Abstract: A method of screening for amyloid-binding compounds, amyloid-binding compounds, and a method of detecting amyloid-? (Abeta) plaques in a subject are disclosed. The method of screening for amyloid-binding compounds includes combining amyloid, a dye, and at least one test compound to form a sample solution; equilibrating the sample solution; measuring a fluorescence signal of the sample solution; and comparing the measured fluorescence signal of the sample to a control; wherein attenuation of the fluorescence signal, as compared to the control, indicates that one or more of the test compounds bind amyloid. The amyloid-binding compound includes a compound detected by the screening method. The method of detecting amyloid-? (Abeta) plaques in a subject includes administering one or more of the amyloid-binding compounds to the subject, and detecting the compound within the subject.

Abstract: A tool for field notching metal roof panels to allow the panels to properly nest within an end lap condition, the notching tool operable between an open and closed position. The notching tool is comprised of two mechanism assemblies, each assembly comprised of two handles with the proximal end of each handle connected to either a first jaw body or a second jaw body and the distal end of each handle connected to a handle separation member that spans the distance to the opposing mechanism assembly. At the distal end of each of the jaw bodies a pair of dies, male and female, that span the distance between the first and second mechanism assemblies. The male and female dies are used for severing excess material from the roof panel edges.

Abstract: A door module for a vehicle lavatory that includes a bi-fold door having a first panel and a second panel each having an inner surface and an outer surface. The first and second panels are pivotably connected together by a living hinge. The living hinge includes a hinge member that extends between first and second securing members, wherein the first securing member extends along and is attached to an inner edge of the first panel and the second securing member extends along and is attached to an inner edge of the second panel.

Abstract: A tool for field notching metal roof panels to allow the panels to properly nest within an end lap condition, the notching tool operable between an open and closed position. The notching tool is comprised of two mechanism assemblies, each assembly comprised of two handles with the proximal end of each handle connected to either a first jaw body or a second jaw body and the distal end of each handle connected to a handle separation member that spans the distance to the opposing mechanism assembly. At the distal end of each of the jaw bodies a pair of dies, male and female, that span the distance between the first and second mechanism assemblies. The male and female dies are used for severing excess material from the roof panel edges.

Abstract: A fastener system that includes a female fastener assembly with a housing having a channel defined therein and a switch member movable within the channel between removing and fastening positions. The switch member includes a receiver portion having a post opening defined therein and a switch portion. The housing includes a lower opening. The post opening includes a removing portion that is aligned with the lower opening when the switch member is in the removing position and a fastening portion that is aligned with the post opening when the switch member is in the fastening position. The system also includes a male fastener assembly having a post with a slot therein. The post is received through the lower opening in the housing and the post opening so that the slot is aligned with the channel. The slot receives a portion of the receiver portion when the switch member is in the fastening position.

Abstract: A fastener system that includes a female fastener assembly with a housing having a channel defined therein and a switch member movable within the channel between removing and fastening positions. The switch member includes a receiver portion having a post opening defined therein and a switch portion. The housing includes a lower opening. The post opening includes a removing portion that is aligned with the lower opening when the switch member is in the removing position and a fastening portion that is aligned with the post opening when the switch member is in the fastening position. The system also includes a male fastener assembly having a post with a slot therein. The post is received through the lower opening in the housing and the post opening so that the slot is aligned with the channel. The slot receives a portion of the receiver portion when the switch member is in the fastening position.

Abstract: A fastener system that includes a female fastener assembly with a housing having a channel defined therein and a switch member movable within the channel between removing and fastening positions. The switch member includes a receiver portion having a post opening defined therein and a switch portion. The housing includes a lower opening. The post opening includes a removing portion that is aligned with the lower opening when the switch member is in the removing position and a fastening portion that is aligned with the post opening when the switch member is in the fastening position. The system also includes a male fastener assembly having a post with a slot therein. The post is received through the lower opening in the housing and the post opening so that the slot is aligned with the channel. The slot receives a portion of the receiver portion when the switch member is in the fastening position.

Abstract: A door module for a vehicle lavatory that includes a bi-fold door having a first panel and a second panel each having an inner surface and an outer surface. The first and second panels are pivotably connected together by a living hinge. The living hinge includes a hinge member that extends between first and second securing members, wherein the first securing member extends along and is attached to an inner edge of the first panel and the second securing member extends along and is attached to an inner edge of the second panel.

Abstract: A door module for a vehicle lavatory that includes a bi-fold door having a first panel and a second panel each having an inner surface and an outer surface. The first and second panels are pivotably connected together by a living hinge. The living hinge includes a hinge member that extends between first and second securing members, wherein the first securing member extends along and is attached to an inner edge of the first panel and the second securing member extends along and is attached to an inner edge of the second panel.

Abstract: A door module for a vehicle lavatory that includes a bi-fold door having a first panel and a second panel each having an inner surface and an outer surface. The first and second panels are pivotably connected together by a living hinge. The living hinge includes a hinge member that extends between first and second securing members, wherein the first securing member extends along and is attached to an inner edge of the first panel and the second securing member extends along and is attached to an inner edge of the second panel.

