Patents by Inventor Richard P. Creagan

Richard P. Creagan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of inactivated viral vaccines
    Patent number: 5106619
    Abstract: Vaccines employing inactivated viruses having improved retention of antigenic characteristics are prepared by psoralen-inactivation of the live virus in a non-oxidizing atmosphere. By excluding oxygen and other oxidizing species from the inactivation medium, degradation of the antigen characteristics resulting from irradiation with ultraviolet light is largely prevented. The resulting inactivated viruses are employed in vaccine preparations for the inoculation of susceptible hosts to inhibit viral infection.
    Type: Grant
    Filed: January 10, 1990
    Date of Patent: April 21, 1992
    Assignee: Diamond Scientific Co.
    Inventors: Gary P. Wiesehahn, Richard P. Creagan, David R. Stevens, Richard Giles
  • Photochemical decontamination treatment of whole blood or blood components
    Patent number: 4727027
    Abstract: Biological compositions are decontaminated by treatment with furocoumarin derivatives and irradiation under particular conditions in which the proteins retain their original physiological activities and any pathogenic microorganisms and polynucleotide fragments thereof are rendered inactive. It has been found that reduction of the amount of dissolved oxygen in the treatment solution substantially inhibits denaturation of the proteins.
    Type: Grant
    Filed: October 7, 1985
    Date of Patent: February 23, 1988
    Assignee: Diamond Scientific Co.
    Inventors: Gary P. Wiesehahn, Richard P. Creagan
  • Preparation of inactivated viral vaccines
    Patent number: 4693981
    Abstract: Vaccines employing inactivated viruses having improved retention of antigenic characteristics are prepared by psoralen-inactivation of the live virus in a non-oxidizing atmosphere. By excluding oxygen and other oxidizing species from the inactivation medium, degradation of the antigen characteristics resulting from irradiation with ultraviolet light is largely prevented. The resulting inactivated viruses are employed in vaccine preparations for the inoculation of susceptible hosts to inhibit viral infection.
    Type: Grant
    Filed: October 7, 1985
    Date of Patent: September 15, 1987
    Assignee: Advanced Genetics Research Institute
    Inventors: Gary P. Wiesehahn, Richard P. Creagan, David R. Stevens, Richard Giles