Abstract: A mounting bracket assembly capable of operatively engaging an associated jounce tongue of an associated vehicle suspension and supporting a supplemental air spring assembly in spaced relation to an associated sprung or unsprung mass of the associated vehicle. The mounting bracket assembly can include a first bracket supported on the associated jounce tongue and a second bracket supported on the first bracket. A supplemental suspension system can include an air spring assembly and a mounting spring assembly. A supplemental suspension system kit is also included.

Abstract: A device for measuring near forward scatter caused by particulate matter in a fluid is disclosed. The device comprises, according to various embodiments, a transceiver and a reflector. The transceiver includes a light source and a detector. The reflector is positioned opposite the transceiver so that at least a portion of the fluid is present between the transceiver and the reflector. The reflector includes a front portion facing the transceiver. Optical energy from the light source incident upon the reflector is reflected towards the transceiver as a return beam of optical energy, wherein the detector senses primarily optical energy of the return beam that is scattered over a range of near forward angles by particulate matter in the fluid.

Abstract: A motorcycle trailer has a wheeled frame which may be hitched to and unhitched from a towing motorcycle. The frame has a towbar which is movable from a projected position in which it may be hitched to the motorcycle to a retracted position in which it underlies the frame. The frame or the towbar has a handle which may be grasped by a person to enable the frame and the container conjointly to be towed by a person in a manner similar to that of a wheeled suitcase. When unhitched from the motorcycle, the frame and container may be maintained in either an upright or horizontal position.

Abstract: The present invention provides compositions, kits, assemblies, libraries, arrays, and high throughput methods for large scale structural and functional characterization of gene expression regulatory elements in a genome of an organism, especially in a human genome. In one aspect of the invention, an array of expression constructs is provided, each of the expression constructs comprising: a nucleic acid segment operably linked with a reporter sequence in an expression vector such that expression of the reporter sequence is under the transcriptional control of the nucleic acid segment, the nucleic acid segment varying in the library and having a diversity of at least 50. The nucleic acid segments can be a large library of gene expression regulatory elements such as transcriptional promoters. The present invention can have a wide variety of applications such as in personalized medicine, pharmacogenomics, and correlation of polymorphisms with phenotypic traits.

Abstract: A device for measuring near forward scatter caused by particulate matter in a fluid is disclosed. The device comprises, according to various embodiments, a transceiver and a reflector. The transceiver includes a light source and a detector. The reflector is positioned opposite the transceiver so that at least a portion of the fluid is present between the transceiver and the reflector. The reflector includes a front portion facing the transceiver. Optical energy from the light source incident upon the reflector is reflected towards the transceiver as a return beam of optical energy, wherein the detector senses primarily optical energy of the return beam that is scattered over a range of near forward angles by particulate matter in the fluid.

Abstract: The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia and mood disorders such as major depression disorder and bipolar disorder). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.

Abstract: The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.

Abstract: A method and apparatus are provided for controlling power hop in a Hotchkiss-type vehicle suspension having a live axle housing supported by a left and right suspension leaf spring, through the use of a pair of half-leaf springs adapted for operative attachment at a rear end thereof to the left and right terminal ends respectively of the axle housing, and a damping device adapted for operative attachment between a chassis of the vehicle and the rear axle housing. The half-leaf spring members extend longitudinally in a forward direction, below and generally in vertical alignment with their respectively associated suspension leaf spring, and are spaced therefrom, with the forward end of each half-spring member including a snubber for contacting a lower surface of the associated suspension leaf spring and terminating below and adjacent the forward end of its respectively associated suspension leaf spring.

Abstract: A device for measuring near forward scatter caused by particulate matter in a fluid is disclosed. The device comprises, according to various embodiments, a transceiver and a reflector. The transceiver includes a light source and a detector. The reflector is positioned opposite the transceiver so that at least a portion of the fluid is present between the transceiver and the reflector. The reflector includes a front portion facing the transceiver. Optical energy from the light source incident upon the reflector is reflected towards the transceiver as a return beam of optical energy, wherein the detector senses primarily optical energy of the return beam that is scattered over a range of near forward angles by particulate matter in the fluid.

Abstract: The present invention provides methods for diagnosing mental disorders (e.g., psychotic disorders such as schizophrenia). The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.

Abstract: A surgical valve includes a housing with a proximal housing portion and a distal housing portion cooperating to define a gel cavity. A seal material is disposed in the gel cavity and includes a gel having flow characteristics and incompressible characteristics. A distal guide tube is provided to facilitate retrograde insertion of a surgical instrument into the seal material. During assembly, pressure is applied by the housing portions to the seal material in order to form a circumferential seal and to close an instrument channel. Manufacture can be facilitated by use of a mandrel for maintaining the structural elements in axial alignment. Complimentary screw threads disposed between the first and second housing portions can be used to pressurize the gel and thereby create a locking force on an inserted instrument. Detented tabs can be provided to facilitate control of this locking force.

