Patents by Inventor Richard M. Breyer

Richard M. Breyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for high yield production of eukaryotic proteins
    Publication number: 20030228569
    Abstract: The present invention provides an isolated nucleic acid comprising a first nucleotide sequence encoding an amino acid sequence comprising at least three positively charged amino acid residues, positioned upstream and in frame with a second nucleotide sequence encoding a protein. In addition, the present invention provides an isolated nucleic acid comprising a first nucleotide sequence encoding a DNA binding protein, positioned upstream and in frame with a second nucleotide sequence encoding a protein. An isolated nucleic acid is also provided, which comprises a first nucleotide sequence encoding a bacteriophage lambda repressor protein, positioned upstream and in frame with a second nucleotide sequence encoding a protein.
    Type: Application
    Filed: May 3, 2002
    Publication date: December 11, 2003
    Applicant: Vanderbilt University
    Inventors: Richard M. Breyer, Lijun Ma, Chris Kennedy
  • Methods and compositions for high yield production of eukaryotic proteins
    Patent number: 6383777
    Abstract: The present invention provides an isolated nucleic acid comprising a first nucleotide sequence encoding an amino acid sequence comprising at least three positively charged amino acid residues, positioned upstream and in frame with a second nucleotide sequence encoding a protein. In addition, the present invention provides an isolated nucleic acid comprising a first nucleotide sequence encoding a DNA binding protein, positioned upstream and in frame with a second nucleotide sequence encoding a protein. An isolated nucleic acid is also provided, which comprises a first nucleotide sequence encoding a bacteriophage lambda repressor protein, positioned upstream and in frame with a second nucleotide sequence encoding a protein.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: May 7, 2002
    Assignee: Va{umlaut over (n)}derbilt University
    Inventors: Richard M. Breyer, Lijun Ma, Chris Kennedy