Abstract: A port and closure device for a vessel that is configured for use with a glove bag. The port comprising includes a first annular flange with an opening, a second annular flange disposed a predetermined distance from the first flange and also having an opening, and a seal ring disposed adjacent the first annular flange and having an additional opening. At least a portion of the openings are aligned so that a path is provided through the flanges and the seal ring. A slideable door is included in the port between the seal ring and the second annular flange. The slideable door has a first position that obstructs the path and a second position that is outside of the path. Springs are disposed between the first flange and the seal ring that urge the seal ring toward the slideable door. To reduce contamination sites, the springs may be sealed within an annular interface between the first annular flange and the seal ring.

Abstract: A port and closure device for a vessel that is configured for use with a glove bag. The port comprising includes a first annular flange with an opening, a second annular flange disposed a predetermined distance from the first flange and also having an opening, and a seal ring disposed adjacent the first annular flange and having an additional opening. At least a portion of the openings are aligned so that a path is provided through the flanges and the seal ring. A slideable door is included in the port between the seal ring and the second annular flange. The slideable door has a first position that obstructs the path and a second position that is outside of the path. Springs are disposed between the first flange and the seal ring that urge the seal ring toward the slideable door. To reduce contamination sites, the springs may be sealed within an annular interface between the first annular flange and the seal ring.

Abstract: An illuminating and viewing unit for illuminating the interior of a vessel with source radiation and observing the vessel interior comprises a housing including a front wall facing the vessel interior. The front wall is of a material that does not transmit the source radiation, and includes one or more illumination ports individually fused into the front wall that transmit the source radiation to the vessel interior. A detection port is also individually fused into the front wall for transmitting detectable radiation along a detection path from the vessel interior to a radiation detector mounted in the housing. The optical isolation of the illumination and detection ports in the front wall prevents unwanted internal reflection of source radiation into the detection path, and allows for independent selection of port materials and configurations, while maintaining a hermetic seal between the housing and the internal contents of the vessel.