Patents by Inventor Richard Masaru Kawamoto

Richard Masaru Kawamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTAL OF HYPOXIA INDUCIBLE FACTOR 1 ALPHA PROLYL HYDROXYLASE
    Publication number: 20120282627
    Abstract: The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.
    Type: Application
    Filed: September 12, 2011
    Publication date: November 8, 2012
    Inventors: Artem Gennady Evdokimov, Richard Masaru Kawamoto, Angelique Sun Boyer, Marlene Jan Mekel, Matthew Eugene Pokross, Richard Lee Walter, JR.
  • Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
    Patent number: 8050873
    Abstract: The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: November 1, 2011
    Assignee: Warner Chilcott Company
    Inventors: Artem Gennady Evdokimov, Richard Masaru Kawamoto, Angelique Sun Boyer, Marlene Jan Mekel, Matthew Eugene Pokross, Richard Lee Walter, Jr.
  • PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE
    Publication number: 20100331303
    Abstract: The present disclosure relates to HIF-1? prolyl hydroxylase inhibitors, compositions which comprise the HIF-1? prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 30, 2010
    Inventors: Richard Masaru Kawamoto, Shengde Wu, Namal C. Warshakoon, Artem G. Evdokimov, Kenneth D. Greis, Angelique Sun Boyer
  • PROLYL HYDROXYLASE INHIBITORS AND METHODS OF USE
    Publication number: 20100331374
    Abstract: The present disclosure relates to HIF-1? prolyl hydroxylase inhibitors, compositions which comprise the HIF-1? prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 30, 2010
    Inventors: Shengde Wu, Namal C. Warshakoon, Artem G. Evdokimov, Kenneth D. Greis, Angelique Sun Boyer, Richard Masaru Kawamoto
  • Prolyl hydroxylase inhibitors and methods of use
    Patent number: 7811595
    Abstract: The present disclosure relates to HIF-1? prolyl hydroxylase inhibitors, compositions which comprise the HIF-1? prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: October 12, 2010
    Assignee: Warner Chilcott Company, LLC
    Inventors: Richard Masaru Kawamoto, Shengde Wu, Namal C. Warshakoon, Artem G. Evdokimov, Kenneth D. Greis, Angelique Sun Boyer
  • THREE DIMENSIONAL COORDINATES OF HYPOXIA INDUCIBLE FACTOR 1 ALPHA (HIF-1 ALPHA) PROLYL HYDROXYLASE (EGLN1) AND USES THEREOF
    Publication number: 20090240475
    Abstract: The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.
    Type: Application
    Filed: May 28, 2009
    Publication date: September 24, 2009
    Inventors: ARTEM GENNADY EVDOKIMOV, RICHARD MASARU KAWAMOTO, SUN BOYER, MERLENE JAN MEKEL, METTHEW EUGENE POKROSS, RICHARD LEE WALTER, JR.
  • Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
    Patent number: 7588924
    Abstract: The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.
    Type: Grant
    Filed: March 5, 2007
    Date of Patent: September 15, 2009
    Assignee: Procter & Gamble Company
    Inventors: Artem Gennady Evdokimov, Richard Masaru Kawamoto, Angelique Sun Boyer, Marlene Jan Mekel, Matthew Eugene Pokross, Richard Lee Walter, Jr.
  • Three dimensional coordinates of hypoxia inducible factor 1 alpha (HIF-1 alpha)-prolyl hydroxylase (EGLN1) and uses thereof
    Publication number: 20080124740
    Abstract: The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.
    Type: Application
    Filed: March 5, 2007
    Publication date: May 29, 2008
    Inventors: Artem Gennady Evdokimov, Richard Masaru Kawamoto, Angelique Sun Boyer, Marlene Jan Mekel, Matthew Eugene Pokross, Richard Lee Walter
  • Medicinal uses of dihydropyrazoles
    Patent number: 6878729
    Abstract: Compounds having a structure according to Formula (I): are effective in a method of increasing erythropoietin and vascularization of tissue in a subject in need thereof.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: April 12, 2005
    Assignee: The Procter & Gamble Company
    Inventors: Ji-In Kim Almstead, Nicholas John Izzo, David Robert Jones, Richard Masaru Kawamoto
  • Medicinal uses of hydrazones
    Publication number: 20040053977
    Abstract: Compounds having a structure according to Formula (I): 1
    Type: Application
    Filed: September 12, 2003
    Publication date: March 18, 2004
    Inventors: Ji-In Kim Almstead, Nicholas John Izzo, David Robert Jones, Richard Masaru Kawamoto
  • Medicinal uses of hydrazones
    Patent number: 6660737
    Abstract: Compounds having a structure according to Formula (I): are effective in a method of increasing erythropoietin and vascularization of tissue in a subject in need thereof.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: December 9, 2003
    Assignee: The Procter & Gamble Company
    Inventors: Ji-In Kim Almstead, Nicholas John Izzo, David Robert Jones, Richard Masaru Kawamoto
  • Medicinal uses of hydrazones
    Publication number: 20030092716
    Abstract: Compounds having a structure according to Formula (I): 1
    Type: Application
    Filed: April 29, 2002
    Publication date: May 15, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Ji-In Kim Almstead, Nicholas John Izzo, David Robert Jones, Richard Masaru Kawamoto
  • Medicinal uses of dihydropyrazoles
    Publication number: 20030083351
    Abstract: Compounds having a structure according to Formula (I): 1
    Type: Application
    Filed: April 29, 2002
    Publication date: May 1, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Ji-In Kim Almstead, Nicholas John Izzo, David Robert Jones, Richard Masaru Kawamoto