Patents by Inventor Richard Mayne

Richard Mayne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid and protein sequences of asporins
    Publication number: 20090048163
    Abstract: Mouse asporin protein and nucleic acid sequences are disclosed. The protein contains a unique aspartic acid region near the N-terminus. The central domain contains ten leucine rich repeats. Sequences consistent with other class I small leucine rich repeat proteoglycans (SLRP) are also observed. Methods of use for the protein include regulating the complement system, inhibiting fibrosis formation, regulating the growth of endothelial cells and angiogenesis, regulating or inhibiting the growth of cancer cells, and regulating the functions of neuromuscular junctions.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 19, 2009
    Inventors: Stephen P. Henry, A.O. Magnus Hook, Richard Mayne
  • Nucleotide and amino acid sequences of asporins
    Patent number: 7304137
    Abstract: Mouse asporin protein and nucleic acid sequences are disclosed. The protein contains a unique aspartic acid region near the N-terminus. The central domain contains ten leucine rich repeats. Sequences consistent with other class I small leucine rich repeat proteoglycans (SLRP) are also observed. Methods of use for the protein include regulating the complement system, inhibiting fibrosis formation, regulating the growth of endothelial cells and angiogenesis, regulating or inhibiting the growth of cancer cells, and regulating the functions of neuromuscular junctions.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: December 4, 2007
    Assignee: The Texas A & M University System
    Inventors: Stephen P. Henry, A. O. Magnus Hook, Richard Mayne
  • Nucleotide and amino acid sequences of asporins
    Publication number: 20030148351
    Abstract: Mouse asporin protein and nucleic acid sequences are disclosed. The protein contains a unique aspartic acid region near the N-terminus. The central domain contains ten leucine rich repeats. Sequences consistent with other class I small leucine rich repeat proteoglycans (SLRP) are also observed. Methods of use for the protein include regulating the complement system, inhibiting fibrosis formation, regulating the growth of endothelial cells and angiogenesis, regulating or inhibiting the growth of cancer cells, and regulating the functions of neuromuscular junctions.
    Type: Application
    Filed: December 13, 2002
    Publication date: August 7, 2003
    Inventors: Stephen P. Henry, A.O. Magnus Hook, Richard Mayne
  • Human vitreous and pharmaceutical compositions
    Publication number: 20020160937
    Abstract: In the vitreous, collagen fibrils and hyaluronan molecules form independent networks that interact to maintain the transparency of the vitreous gel. The discovery of the full length cDNA sequence of human vitrin makes it possible to produce the protein and its separate domains by known biotechnological means. It was found that vitrin is released from the collagen fibrils at high salt concentrations. The protein and expressed domains of the invention may be used to facilitate healing of weakened or injured connective tissue.
    Type: Application
    Filed: March 9, 2001
    Publication date: October 31, 2002
    Inventors: Richard Mayne, Zhao-Xia Ren, Jiangang Liu
  • Type IX collagen and fragments thereof
    Patent number: 6127523
    Abstract: The present invention relates to novel collagens and polynucleotide sequences encoding these novel proteins. The present invention further relates to specific collagens and derivatives, specifically .alpha.3(IX) collagen and recombinant trimeric type IX collagen protein.
    Type: Grant
    Filed: May 6, 1998
    Date of Patent: October 3, 2000
    Assignee: UAB Research Foundation
    Inventors: Randolph G. Brewton, Richard Mayne
  • Nucleic acid encoding a human .alpha.3(IX) collagen protein and method of producing the protein recombinantly
    Patent number: 5773248
    Abstract: The present invention relates to novel collagens and polynucleotide sequences encoding these novel proteins. The present invention further relates to specific collagens and derivatives, specifically .alpha.3(IX) collagen and recombinant trimeric type IX collagen protein.
    Type: Grant
    Filed: November 13, 1995
    Date of Patent: June 30, 1998
    Assignee: UAB Research Foundation
    Inventors: Randolph G. Brewton, Richard Mayne