Patents by Inventor Richard N. Greenberg

Richard N. Greenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of diarrhea induced by escherichia coli heat-stable enterotoxin
    Patent number: 4701458
    Abstract: Substantially nontoxic materials such as cysteamine constituting a source of sulfhydryl groups are useful in inhibiting diarrhea induced by Escherichia coli heat-stable enterotoxin. Such materials block ST-induced secretion prior to the formation of cyclic GMP without interference with normal basal activity or metabolism and may inactivate ST itself by breaking disulfide bridges. Combinations of a substantially nontoxic material constituting a source of sulfhydryl groups and an alpha-2 adrenergic receptor, such as naphazoline, or berberine are also useful in inhibiting such diarrhea.
    Type: Grant
    Filed: February 7, 1985
    Date of Patent: October 20, 1987
    Assignee: St. Louis University
    Inventor: Richard N. Greenberg
  • Inhibition of diarrhea induced by Escherichia coli heat-stable enterotoxin
    Patent number: 4587265
    Abstract: Substantially nontoxic materials such as cysteamine constituting a source of sulfhydryl groups are useful in inhibiting diarrhea induced by Escherichia coli heat-stable enterotoxin. Such materials block ST-induced secretion prior to the formation of cyclic GMP without interference with normal basal activity or metabolism and may inactivate ST itself by breaking disulfide bridges.
    Type: Grant
    Filed: February 7, 1983
    Date of Patent: May 6, 1986
    Assignee: St. Louis University
    Inventor: Richard N. Greenberg