Patents by Inventor Richard M. Woodward

Richard M. Woodward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Compositions of a Neuroactive Steroid and Methods of Use Thereof
    Publication number: 20120276196
    Abstract: The present invention relates to pharmaceutical compositions of the neuroactive steroid 3?-hydroxy-3?-methoxymethyl-21-(1?-imidazolyl)-5?-pregnan-20-one or a pharmaceutically-acceptable salt or solvate thereof, with properties desirable for use in treating mood disorders and the like. The pharmaceutical compositions provide sustained therapeutic plasma levels of 3?-hydroxy-3?-methoxymethyl-21-(1?-imidazolyl)-5?-pregnan-20-one. The present invention also relates to methods of treating these disorders by administering the pharmaceutical compositions.
    Type: Application
    Filed: May 4, 2012
    Publication date: November 1, 2012
    Applicant: Euro-Celtique S.A.
    Inventor: Richard M. WOODWARD
  • USE OF AN OPIOID RECEPTOR ANTAGONIST FOR THE TREATMENT OR PREVENTION OF GASTROINTESTINAL TRACT DISORDERS
    Publication number: 20110071163
    Abstract: The disclosure relates to a method of treating or preventing a condition in a subject associated with the activation of an opioid receptor in the periphery by administering an effective amount of 5-(2-methoxy-4-{[2-(tetrahydro-pyran-4-yl)-ethylamino]-methyl}-phenoxy)-pyrazine-2-carboxamide (Compound I). In particular, the disclosure relates to a method of treating or preventing opioid-induced constipation or opioid-induced bowel dysfunction in a human without reducing centrally-mediated opioid analgesia or producing central opioid withdrawal symptoms by administering an effective amount of Compound I. The disclosure further relates to the use of Compound I for the preparation of a medicament for the treatment or prevention of a condition in a subject associated with the activation of an opioid receptor in the periphery.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 24, 2011
    Applicant: ADOLOR CORPORATION
    Inventor: Richard M. WOODWARD
  • Pharmaceutical compositions of a neuroactive steriod and methods of use thereof
    Publication number: 20090131383
    Abstract: The present invention relates to pharmaceutical compositions of the neuroactive steroid 3?-hydroxy-3?-methoxymethyl-21-(1?-imidazolyl)-5?-pregnan-20-one or a pharmaceutically-acceptable salt or solvate thereof, with properties desirable for use in treating mood disorders and the like. The pharmaceutical compositions provide sustained therapeutic plasma levels of 3?-hydroxy-3?-methoxymethyl-21-(1?-imidazolyl)-5?-pregnan-20-one. The present invention also relates to methods of treating these disorders by administering the pharmaceutical compositions.
    Type: Application
    Filed: June 9, 2006
    Publication date: May 21, 2009
    Inventor: Richard M. Woodward
  • Methods for use of GABA.sub.a receptor GABAergic compounds
    Patent number: 5637617
    Abstract: A method is disclosed for potentiating mammalian GABA.sub.A receptor responses to GABA. The receptor responses are potentiated according to the invention by contacting GABA.sub.A receptors with GABA and an effective amount of non-steroidal anti-inflammatory agents, in particular, fenamates and structurally related compounds.
    Type: Grant
    Filed: April 1, 1994
    Date of Patent: June 10, 1997
    Assignee: The Regents of the University of California
    Inventors: Richard M. Woodward, Ricardo Miledi
  • Selective antagonists for GABA.sub.rho receptor
    Patent number: 5627169
    Abstract: Novel phosphinic and phosphonic acid derivatives of pyridine, pyrrole and azepine with utility as antagonists of the GABA.sub.rho receptor are disclosed. These compounds have utility as modulators of the excitability of the central nervous system as mediated by their ability to specifically act on closed-channel binding sites of GABA.sub.rho receptors.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: May 6, 1997
    Assignee: The Regents of The University of California
    Inventors: Ricardo Miledi, Larry E. Overman, Yoshinori Murata, Richard M. Woodward