023Applicant: SedermaInventors: Philippe Mondon, Olivier Peschard, Richard Leroux
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Publication number: 20230399359Abstract: They have the general Formula X-(Xaa)nPG(Xaa)m-Z wherein Xaa is either A or V, either n=2 and m=0, or n=1 and m=1, at the N-terminal end X being selected from H, —CO—R1, —SO2—R1 or a biotinyl group, at the C-terminal end Z being selected from OH, OR1, NH2, NHR1 or NR1R2, and R1 and R2 being selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy, saccharide and aryloxy, said group having from 1 to 24 carbon atoms. Preferred peptide sequences are X-AVPG-Z and X-VPGA-Z. These tetrapeptides stimulate the synthesis of molecules constituting the dermal extracellular matrix, in particular collagen 1 and 4 and fibronectin, and can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the skin mechanical properties, firmness/tone/elasticity/flexibility, to increase skin density and volume, for a restructuring effect and/or to fight against stretch marks, and skin sagging.Type: ApplicationFiled: November 15, 2021Publication date: December 14, 2023Applicant: SedermaInventors: Philippe Mondon, Olivier Peschard, Richard Leroux
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Publication number: 20230383646Abstract: A technique facilitates monitoring of events related to various well operations. According to an embodiment, the technique provides a non-invasive approach to measuring fluid and solids transport through well surface pipe assemblies. The desired information may be detected and obtained by mounting sensors to the exterior of pipes, thus enabling retrofitting of the sensor system to existing assemblies at a desired time during a given operation. Additionally, the technique may utilize a combination of sensors and systems for measuring fluid and solids transport through well flow path assemblies. The measurements obtained may be used to provide real-time monitoring of surface flow conditions as well as of downhole wellbore conditions and of the status of downhole equipment.Type: ApplicationFiled: October 6, 2021Publication date: November 30, 2023Inventors: Wai Sum Wilson Yip, Courtney Payne, Sascha Trummer, Sergio Alberto Rondon Fajardo, Ryan Richard Leroux
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Patent number: 11612556Abstract: The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid. The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.Type: GrantFiled: December 14, 2015Date of Patent: March 28, 2023Assignee: SedermaInventors: Olivier Peschard, Anne Doucet, Richard Leroux, Philippe Mondon
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Patent number: 11001607Abstract: The peptide has from 3 to 10 amino acids comprising at least the sequence K*(Ac)GH or K*(Ac)HG and may further comprise an N-terminus modification, preferably an acylation, and/or a C-terminus modification; K* is selected from the group consisting of lysine, ornithine, diaminobutyric acid, diaminopropionic acid and a hydroxylated derivative thereof; K*(Ac) corresponds to a lysine, ornithine, diaminobutyric acid, diaminopropionic acid or a hydroxylated derivative thereof, acetylated on the amine of their lateral hydrocarbon chain. The two preferred peptides are Pal-K(Ac)GH and Pal-K(Ac)HG. This peptide can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the mechanical properties of the skin, firmness/tonicity/elasticity/flexibility, to increase the density and volume of the skin, for a restructuring, healing effect, and/or to fight stretch marks.Type: GrantFiled: June 13, 2017Date of Patent: May 11, 2021Assignee: SedermaInventors: Olivier Peschard, Anne Doucet, Richard Leroux, Philippe Mondon
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Patent number: 10668000Abstract: The peptides have the general following formula: X-Pro*-Pro*-Xaa-Y in which: •Xaa is selected from Leucine (Leu, L), Arginine (Arg, R), Lysine (Lys, K), Alanine (Ala, A), Serine (Ser, S), and Aspartic acid (Asp, D); •At the N terminal end of the peptide, X is selected from H, —CO—R1 and —SO2—R1; •At the C terminal end of the peptide, Y is selected from OH, OR1, NH2, NHR1 and NR1R2; •R1 and R2 are, independently from each other, selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy and aryloxy group, that can be linear, branched, cyclic, poly-cyclic, non-saturated, hydroxylated, carbonylated, phosphorylated and/or sulfured, and which skeletum can comprise an heteroatom, in particular an O, S and/or N atom; •Pro* correspond to a Proline, an analogue or derivative thereof; •if X is H then Y is selected from OR1, NH2, NHR1 and NR1R2, and if Y is OH then X is —CO— or —SO2—R1; and the peptide hypoxanthine-Pro-Pro-Arg being excluded.Type: GrantFiled: May 21, 2015Date of Patent: June 2, 2020Assignee: SEDERMAInventors: Olivier Peschard, Anne Doucet, Richard Leroux, Philippe Mondon
