Patents by Inventor Richard N. M. Cornelussen

Richard N. M. Cornelussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11129988
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: September 28, 2021
    Assignee: Medtronic, Inc.
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
  • Publication number: 20190175914
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Application
    Filed: February 18, 2019
    Publication date: June 13, 2019
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
  • Patent number: 10207112
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: February 19, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Xiaohong Zhou, Lilian Kornet, Richard N. M. Cornelussen, Robert W. Stadler
  • Publication number: 20170216601
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Application
    Filed: April 6, 2017
    Publication date: August 3, 2017
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
  • Publication number: 20170028204
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 2, 2017
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
  • Patent number: 9468764
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: October 18, 2016
    Assignee: Medtronic, Inc.
    Inventors: Xiaochong Zhou, John Edward Burnes, Lilian Kornet, Richard N. M. Cornelussen
  • Patent number: 9227069
    Abstract: An implantable medical device senses atrial depolarizations having associated refractory periods thereafter and delivers electrical stimulation pulses during the associated refractory periods to stimulate the atrioventricular (AV) node to cause a prolonged conduction time of an atrial depolarization to a ventricular chamber. The device delivers a pacing pulse to a first ventricular chamber during the prolonged conduction time to cause a contraction and associated refractory period of the first ventricular chamber, the first ventricular chamber contraction occurring earlier than a contraction of a second ventricular chamber.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: January 5, 2016
    Assignee: Medtronic, Inc.
    Inventors: Vinayakrishnan Rajan, Richard N. M. Cornelussen, Berthold Stegemann, Lilian Kornet
  • Patent number: 9211413
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: December 15, 2015
    Assignee: Medtronic, Inc.
    Inventors: Paul D. Ziegler, Lilian Kornet, Xiaohong Zhou, Richard N. M. Cornelussen, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Alberto Della Scala
  • Patent number: 9155893
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: October 13, 2015
    Assignee: Medtronic, Inc.
    Inventors: Xiaohong Zhou, Lilian Kornet, Richard N. M. Cornelussen, Paul D. Ziegler, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
  • Patent number: 8888699
    Abstract: Methods for treating a patient and further to devices for performing such treatment, e.g., methods and devices to perturb at least one physiological system and deliver therapy to the patient based on the effects of such perturbation. For example, a method for using an implantable medical device is disclosed that involves a method for using an implantable medical device delivering electrical stimuli to an afferent nerve associated with the selected organ. The efferent electrical activity is monitored in an efferent nerve responsive to delivering electrical stimuli to the afferent nerve, the monitored efferent electrical activity includes an indirect component of a compound action potential (CAP). A status of the selected organ is assessed based upon the indirect component.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: November 18, 2014
    Assignee: Medtronic, Inc.
    Inventors: Hendrik Peter Johan Buschman, Richard N. M. Cornelussen, Michael Roland Scott Hill, Lilian Kornet, Simone Cornelia Maria Anna Ordelman, Petrus Hermanus Veltink
  • Publication number: 20140316486
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Application
    Filed: April 22, 2014
    Publication date: October 23, 2014
    Applicant: Medtronic, Inc.
    Inventors: Xiaohong Zhou, Lilian Kornet, Richard N.M. Cornelussen, Paul D. Ziegler, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
  • Patent number: 8805500
    Abstract: A method and medical device for delivering an atrial pacing pulse to an atrial chamber to generate an evoked atrial depolarization, delivering a stimulation pulse to an atrioventricular node during a stimulation window to increase a PR interval of the heart, the stimulation window having a start time corresponding to the delivered atrial pacing pulse so that the stimulation pulse is delivered during a refractory period corresponding to the evoked atrial depolarization, and delivering a ventricular pacing pulse to a first ventricular chamber during the increased PR interval to cause a contraction of the first ventricular chamber to occur prior to a contraction of a second ventricular chamber to increase dyssynchrony between the contraction of the first ventricular chamber and the contraction of the second ventricular chamber.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: August 12, 2014
    Assignee: Medtronic, Inc.
    Inventors: Vinayakrishnan Rajan, Richard N. M. Cornelussen, Berthold Stegemann, Lilian Kornet
  • Patent number: 8781583
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: July 15, 2014
    Assignee: Medtronic, Inc.
    Inventors: Richard N. M. Cornelussen, Xiaohong Zhou, Robert Stadler, Lilian Kornet
  • Patent number: 8781582
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: July 15, 2014
    Assignee: Medtronic, Inc.
    Inventors: Paul D. Ziegler, Lilian Kornet, Xiaohong Zhou, Richard N. M. Cornelussen, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Alberto Della Scala
  • Publication number: 20140142650
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: Medtronic, Inc.
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
  • Patent number: 8725259
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: May 13, 2014
    Assignee: Medtronic, Inc.
    Inventors: Lilian Kornet, Richard N. M. Cornelussen, Paul D. Ziegler, Xiaohong Zhou, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
  • Patent number: 8718763
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: May 6, 2014
    Assignee: Medtronic, Inc.
    Inventors: Xiaohong Zhou, Robert Stadler, Richard N. M. Cornelussen, Lilian Kornet, Paul D. Ziegler, Karen J. Kleckner, Alberto Della Scala
  • Publication number: 20140114163
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Application
    Filed: December 23, 2013
    Publication date: April 24, 2014
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
  • Patent number: 8706223
    Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: April 22, 2014
    Assignee: Medtronic, Inc.
    Inventors: Xiaohong Zhou, Lilian Kornet, Richard N. M. Cornelussen, Paul D. Ziegler, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
  • Patent number: 8639327
    Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: January 28, 2014
    Assignee: Medtronic, Inc.
    Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N. M. Cornelussen