Patents by Inventor Richard Lewis Jarvest

Richard Lewis Jarvest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14 and 15 membered ring compounds
    Patent number: 7569550
    Abstract: The present invention relates to 14- or 15-membered macrolides substituted at the 4? position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: August 4, 2009
    Assignees: Glaxo Group Limited, Pliva-Istrazivacki Institut
    Inventors: Sulejman Alihodzic, Andrew Keith Forrest, Richard Lewis Jarvest, Gorjana Lazarevski, Drazen Pavlovic
  • Novel 14 and 15 Membered Ring Compounds
    Publication number: 20080221158
    Abstract: The present invention relates to 15-membered macrolides substituted at the 4? position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body.
    Type: Application
    Filed: May 11, 2004
    Publication date: September 11, 2008
    Inventors: Sulejman Alihodzic, Andrea Berdik, Richard Lewis Jarvest, Gorjana Lazarevski
  • Compounds
    Patent number: 7351696
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their preparation and their use in therapy or prophylaxis of systemic or topical microbial infections in a human or animal body.
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: April 1, 2008
    Assignee: Glaxo Group Limited
    Inventors: John Michael Berge, Catherine Simone Victoire Frydrych, Richard Lewis Jarvest
  • Pleuromutilin derivatives
    Patent number: 7160907
    Abstract: Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: January 9, 2007
    Assignee: SmithKline Beecham P.L.C.
    Inventors: John Stephen Elder, Andrew Keith Forrest, Richard Lewis Jarvest, Robert John Sheppard
  • Pleuromutilin derivatives
    Patent number: 6900345
    Abstract: Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy.
    Type: Grant
    Filed: October 8, 2001
    Date of Patent: May 31, 2005
    Assignee: SmithKline Beecham p.l.c.
    Inventors: John Stephen Elder, Andrew Keith Forrest, Richard Lewis Jarvest, Robert John Sheppard
  • Novel pleuromutilin derivatives
    Publication number: 20040024059
    Abstract: Pleuromutilin compounds of the formula (A) & (B) are of use in anti-bacterial therapy.
    Type: Application
    Filed: July 25, 2003
    Publication date: February 5, 2004
    Inventors: John Stephen Elder, Andrew Keith Forrest, Richard Lewis Jarvest, Robert John Sheppard
  • Antiviral guanine derivatives
    Patent number: 6579981
    Abstract: A compound of formula (I) or a salt or acyl derivative thereof, in which X represents chlorine, C1-6 alkoxy, phenoxy, phenyl C1-6 alkoxy, NH2, —OH or —SH, is useful in treating viral infections.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: June 17, 2003
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Richard Lewis Jarvest, Michael Raymond Harnden
  • Antiviral guanine derivatives
    Patent number: 6573378
    Abstract: A compound of formula (I) or a salt or acyl derivative thereof, in which X represents chlorine, C1-6 alkoxy, phenoxy, phenyl C1-6 alkoxy, NH2, —OH or —SH, is useful in treating viral infections.
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: June 3, 2003
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Richard Lewis Jarvest, Michael Raymond Harnden
  • Process for the preparation of purine derivatives
    Patent number: 6388074
    Abstract: The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to form a guanine) or hydrogen (to form a 2-aminopurine), respectively.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: May 14, 2002
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Graham Richard Geen, Richard Lewis Jarvest
  • Quinolones used as MRS inhibitors and bactericides
    Patent number: 6320051
    Abstract: Compounds of formula (I) are inhibitors of the bacterial enzyme S aureus methionyl tRNA synthetase and are of use in treating bacterial infections.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: November 20, 2001
    Assignee: SmithKline Beecham plc
    Inventors: John Michael Berge, Pamela Brown, John Stephen Elder, Andrew Keith Forrest, Dieter Wolfgang Hamprecht, Richard Lewis Jarvest, David Jonathan McNair, Robert John Sheppard
  • Process for the preparation of purine derivatives
    Publication number: 20010004668
    Abstract: The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to form a guanine) or hydrogen (to form a 2-aminopurine), respectively.
    Type: Application
    Filed: December 11, 2000
    Publication date: June 21, 2001
    Applicant: Beecham Group plc
    Inventors: Graham Richard Geen, Richard Lewis Jarvest
  • Process for the preparation of purine derivatives
    Patent number: 6187922
    Abstract: The present invention provides for the compound and synthesis of 9-(4-acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine, which compound is an intermediate involved in the synthesis of penciclovir and famciclovir.
    Type: Grant
    Filed: January 27, 1999
    Date of Patent: February 13, 2001
    Assignee: SmithKline Beecham plc
    Inventors: Graham Richard Geen, Richard Lewis Jarvest
  • 2-acetoxymethyl-4-halo-butyl-1-yl acetates
    Patent number: 5886215
    Abstract: The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to form a guanine) or hydrogen (to form a 2-aminopurine), respectively; and 2-acetoxymethyl-4-halo-butyl-1-yl acetates.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: March 23, 1999
    Assignee: SmithKline Beecham plc
    Inventors: Graham Richard Geen, Richard Lewis Jarvest
  • Process for the preparation of purine derivatives
    Patent number: 5684153
    Abstract: The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting the compound 2-amino-6-chloropurine (ACP) with 2-acetoxymethyl-4-(leaving group)-but-1-yl acetate, followed by displacement of the 6-chloro moiety with a hydroxy moiety (i.e. to form a guanine derivative) or with hydrogen (to form the 2-aminopurine derivative), respectively.
    Type: Grant
    Filed: June 10, 1994
    Date of Patent: November 4, 1997
    Assignee: Beecham Group plc
    Inventors: Graham Richard Geen, Richard Lewis Jarvest