Patents by Inventor Richard Lottenberg

Richard Lottenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial plasmin receptors as fibrinolytic agents
    Patent number: 6136323
    Abstract: The subject invention concerns novel methods and compositions for thrombolytic therapy. More specifically, a receptor with high affinity for plasmin has been characterized, purified, cloned, and expressed. This receptor can be used in combination therapies where it is administered prior to, concurrently with, or after a plasminogen activator. Also, this receptor can be bound to plasmin and administered to humans or animals in need of fibrinolytic activity. Additionally, the invention pertains to a novel immobilized form of plasmin which advantageously accumulates at the point where antifibrinolytic activity is needed.
    Type: Grant
    Filed: July 11, 1994
    Date of Patent: October 24, 2000
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michael D. P. Boyle, Richard Lottenberg, Christopher Broder, Gregory Von Mering
  • Bacterial plasmin receptors as fibrinolytic agents
    Patent number: 5328996
    Abstract: The subject invention concerns novel methods and compositions for thrombolytic therapy. More specifically, a receptor with high affinity for plasmin has been characterized, purified, cloned, and expressed. This receptor can be used in combination therapies where it is administered prior to, concurrently with, or after a plasminogen activator. Also, this receptor can be bound to plasmin and administered to humans or animals in need of fibrinolytic activity. Additionally, the invention pertains to a novel immobilized form of plasmin which advantageously accumulates at the point where antifibrinolytic activity is needed.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: July 12, 1994
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michael D. P. Boyle, Richard Lottenberg, Christopher Broder, Gregory Von Mering
  • Bacterial plasmin receptors as fibrinolytic agents
    Patent number: 5237050
    Abstract: The subject invention concerns novel methods and compositions for thrombolytic therapy. More specifically, a receptor with high affinity for plasmin has been characterized, purified, cloned, and expressed. This receptor can be used in combination therapies where it is administered prior to, concurrently with, or after a plasminogen activator. Also, this receptor can be bound to plasmin and administered to humans or animals in need of fibrinolytic activity. Additionally, the invention pertains to a novel immobilized form of plasmin which advantageously accumulates at the point where antifibrinolytic activity is needed.
    Type: Grant
    Filed: May 15, 1990
    Date of Patent: August 17, 1993
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michael D. P. Boyle, Richard Lottenberg, Christopher Broder, Gregory Von Mering