Patents by Inventor Richard M. LoPachin

Richard M. LoPachin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIFUNCTIONAL CYTOPROTECTANT FOR TREATMENT OF PATHOGENIC PROCESSES MEDIATED BY OXIDATIVE STRESS AND TOXIC ELECTROPHILES
    Publication number: 20230133011
    Abstract: Methods, filters and compositions are disclosed for treating toxicity due to oxidative stress and toxic electrophiles.
    Type: Application
    Filed: August 2, 2022
    Publication date: May 4, 2023
    Applicant: MONTEFIORE MEDICAL CENTER
    Inventors: Richard M. LOPACHIN, Terrence GAVIN, Brian GEOHAGEN
  • Multifunctional cytoprotectant for treatment of pathogenic processes mediated by oxidative stress and toxic electrophiles
    Patent number: 11413255
    Abstract: Methods, filters and compositions are disclosed for treating toxicity due to oxidative stress and toxic electrophiles.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: August 16, 2022
    Assignee: Montefiore Medical Center
    Inventors: Richard M. LoPachin, Terrence Gavin, Brian Geohagen
  • Methods and compositions for preventing and treating electrophile-mediated toxicities
    Patent number: 10104882
    Abstract: Methods and compositions using 1,3-dicarbonyl compounds are disclosed for treating toxicity due to therapeutic agents and agents that causes oxidative cellular damage and for treating liver ischemia-reperfusion injury, as well as diseases and disorders that are improved through administration of N-acetylcysteine.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: October 23, 2018
    Assignee: Montefiore Medical Center
    Inventors: Richard M. LoPachin, Terrence Gavin
  • MULTIFUNCTIONAL CYTOPROTECTANT FOR TREATMENT OF PATHOGENIC PROCESSES MEDIATED BY OXIDATIVE STRESS AND TOXIC ELECTROPHILES
    Publication number: 20180169037
    Abstract: Methods, filters and compositions are disclosed for treating toxicity due to oxidative stress and toxic electrophiles.
    Type: Application
    Filed: June 27, 2016
    Publication date: June 21, 2018
    Applicant: Montefiore Medical Center
    Inventors: Richard M. LoPachin, Terrence Gavin
  • METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING ELCTROPHILE-MEDIATED TOXICITIES
    Publication number: 20160074339
    Abstract: Methods and compositions using 1,3-dicarbonyl compounds are disclosed for treating toxicity due to therapeutic agents and agents that causes oxidative cellular damage and for treating liver ischemia-reperfusion injury, as well as diseases and disorders that are improved through administration of N-acetylcysteine.
    Type: Application
    Filed: April 28, 2014
    Publication date: March 17, 2016
    Applicant: MONTEFIORE MEDICAL CENTER
    Inventors: Richard M. LoPachin, Terrence Gavin
  • Methods and compositions for treating conditions mediated by oxidative stress or electrophilic environmental toxins
    Patent number: 8835510
    Abstract: Methods and compositions are disclosed for treating a subject with a disease or tissue injury mediated by cellular oxidative stress or with an environmental toxicity due to an electrophilic toxicant or pollutant, and for providing a nutritional supplement to a subject and for providing a skin treatment for a subject, where the methods comprise administering to the subject a 1,3-dicarbonyl compound.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: September 16, 2014
    Assignee: Montefiore Medical Center
    Inventors: Richard M. LoPachin, Terrence Gavin
  • METHODS AND COMPOSITIONS FOR TREATING CONDITIONS MEDIATED BY OXIDATIVE STRESS OR ELECTROPHILIC ENVIRONMENTAL TOXINS
    Publication number: 20130116337
    Abstract: Methods and compositions are disclosed for treating a subject with a disease or tissue injury mediated by cellular oxidative stress or with an environmental toxicity due to an electrophilic toxicant or pollutant, and for providing a nutritional supplement to a subject and for providing a skin treatment for a subject, where the methods comprise administering to the subject a 1,3-dicarbonyl compound.
    Type: Application
    Filed: June 1, 2011
    Publication date: May 9, 2013
    Inventors: Richard M. LoPachin, Terrence Gavin