Patents by Inventor Richard Masten Fine

Richard Masten Fine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SCREENING METHODS USING CANINE T2R RECEPTORS AND PET FOOD PRODUCTS AND COMPOSITIONS IDENTIFIED USING THE SAME
    Publication number: 20220120734
    Abstract: The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of a bitter taste receptor.
    Type: Application
    Filed: January 5, 2022
    Publication date: April 21, 2022
    Applicant: MARS, INCORPORATED
    Inventors: Matthew Ronald Gibbs, Neil George Desforges, Andrew John Taylor, Scott Joseph McGrane, Boris Klebansky, Richard Masten Fine
  • SCREENING METHODS USING GPRC6A TASTE RECEPTORS AND PET FOOD PRODUCTS AND COMPOSITIONS PREPARED USING THE SAME
    Publication number: 20220087288
    Abstract: The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of a taste receptor.
    Type: Application
    Filed: June 13, 2019
    Publication date: March 24, 2022
    Applicant: MARS INCORPORATED
    Inventors: Scott Joseph McGrane, Matthew Ronald Gibbs, Boris Klebansky, Richard Masten Fine
  • Methods for identifying modulators of GPR92
    Patent number: 11237177
    Abstract: The present disclosure provides methods for identifying compounds that modulate the activity and/or expression of GPR92, wherein said compounds can be incorporated into flavor compositions that can be used to modify the taste and/or palatability of pet food products. In certain non-limiting embodiments, the present disclosure provides a method for identifying a composition that modulates the activity of a GPR92 receptor comprising (a) contacting a test agent with a GPR92 receptor, (b) determining the activity of the GPR92 receptor, and (c) selecting as the composition, a test agent that increases the activity of the GPR92 receptor.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: February 1, 2022
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • Methods for modulating taste receptors
    Patent number: 11185100
    Abstract: Amino acids present in domains of an umami taste receptor are described herein, wherein the amino acids interact with at least one nucleotide derivative and/or at least one transmembrane compound that potentiates, modulates, increases, and/or enhances the activity of the umami receptor. Such compounds can be used in flavor compositions to enhance the umami taste and/or palatability of food products.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: November 30, 2021
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Richard Masten Fine, Boris Klebansky, Matthew Ronald Gibbs
  • COMPOUNDS THAT MODULATE FATTY ACID RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME
    Publication number: 20200397030
    Abstract: A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR120 fatty acid receptor that can be used to enhance the fatty acid taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.
    Type: Application
    Filed: September 8, 2020
    Publication date: December 24, 2020
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Matthew Ronald Gibbs, Richard Masten Fine, Jerry Wallace Skiles
  • Compounds that modulate fatty acid receptor activity and pet food products containing the same
    Patent number: 10827772
    Abstract: A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a GPR120 fatty acid receptor that can be used to enhance the fatty acid taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: November 10, 2020
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Matthew Ronald Gibbs, Richard Masten Fine, Jerry Wallace Skiles
  • SCREENING METHODS USING CANINE T2R RECEPTORS AND PET FOOD PRODUCTS AND COMPOSITIONS IDENTIFIED USING THE SAME
    Publication number: 20200292527
    Abstract: The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of a bitter taste receptor.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 17, 2020
    Applicant: MARS, INCORPORATED
    Inventors: Matthew Ronald Gibbs, Neil George Desforges, Andrew John Taylor, Scott Joseph McGrane, Boris Klebansky, Richard Masten Fine
  • Methods for identifying modulators of calcium-sensing receptors
    Patent number: 10775375
    Abstract: Methods for identifying compounds that modulate the activity and/or expression of a calcium-sensing receptor, wherein said compounds can be incorporated into flavor compositions that can be used to modify the kokumi taste and/or palatability of pet food products.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: September 15, 2020
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Richard Masten Fine, Boris Klebansky, Matthew Ronald Gibbs
  • Methods for increasing palatability of pet foodstuff
    Patent number: 10768184
    Abstract: The present invention relates to a method of identifying a compound that binds to or modulates the activity of one or more polypeptides encoding one or more receptors that are involved in the detection and perception of fatty acids.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: September 8, 2020
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • METHODS FOR INCREASING PALATABILITY OF PET FOODSTUFF
    Publication number: 20190361039
    Abstract: The present invention relates to a method of identifying a compound that binds to or modulates the activity of one or more polypeptides encoding one or more receptors that are involved in the detection and perception of fatty acids.
