Abstract: In accordance with various embodiments of the disclosed subject matter, a system, device and platform for culturing and maintaining tissue representative cellular models combined with active fluidics mimicking body circulation. In combination, multiple chamber devices enable modeling of multi-organ communication, representative of in vivo conditions.

Abstract: In various embodiments, both very high speed and very high sensitivity hydrogen detection is achieved by controlling water vapor concentration over the catalyst used to convert hydrogen in sample gas (e.g., ambient air) to water vapor, to provide a substantially stable water vapor mixing level at a target mixing ratio. The naturally-occurring water vapor in the sample gas, without further steps, typically would vary over time within a wide range (e.g., due to changing atmospheric conditions). By controlling a level of water vapor over the catalyst to be substantially equal to a target mixing ratio that is not too low as to impair response time, and not too high as to impair sensitivity, both very high speed and very high sensitivity can be provided.

Abstract: In accordance with the present invention, a set of golf club heads is disclosed. The set includes golf club heads with peripheral weights. The dimensions and configuration of at least the peripheral weights are changed from club-to-club along the set so that the center of gravity rises from the long irons to the short irons. By raising the center of gravity from the long irons to the short irons, a golfer will see a peak trajectory height along a line for each club head that is substantially more consistent along that line throughout the set than prior art clubs provide.

Abstract: A wedge type golf club head is disclosed herein where the wedge type golf club head has enhanced performance characteristics such as improved backspin, ball speed, and launch angle. More specifically, the present invention relates to a wedge type golf club head having an adjustable center of gravity, where the center of gravity may be adjusted based on different backing profiles that comprises at least one hollow chamber. The wedge type golf club head disclosed above may also have a thickened topline, wherein the thickness of the topline progressively changes as a function of the loft angle of the wedge type golf club head.

Abstract: In accordance with the present invention, a set of golf club heads is disclosed. The set includes golf club heads with peripheral weights. The dimensions and configuration of at least the peripheral weights are changed from club-to-club along the set so that the center of gravity rises from the long irons to the short irons. By raising the center of gravity from the long irons to the short irons, a golfer will see a peak trajectory height along a line for each club head that is substantially more consistent along that line throughout the set than prior art clubs provide.

Abstract: In accordance with the present invention, a set of golf club heads is disclosed. The set includes golf club heads with peripheral weights. The dimensions and configuration of at least the peripheral weights are changed from club-to-club along the set so that the center of gravity rises from the long irons to the short irons. By raising the center of gravity from the long irons to the short irons, a golfer will see a peak trajectory height along a line for each club head that is substantially more consistent along that line throughout the set than prior art clubs provide.

Abstract: A wedge type golf club head is disclosed herein where the wedge type golf club head has enhanced performance characteristics such as improved backspin, ball speed, and launch angle. More specifically, the present invention relates to a wedge type golf club head having an adjustable center of gravity, where the center of gravity may be adjusted based on different backing profiles that comprises at least one hollow chamber. The wedge type golf club head disclosed above may also have a thickened topline, wherein the thickness of the topline progressively changes as a function of the loft angle of the wedge type golf club head.

Abstract: A wedge type golf club head is disclosed herein where the wedge type golf club head has enhanced performance characteristics such as improved backspin, ball speed, and launch angle. More specifically, the present invention relates to a wedge type golf club head having an adjustable center of gravity, where the center of gravity may be adjusted based on different backing profiles that comprises at least one hollow chamber. The wedge type golf club head disclosed above may also have a thickened topline, wherein the thickness of the topline progressively changes as a function of the loft angle of the wedge type golf club head.

Abstract: A wedge type golf club head is disclosed herein where the wedge type golf club head has enhanced performance characteristics such as improved backspin, ball speed, and launch angle. More specifically, the present invention relates to a wedge type golf club head having an adjustable center of gravity, where the center of gravity may be adjusted based on different backing profiles that comprises at least one hollow chamber. The wedge type golf club head disclosed above may also have a thickened topline, wherein the thickness of the topline progressively changes as a function of the loft angle of the wedge type golf club head.

Abstract: The invention relates to fluorescence polarization (FP) methods for detecting and evaluating ligand binding to steroid receptors which are associated with heat shock proteins (hsps). The invention also relates to novel labeled molecules, in particular, fluorescence probes, which are useful in the methods of the invention.

Abstract: An iron type golf club head including a bottom sole having a first level support surface at a first angle relative to the ball striking face, a second level support surface at a second angle relative to the ball striking face, and a third level support surface offset laterally from the first and second levels at a third angle relative to the ball striking face.

Abstract: Selectin binding and inflammation is modulated by a method which utilizes inositol polyaninon.

Abstract: Selectin receptor binding is modulated by a method which utilizes heparin-like oligosaccharides.

Abstract: Indirect method of detecting elastase-modified or cleaved, antithrombin (ATx) in the presence of intact antithrombin (AT-III). The inventive method includes a modified ELISA using a detergent to alter the intact AT-III. Cleaved AT-III is generated in human plasma, then an ELISA is performed in the presence of a detergent.

Abstract: A splint for a hind leg of an animal such as a dog or cat. The splint is shaped to conform to the normal shape of the hind leg of an animal and serves to sustain the weight of the animal while walking without imposing stress upon the leg in the region of the break.

Abstract: Adjustable guide vanes (70) are circumferentially disposed about a rotor (40) at each stage of a multi-stage turbine (10) and are slidably connected to pairs of rotatable vane rings (61, 62) at each stage, the rings and guide vanes defining nozzles (82) leading from a scroll case (30) to the rotor at each stage, the nozzles having contoured surfaces (80) for minimizing hydraulic losses. Yoke mechanisms (104, 106) and interconnecting members (98, 100) link each pair of rotatable vane rings to a single actuator shaft (90) for synchronous adjustment of the positions of the guide vanes to vary the cross-sectional areas of the nozzles thereby permitting operation at optimum efficiency in response to changing flow rates.

Abstract: A double-case, multi-stage, centrifugal pump having a plurality of impellers mounted on a common shaft at axially spaced pump stages. The first pump stage is housed within a unitary forward case section of a three-section inner case assembly. Subsequent stages are housed within two rearward case sections disposed in axial joint-forming relationship with each other and radial joint-forming relationship with the forward case section. The inner case assembly is supported within an outer case assembly which provides a suction chamber surrounding the forward case section and a discharge chamber surrounding the rearward case sections, the inner and outer case assemblies being constructed in such manner that the pressure in the discharge chamber sealably forces the inner case sections together during operation of the pump.