Abstract: A support structure for supporting loads on a sloping metal panel roof includes first and second side rails, an upper diverter, and a lower closure. An upstanding web of the upper diverter extends upwardly from the panel flat. An elongate lower flange extends from the upstanding web and is disposed against the metal roof panel. Opposing rib mating webs are on opposing sides of the lower flange. On a first side of the lower flange, a diversion leg of the lower flange is between the upstanding web and one of the rib mating webs. On the second side of the lower flange, the second rib mating web meets the upstanding web. The lower flange extends from the upstanding web to a distal end thereof up-slope of the lateral leg. The lower flange and the first and second rib mating webs can, collectively, define a common distal end of the upper diverter.

Abstract: A fastener system that includes a female fastener assembly with a housing having a channel defined therein and a switch member movable within the channel between removing and fastening positions. The switch member includes a receiver portion having a post opening defined therein and a switch portion. The housing includes a lower opening. The post opening includes a removing portion that is aligned with the lower opening when the switch member is in the removing position and a fastening portion that is aligned with the post opening when the switch member is in the fastening position. The system also includes a male fastener assembly having a post with a slot therein. The post is received through the lower opening in the housing and the post opening so that the slot is aligned with the channel. The slot receives a portion of the receiver portion when the switch member is in the fastening position.

Abstract: A support structure for supporting loads on a sloping metal panel roof includes first and second side rails, an upper diverter, and a lower closure. An upstanding web of the upper diverter extends upwardly from the panel flat. An elongate lower flange extends from the upstanding web and is disposed against the metal roof panel. Opposing rib mating webs are on opposing sides of the lower flange. On a first side of the lower flange, a diversion leg of the lower flange is between the upstanding web and one of the rib mating webs. On the second side of the lower flange, the second rib mating web meets the upstanding web. The lower flange extends from the upstanding web to a distal end thereof up-slope of the lateral leg. The lower flange and the first and second rib mating webs can, collectively, define a common distal end of the upper diverter.

Abstract: A support structure for supporting loads on a sloping metal panel roof includes first and second side rails, an upper diverter, and a lower closure. An upstanding web of the upper diverter extends upwardly from the panel flat. An elongate lower flange extends from the upstanding web and is disposed against the metal roof panel. Opposing rib mating webs are on opposing sides of the lower flange. On a first side of the lower flange, a diversion leg of the lower flange is between the upstanding web and one of the rib mating webs. On the second side of the lower flange, the second rib mating web meets the upstanding web. The lower flange extends from the upstanding web to a distal end thereof up-slope of the lateral leg. The lower flange and the first and second rib mating webs can, collectively, define a common distal end of the upper diverter.

Abstract: A damping mechanism that includes a housing with an inner circumferential surface defined by an assembly outer race, an axle shaft that is rotatable with respect to the housing, and a transmission assembly operatively associated with the axle shaft and disposed within the housing. The transmission assembly includes an assembly intermediate race. A fluid space that includes fluid therein is defined between the assembly intermediate race and the inner circumferential surface of the assembly outer race. A vane is disposed between the assembly intermediate race and the inner circumferential surface of the assembly outer race. The vane includes a restriction space defined therein. When the axle shaft rotates in the first direction, the transmission assembly transmits rotation from the axle shaft to the vane, and when the axle shaft rotates in the second direction, the transmission assembly transmits less rotation to the first vane than when the axle shaft rotates in the first direction.

Abstract: A light-transmitting roof panel assembly, having the same shape as adjoining metal roof panels in a standing seam metal roof, includes an outer transparent panel made of a polymeric material and an inner reinforcing panel made of perforated metal. The inner and outer panels nest together and lie flush with the roof. Crimpable side corrugation pieces are attached to the reinforcing panel so that the assembly can be connected to neighboring roof panels by seaming.

Abstract: A light-transmitting roof panel assembly, having the same shape as adjoining metal roof panels in a standing seam metal roof, includes an outer transparent panel made of a polymeric material and an inner reinforcing panel made of perforated metal. The inner and outer panels nest together and lie flush with the roof. Crimpable side corrugation pieces are attached to the reinforcing panel so that the assembly can be connected to neighboring roof panels by seaming.

Abstract: A method to screen individuals specifically for paramagnetic or ferromagnetic objects they may be carrying or wearing, before they enter the high-field region of an MRI suite. The device used comprises either a screening portal or a compact, hand-held magnetic gradiometer and its electronics. The method places all of the sensor arrays in close proximity to all parts of a subject's body, for screening purposes.

Abstract: A roof curb is shipped in a disassembled state to an installer who assembles, sizes, locates and configures the curb to accommodate slope on any roof without welding or metal cutting. The curb includes an aluminum walls, each having a channel for receiving the bottom edge of a board, which may be taper cut according to the pitch of the roof to provide a level surface for supporting an appliance. Methods of making and installing the roof curb also are disclosed.