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Publication number: 20190153030Abstract: The peptide has from 3 to 10 amino acids comprising at least the sequence K*(Ac)GH or K*(Ac)HG and may further comprise an N-terminus modification, preferably an acylation, and/or a C-terminus modification; K* is selected from the group consisting of lysine, ornithine, diaminobutyric acid, diaminopropionic acid and a hydroxylated derivative thereof; K*(Ac) corresponds to a lysine, ornithine, diaminobutyric acid, diaminopropionic acid or a hydroxylated derivative thereof, acetylated on the amine of their lateral hydrocarbon chain. The two preferred peptides are Pal-K(Ac)GH and Pal-K(Ac)HG. This peptide can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the mechanical properties of the skin, firmness/tonicity/elasticity/flexibility, to increase the density and volume of the skin, for a restructuring, healing effect, and/or to fight stretch marks.Type: ApplicationFiled: June 13, 2017Publication date: May 23, 2019Applicant: SedermaInventors: Olivier Peschard, Anne Doucet, Richard Leroux, Philippe Mondon
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Publication number: 20180000717Abstract: The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid. The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.Type: ApplicationFiled: December 14, 2015Publication date: January 4, 2018Applicant: SEDERMAInventors: Olivier Peschard, Anne Doucet, Richard Leroux, Philippe Mondon
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Publication number: 20170157014Abstract: The peptides have the general following formula: X-Pro*-Pro*-Xaa-Y in which: —Xaa is selected from Leucine (Leu, L), Arginine (Arg, R), Lysine (Lys, K), Alanine (Ala, A), Serine (Ser, S), and Aspartic acid (Asp, D); —At the N terminal end of the peptide, X is selected from H, —CO—R1 and —SO2—R1; —At the C terminal end of the peptide, Y is selected from OH, OR1, NH2, NHR1 and NR1R2; —R1 and R2 are, independently from each other, selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy and aryloxy group, that can be linear, branched, cyclic, poly-cyclic, non-saturated, hydroxylated, carbonylated, phosphorylated and/or sulfured, and which skeletum can comprise an heteroatom, in particular an O, S and/or N atom; —Pro* correspond to a Proline, an analogue or derivative thereof; —if X is H then Y is selected from OR1, NH2, NHR1 and NR1R2, and if Y is OH then X is —CO— or —SO2—R1; and the peptide hypoxanthine-Pro-Pro-Arg being excluded.Type: ApplicationFiled: May 21, 2015Publication date: June 8, 2017Applicant: SEDERMAInventors: OLIVIER PESCHARD, ANNE DOUCET, RICHARD LEROUX, PHILIPPE MONDON
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Patent number: 7501364Abstract: The present invention provides a non-woven felt material that includes a blend of cotton shoddy and synthetic fibers, and a method of making the same. The blend of cotton shoddy and synthetic fibers is carded and needled to form a batt. The batt is compacted and unified into its stable final shape by heating and soft-pressing, which causes at least a portion of the synthetic fibers to soften and/or melt and thereby bond the needled cotton shoddy and synthetic fibers together. The non-woven felt material according to the invention is strong, tear resistant, yet provides a non-slip, cushioned walking surface that readily absorbs and contains spilled oils, water and/or glycols.Type: GrantFiled: November 29, 2006Date of Patent: March 10, 2009Assignee: Bouckaert Industrial Textiles, Inc.Inventors: Thomas V. Bouckaert, Richard A. Leroux
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Publication number: 20080124533Abstract: The present invention provides a non-woven felt material that includes a blend of cotton shoddy and synthetic fibers, and a method of making the same. The blend of cotton shoddy and synthetic fibers is carded and needled to form a batt. The batt is compacted and unified into its stable final shape by heating and soft-pressing, which causes at least a portion of the synthetic fibers to soften and/or melt and thereby bond the needled cotton shoddy and synthetic fibers together. The non-woven felt material according to the invention is strong, tear resistant, yet provides a non-slip, cushioned walking surface that readily absorbs and contains spilled oils, water and/or glycols.Type: ApplicationFiled: November 29, 2006Publication date: May 29, 2008Applicant: Bouckaert Industrial Textiles, Inc.Inventors: Thomas V. Bouckaert, Richard A. Leroux