Abstract: An adapter includes a base connectable to an anesthetic agent container, a spout that extends from the base and defines at least one flow path therethrough, and a valve assembly disposed within the at least one flow path, the valve assembly being moveable between a first open position and a second closed position. The adapter also includes a radially expandable seal disposed about the spout, the seal having a first end, a second end, and an intermediate region between the first and second ends that expands radially outward relative to a longitudinal axis of the spout. The valve assembly has a surface that cooperates with the seal, wherein the cooperation between the surface and the seal expands the intermediate region radially outward relative to the longitudinal axis with the valve assembly in the first position.

Abstract: Adapters are provided for establishing fluid communication between an anesthetic agent container and an anesthetic vaporizer having a fluid port. The adapter may be mountable on the vaporizer to cooperate with the spout of an anesthetic agent container or may be mountable on an anesthetic agent container to cooperate with the fluid port of an anesthetic vaporizer to provide a sealing and/or retaining relationship therebetween.

Abstract: An integrated cartridge for automated sample manipulation and, particularly strand displacement amplification, is provided. The cartridge comprises a sealed, two-part device with internal fluid channels and chambers, as well as reagents. The cartridge performs the sequence of fluid transfers, reagent additions and heat transitions, such as those of the strand displacement amplification process, in a single, sealed device.