Patents by Inventor Richard N. M. Cornelussen
Richard N. M. Cornelussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11129988Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: GrantFiled: February 18, 2019Date of Patent: September 28, 2021Assignee: Medtronic, Inc.Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
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Publication number: 20190175914Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: ApplicationFiled: February 18, 2019Publication date: June 13, 2019Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
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Patent number: 10207112Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: GrantFiled: April 6, 2017Date of Patent: February 19, 2019Assignee: MEDTRONIC, INC.Inventors: Xiaohong Zhou, Lilian Kornet, Richard N. M. Cornelussen, Robert W. Stadler
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Publication number: 20170216601Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: ApplicationFiled: April 6, 2017Publication date: August 3, 2017Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
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Publication number: 20170028204Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: ApplicationFiled: October 17, 2016Publication date: February 2, 2017Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
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Patent number: 9468764Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: GrantFiled: January 27, 2014Date of Patent: October 18, 2016Assignee: Medtronic, Inc.Inventors: Xiaochong Zhou, John Edward Burnes, Lilian Kornet, Richard N. M. Cornelussen
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Patent number: 9227069Abstract: An implantable medical device senses atrial depolarizations having associated refractory periods thereafter and delivers electrical stimulation pulses during the associated refractory periods to stimulate the atrioventricular (AV) node to cause a prolonged conduction time of an atrial depolarization to a ventricular chamber. The device delivers a pacing pulse to a first ventricular chamber during the prolonged conduction time to cause a contraction and associated refractory period of the first ventricular chamber, the first ventricular chamber contraction occurring earlier than a contraction of a second ventricular chamber.Type: GrantFiled: March 15, 2011Date of Patent: January 5, 2016Assignee: Medtronic, Inc.Inventors: Vinayakrishnan Rajan, Richard N. M. Cornelussen, Berthold Stegemann, Lilian Kornet
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Patent number: 9211413Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: July 14, 2014Date of Patent: December 15, 2015Assignee: Medtronic, Inc.Inventors: Paul D. Ziegler, Lilian Kornet, Xiaohong Zhou, Richard N. M. Cornelussen, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Alberto Della Scala
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Patent number: 9155893Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: April 22, 2014Date of Patent: October 13, 2015Assignee: Medtronic, Inc.Inventors: Xiaohong Zhou, Lilian Kornet, Richard N. M. Cornelussen, Paul D. Ziegler, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
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Patent number: 8888699Abstract: Methods for treating a patient and further to devices for performing such treatment, e.g., methods and devices to perturb at least one physiological system and deliver therapy to the patient based on the effects of such perturbation. For example, a method for using an implantable medical device is disclosed that involves a method for using an implantable medical device delivering electrical stimuli to an afferent nerve associated with the selected organ. The efferent electrical activity is monitored in an efferent nerve responsive to delivering electrical stimuli to the afferent nerve, the monitored efferent electrical activity includes an indirect component of a compound action potential (CAP). A status of the selected organ is assessed based upon the indirect component.Type: GrantFiled: April 26, 2011Date of Patent: November 18, 2014Assignee: Medtronic, Inc.Inventors: Hendrik Peter Johan Buschman, Richard N. M. Cornelussen, Michael Roland Scott Hill, Lilian Kornet, Simone Cornelia Maria Anna Ordelman, Petrus Hermanus Veltink
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Publication number: 20140316486Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: ApplicationFiled: April 22, 2014Publication date: October 23, 2014Applicant: Medtronic, Inc.Inventors: Xiaohong Zhou, Lilian Kornet, Richard N.M. Cornelussen, Paul D. Ziegler, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
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Patent number: 8805500Abstract: A method and medical device for delivering an atrial pacing pulse to an atrial chamber to generate an evoked atrial depolarization, delivering a stimulation pulse to an atrioventricular node during a stimulation window to increase a PR interval of the heart, the stimulation window having a start time corresponding to the delivered atrial pacing pulse so that the stimulation pulse is delivered during a refractory period corresponding to the evoked atrial depolarization, and delivering a ventricular pacing pulse to a first ventricular chamber during the increased PR interval to cause a contraction of the first ventricular chamber to occur prior to a contraction of a second ventricular chamber to increase dyssynchrony between the contraction of the first ventricular chamber and the contraction of the second ventricular chamber.Type: GrantFiled: March 15, 2011Date of Patent: August 12, 2014Assignee: Medtronic, Inc.Inventors: Vinayakrishnan Rajan, Richard N. M. Cornelussen, Berthold Stegemann, Lilian Kornet
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Patent number: 8781582Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: January 19, 2012Date of Patent: July 15, 2014Assignee: Medtronic, Inc.Inventors: Paul D. Ziegler, Lilian Kornet, Xiaohong Zhou, Richard N. M. Cornelussen, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Alberto Della Scala
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Patent number: 8781583Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: January 19, 2012Date of Patent: July 15, 2014Assignee: Medtronic, Inc.Inventors: Richard N. M. Cornelussen, Xiaohong Zhou, Robert Stadler, Lilian Kornet
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Publication number: 20140142650Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: ApplicationFiled: January 27, 2014Publication date: May 22, 2014Applicant: Medtronic, Inc.Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
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Patent number: 8725259Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: January 19, 2012Date of Patent: May 13, 2014Assignee: Medtronic, Inc.Inventors: Lilian Kornet, Richard N. M. Cornelussen, Paul D. Ziegler, Xiaohong Zhou, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
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Patent number: 8718763Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: January 19, 2012Date of Patent: May 6, 2014Assignee: Medtronic, Inc.Inventors: Xiaohong Zhou, Robert Stadler, Richard N. M. Cornelussen, Lilian Kornet, Paul D. Ziegler, Karen J. Kleckner, Alberto Della Scala
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Publication number: 20140114163Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: ApplicationFiled: December 23, 2013Publication date: April 24, 2014Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N.M. Cornelussen
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Patent number: 8706223Abstract: The disclosure herein relates generally to methods for treating heart conditions using vagal stimulation, and further to systems and devices for performing such treatment. Such methods may include monitoring physiological parameters of a patient, detecting cardiac conditions, and delivering vagal stimulation (e.g., electrical stimulation to the vagus nerve or neurons having parasympathetic function) to the patient to treat the detected cardiac conditions.Type: GrantFiled: January 19, 2012Date of Patent: April 22, 2014Assignee: Medtronic, Inc.Inventors: Xiaohong Zhou, Lilian Kornet, Richard N. M. Cornelussen, Paul D. Ziegler, Robert Stadler, Eduardo Warman, Karen J. Kleckner, Lucy Nichols, Alberto Della Scala
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Patent number: 8639327Abstract: Methods of nerve signal differentiation, methods of delivering therapy using such nerve signal differentiation, and to systems and devices for performing such methods. Nerve signal differentiation may include locating two electrodes proximate nerve tissue and differentiating between efferent and afferent components of nerve signals monitored using the two electrodes.Type: GrantFiled: July 30, 2010Date of Patent: January 28, 2014Assignee: Medtronic, Inc.Inventors: Xiaohong Zhou, John Edward Burnes, Lilian Kornet, Richard N. M. Cornelussen