Patents by Inventor Richard Michael Day
Richard Michael Day has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240042056Abstract: The invention relates to a method for attaching a non-soluble active pharmaceutical ingredient (API) to a micro sphere produced by thermally induced phase separation (TIPS) comprising: i) mixing the micro sphere with an aqueous solution to form a first composition; ii) dissolving the non-soluble API in a first solvent and subsequently adding the non soluble API dissolved in the first solvent to the first composition to form a second composition; and iii) mixing the second composition. The invention further relates to a micro sphere produced by thermally induced phase separation which has a non-soluble API bound to its surface and a composition comprising said micro sphere for use in therapy.Type: ApplicationFiled: September 25, 2020Publication date: February 8, 2024Inventor: Richard Michael Day
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Patent number: 10864163Abstract: The invention relates to methods for attaching therapeutic agents to structures produced by thermally induced phase separation as well as methods for coating devices and producing multi-layered microspheres.Type: GrantFiled: December 22, 2014Date of Patent: December 15, 2020Assignee: UCL Business LTDInventor: Richard Michael Day
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Publication number: 20180028570Abstract: The disclosure relates to methods for obtaining angiogenic factors, as well as to methods of treating cardiovascular disease and methods for stimulating angiogenesis.Type: ApplicationFiled: July 27, 2017Publication date: February 1, 2018Applicant: UCL Business PLCInventor: Richard Michael Day
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Publication number: 20160296472Abstract: The invention relates to methods for attaching therapeutic agents to structures produced by thermally induced phase separation as well as methods for coating devices and producing multi-layered microspheres.Type: ApplicationFiled: December 22, 2014Publication date: October 13, 2016Applicant: UCL Business PLCInventor: Richard Michael DAY
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Patent number: 8815076Abstract: A method and system is provided to allow for determination of substantially Hematocrit independent analyte concentration. In one example, an analyte measurement system is provided that includes a test strip and a test meter. The test strip includes a reference electrode and a working electrode, in which the working electrode is coated with a reagent layer. The test meter includes an electronic circuit and a signal processor. The electronic circuit applies a plurality of voltages to the reference electrode and the working electrode over respective durations. The signal processor is configured to determine a substantially hematocrit-independent concentration of the analyte from a plurality of current values as measured by the processor upon application of a plurality of test voltages to the reference and working electrodes over a plurality of durations interspersed with rest voltages lower than the test voltages being applied to the electrodes.Type: GrantFiled: October 10, 2012Date of Patent: August 26, 2014Assignee: Lifescan Scotland LimitedInventors: Marco F. Cardosi, Stephen Patrick Blythe, Matthew Finch, Arlene Thompson, Nina Antonia Naylor, Eric Jason Bailey, Michael Patick Dolan, Gretchen Anderson, Lorraine Comstock, Mary McEvoy, Thomas Sutton, Richard Michael Day, Leanne Mills, Emma Vanessa Jayne Day, Christopher Philip Leach
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Patent number: 8765182Abstract: The invention relates to the production of microspheres having radial pores using thermally induced phase separation, especially microspheres for use in tissue engineering.Type: GrantFiled: June 20, 2008Date of Patent: July 1, 2014Assignee: UCL Business PLCInventors: Richard Michael Day, Jonny Blaker
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Patent number: 8486244Abstract: Described herein is an electrochemical enzymatic analyte test strip and method for making the test strip. The test strip utilizes isolated conductive areas inside the electrodes to define electrode whiskers. The method utilizes laser ablation to define electrode patterns.Type: GrantFiled: December 22, 2009Date of Patent: July 16, 2013Assignee: LifeScan Scotland LimitedInventors: Marco F. Cardosi, Leanne Mills, Emma Vanessa Jayne Day, Richard Michael Day, Christopher Philip Leach
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Patent number: 8460537Abstract: A method for determining an analyte concentration in blood is described that reduces the effects of hematocrit using a test strip attached to a test meter. The test strip includes a working electrode and a reference electrode. The test meter applies a test voltage between the working electrode and the reference electrode. After a user applies a blood sample containing an analyte onto the test strip, the test meter measures a plurality of test currents for a test time interval.Type: GrantFiled: September 3, 2009Date of Patent: June 11, 2013Assignee: LifeScan Scotland LimitedInventors: Stephen Patrick Blythe, Marco F Cardosi, Leanne Mills, Manuel Alvarez-Icaza, Emma Vanessa Jayne Day, Richard Michael Day, Christopher Philip Leach