Abstract: A collapsible display 1 for a retail outlet is disclosed. The display 1 comprises a body portion 2 having a folded condition and an unfolded condition, and a display portion 3 including a display area 15 for carrying display information. Product supporting shelf portions 4 are pivotably connected between the body portion 2 and display portion 3, such that the display portion 3 is moveable relative to the body portion 2 between a first position, in which the shelf portion 4 are folded flat against the body portion 2 to allow folding of the body portion 2 to its folded condition, and a second position, in which the shelf portions 4 are adapted to support at least one product to be displayed and to retain the body portion 2 in its unfolded condition with the display area 15 protruding from the body portion 2.

Abstract: The present invention provides methods for diagnosing mental disorders such as mood disorders, including bipolar disorder I and II and major depression. The invention also provides methods of identifying modulators of such mental disorders as well as methods of using these modulators to treat patients suffering from such mental disorders.

Abstract: The present invention is directed towards a powdered dietary supplement formulation consisting essentially of a combination of freeze-dried fruits, vegetables and spices, wherein the formulation is prepared as a drink, tablet or capsule. The tablet may also be in chewable form.

Abstract: Niobium, Nb, is refined from FeNb by electron beam melt refining. The amount of the impurities in the FeNb which form suboxides with oxygen is optionally determined. Sufficient oxygen is added to form oxides with these impurities. The electron beam melt refining process is carried out at a sufficiently high temperature and under a sufficiently low vacuum so that the impurities are removed as oxides from the liquid Nb and the purified Nb is recovered. Preferably the oxygen is added as an oxygen-containing compound such as Nb.sub.2 O.sub.5. The recovered Nb can be subjected to additional electron beam melt refining cycles to obtain the desired purity.

Abstract: A thin window that stands off atmospheric pressure is fabricated using photolithographic and wet chemical etching techniques and comprises at least two layers: an etch stop layer and a protective barrier layer. The window structure also comprises a series of support ribs running the width of the window. The windows are typically made of boron-doped silicon and silicon nitride and are useful in instruments such as electron beam guns and x-ray detectors. In an electron beam gun, the window does not impede the electrons and has demonstrated outstanding gun performance and survivability during the gun tube manufacturing process.

Abstract: In a method for monitoring particulates in stacks or ducts a back-scatter monitor uses a solid-state laser to emit a collimated beam, the intensity of which is controlled via feedback from a reference detector. The beam is split so that part goes to a reference surface for calibration checks, and part is directed to pass at a selected angle through a gaseous sample. Optical energy scattered from particles in the sample is detected by viewing optics to provide an indication of particulate concentration. The beam steering mechanism can direct the optics to view scattering along a selectable axis that intersects the laser beam at a specified location within the gaseous sample. The method can be used to determine the opacity of the gaseous sample providing a basis for correlation to particulate loading of that portion of the particulates that are of a size comparable to the wavelength of light.

Abstract: A method for separating, identifying and purifying small, conotoxin-like rigidly conformed peptides ("conopeptides") containing multiple Cys residues comprises forming a conoeffector library, each member of which has a nucleic acid encoding a potential conopeptide sequence. The conoeffectors are expressed such that they are exposed on the surface of a bacteriophage. These bacteriophage are screened for binding to a target protein molecule, and receptors in particular, to separate and bind phage having affinity for the target protein. Reiterative screening, if required, is used to enrich and yield a phage carrying the bound conopeptide of the desired specificity and affinity. The enriched phage are then subjected to DNA sequencing to determine the conopeptide sequence including the position of the Cys residues.

Abstract: An improved method of monitoring particulates in stacks or ducts utilizes transmissometer/particulate monitor of the type which has an optical assembly containing a solid state light source of visible light such as a light-emitting diode or a solid-state laser. The light source emits a collimated beam that is split, part of which is focused onto a reference detector that monitors the intensity of the light source, while the other part is directed to a beam-steering apparatus that causes the beam to accurately pass through a gaseous sample to a desired location such as a retro-reflector. A position-sensing detector is used in a closed-loop manner to control the beam-steering apparatus. The ratio of the total energy of the detected light beam, relative to the reference detector output, is used to determine the opacity of the gaseous sample for the purpose of providing a basis for correlation to particulate loading of that portion of the particulates that are of a size comparable to the wavelength of light.

Abstract: An improved transmissometer/particulate monitor of the type which has an optical assembly containing a solid state light source preferably a solid-state laser. The light source emits a collimated beam that is split, part of which is focused onto a reference detector that monitors the intensity of the light source, while the other part is directed to a beam-steering apparatus that causes the beam to accurately pass through a gaseous sample to a desired location such as a retro-reflector. A position-sensing detector is used in a closed-loop manner to control the beam-steering apparatus. The ratio of the total energy of the detected light beam, relative to the reference detector output, is used to determine the opacity of the gaseous sample or to provide a basis for correlation to particulate loading of the sample or both.