Patents by Inventor Richard M. Denney

Richard M. Denney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid cell lines producing monoclonal antibodies directed against neurotransmitter degrading enzymes
    Patent number: 4571381
    Abstract: A continuous hybrid cell line which produces monoclonal antibody directed against the neurotransmitter degrading enzyme, monoamine oxidase B (MAO B), has been developed. The hybrid cell line was established by fusing MAO B primed, differentiated lymphoid cells with myeloma cells. Resulting fused cells were isolated, cloned and characterized as to antibody specificity against antigenic determinants of MAO B. Monoclonal antibody having specificity for MAO B and no cross reactivity with MAO A was selected and implemented in a radioimmunoassay technique for the selective measurement of MAO B concentration independent of its catalytic activity.
    Type: Grant
    Filed: September 29, 1982
    Date of Patent: February 18, 1986
    Assignee: The University of Texas System Board of Regents
    Inventors: Creed W. Abell, Richard M. Denney