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Patent number: 8293096Abstract: A method and system is provided to allow for determination of substantially Hematocrit independent analyte concentration. In one example, an analyte measurement system is provided that includes a test strip and a test meter. The test strip includes a reference electrode and a working electrode, in which the working electrode is coated with a reagent layer. The test meter includes an electronic circuit and a signal processor. The electronic circuit applies a plurality of voltages to the reference electrode and the working electrode over respective durations. The signal processor is configured to determine a substantially hematocrit-independent concentration of the analyte from a plurality of current values as measured by the processor upon application of a plurality of test voltages to the reference and working electrodes over a plurality of durations interspersed with rest voltages lower than the test voltages being applied to the electrodes.Type: GrantFiled: January 22, 2010Date of Patent: October 23, 2012Assignee: LifeScan Scotland LimitedInventors: Marco F. Cardosi, Stephen Patrick Blythe, Matthew Finch, Arlene Thompson, Nina Antonia Naylor, Eric Jason Bailey, Michael Patrick Dolan, Gretchen Anderson, Lorraine Comstock, Mary McEvoy, Thomas Sutton, Richard Michael Day, Leanne Mills, Emma Vanessa Jayne Day, Christopher Philip Leach
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Patent number: 8086415Abstract: A computer aided rational molecular design method that includes establishing a virtual library of functional monomers each having a portion that is capable of polymerizing and a functional group that is capable of interacting with a template molecule with the aid of a computer, designing a molecular model of a biological template molecule by a computer facilitated molecular mechanical method and screening said virtual library of functional monomers and selecting those monomers which have the highest binding score to the template molecule by their functional group.Type: GrantFiled: November 1, 2007Date of Patent: December 27, 2011Assignee: Cranfield UniversityInventors: Beining Chen, Richard Michael Day, Sreenath Subrahmanyam, Sergiy Anatoliyovich Piletsky, Olena Volodimirivna Piletska, Anthony Peter Francis Turner
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Publication number: 20110162978Abstract: A method and system is provided to allow for determination of substantially Hematocrit independent analyte concentration. In one example, an analyte measurement system is provided that includes a test strip and a test meter. The test strip includes a reference electrode and a working electrode, in which the working electrode is coated with a reagent layer. The test meter includes an electronic circuit and a signal processor. The electronic circuit applies a plurality of voltages to the reference electrode and the working electrode over respective durations. The signal processor is configured to determine a substantially hematocrit-independent concentration of the analyte from a plurality of current values as measured by the processor upon application of a plurality of test voltages to the reference and working electrodes over a plurality of durations interspersed with rest voltages lower than the test voltages being applied to the electrodes.Type: ApplicationFiled: January 22, 2010Publication date: July 7, 2011Applicant: LifeScan Scotland Ltd.Inventors: Marco F. CARDOSI, Stephen Patrick Blythe, Matthew Finch, Arlene Thompson, Nina Antonia Naylor, Eric Jason Bailey, Michael Patrick Dolan, Gretchen Anderson, Lorraine Comstock, Mary Mcevoy, Thomas Sutton, Richard Michael Day, Leanne Mills, Emma Vanessa Jayne Day, Christopher Philip Leach
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Publication number: 20110005941Abstract: A method for determining an analyte concentration in blood is described that reduces the effects of hematocrit using a test strip attached to a test meter. The test strip includes a working electrode and a reference electrode. The test meter applies a test voltage between the working electrode and the reference electrode. After a user applies a blood sample containing an analyte onto the test strip, the test meter measures a plurality of test currents for a test time interval.Type: ApplicationFiled: September 3, 2009Publication date: January 13, 2011Applicant: LifeScan Scotland Ltd.Inventors: Stephen Patrick BLYTHE, Marco F. Cardosi, Leanne Mills, Manuel Alvarez-Icaza, Emma Vanessa Jayne Day, Richard Michael Day, Christopher Philip Leach
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Publication number: 20100247663Abstract: The invention relates to the production of microspheres having radial pores using thermally induced phase separation, especially microspheres for use in tissue engineering.Type: ApplicationFiled: June 20, 2008Publication date: September 30, 2010Applicant: KING'S COLLEGE LONDONInventors: Richard Michael Day, Jonny Blaker
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Publication number: 20100206727Abstract: Described herein is an analyte test strip and method for making the test strip. The test strip utilizes isolated conductive areas to define electrode whiskers. The method utilizes laser ablation to define electrode patterns.Type: ApplicationFiled: December 22, 2009Publication date: August 19, 2010Applicant: LifeScan Scotland LimitedInventors: Marco F. Cardosi, Leanne Mills, Emma Vanessa Jayne Day, Richard Michael Day, Christopher Philip Leach