    Type: Application
    Filed: August 8, 2019
    Publication date: November 28, 2019
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • Methods for increasing palatability of pet foodstuff
    Patent number: 10473673
    Abstract: The present invention relates to a method of identifying a compound that binds to or modulates the activity of one or more polypeptides encoding one or more receptors that are involved in the detection and perception of fatty acids.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: November 12, 2019
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • METHODS FOR IDENTIFYING MODULATORS OF CALCIUM-SENSING RECEPTORS
    Publication number: 20190324031
    Abstract: Methods for identifying compounds that modulate the activity and/or expression of a calcium-sensing receptor, wherein said compounds can be incorporated into flavor compositions that can be used to modify the kokumi taste and/or palatability of pet food products.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 24, 2019
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Richard Masten Fine, Boris Klebansky, Matthew Ronald Gibbs
  • COMPOUNDS THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME
    Publication number: 20190274334
    Abstract: A flavor composition comprising at least one compound that modulates, increases and/or enhances the activity of a calcium-sensing receptor that can be used to enhance the kokumi taste and/or palatability of pet food products is described herein. Also disclosed herein are methods for identifying said compounds.
    Type: Application
    Filed: April 14, 2017
    Publication date: September 12, 2019
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky, Jerry Wallace Skiles
  • Methods for identifying modulators of calcium-sensing receptors
    Patent number: 10393740
    Abstract: Methods for identifying compounds that modulate the activity and/or expression of a calcium-sensing receptor, wherein said compounds can be incorporated into flavor compositions that can be used to modify the kokumi taste and/or palatability of pet food products.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: August 27, 2019
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Richard Masten Fine, Boris Klebansky, Matthew Ronald Gibbs
  • METHODS FOR INCREASING PALATABILITY OF PET FOODSTUFF
    Publication number: 20190187158
    Abstract: The present invention relates to a method of identifying a compound that binds to or modulates the activity of one or more polypeptides encoding one or more receptors that are involved in the detection and perception of fatty acids.
    Type: Application
    Filed: January 11, 2019
    Publication date: June 20, 2019
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • METHODS FOR IDENTIFYING MODULATORS OF GPR92
    Publication number: 20190170772
    Abstract: The present disclosure provides methods for identifying compounds that modulate the activity and/or expression of GPR92, wherein said compounds can be incorporated into flavor compositions that can be used to modify the taste and/or palatability of pet food products. In certain non-limiting embodiments, the present disclosure provides a method for identifying a composition that modulates the activity of a GPR92 receptor comprising (a) contacting a test agent with a GPR92 receptor, (b) determining the activity of the GPR92 receptor, and (c) selecting as the composition, a test agent that increases the activity of the GPR92 receptor.
    Type: Application
    Filed: April 14, 2017
    Publication date: June 6, 2019
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • Methods for increasing palatability of pet foodstuff
    Patent number: 10222387
    Abstract: The present invention relates to a method of identifying a compound that binds to or modulates the activity of one or more polypeptides encoding one or more receptors that are involved in the detection and perception of fatty acids.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: March 5, 2019
    Assignee: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Matthew Ronald Gibbs, Richard Masten Fine, Boris Klebansky
  • FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME
    Publication number: 20190021380
    Abstract: A flavor composition comprising at least one transmembrane compound and/or at least one nucleotide derivative that modulates, increases and/or enhances the activity of an umami receptor is provided that can be used to enhance the umami taste and/or palatability of food products. In certain, non-limiting embodiments, the flavor composition comprises at least one nucleotide derivative and/or at least one transmembrane compound, optionally at least one nucleotide, optionally at least one first amino acid, optionally at least one second amino acid.
    Type: Application
    Filed: December 10, 2015
    Publication date: January 24, 2019
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Richard Masten Fine, Jerry Wallace Skiles
  • SCREENING METHODS USING CANINE T2R RECEPTORS AND PET FOOD PRODUCTS AND COMPOSITIONS IDENTIFIED USING THE SAME
    Publication number: 20180372721
    Abstract: The presently disclosed subject matter relates to methods of screening raw materials and pet food products to manufacture a palatable pet food product. The presently disclosed subject matter also relates to methods for identifying compounds that modulate the activity and/or expression of a bitter taste receptor.
    Type: Application
    Filed: July 28, 2016
    Publication date: December 27, 2018
    Applicant: MARS, INCORPORATED
    Inventors: Matthew Ronald Gibbs, Neil George Desforges, Andrew John Taylor, Scott Joseph McGrane, Boris Klebansky, Richard Masten Fine
  • METHODS FOR MODULATING TASTE RECEPTORS
    Publication number: 20180255813
    Abstract: Amino acids present in domains of an umami taste receptor are described herein, wherein the amino acids interact with at least one nucleotide derivative and/or at least one transmembrane compound that potentiates, modulates, increases, and/or enhances the activity of the umami receptor. Such compounds can be used in flavor compositions to enhance the umami taste and/or palatability of food products.
    Type: Application
    Filed: December 10, 2015
    Publication date: September 13, 2018
    Applicant: MARS, INCORPORATED
    Inventors: Scott Joseph McGrane, Andrew John Taylor, Richard Masten Fine, Boris Klebansky, Matthew Ronald Gibbs