Abstract: Presently provided are inhibitors of TD02 and IDO1 and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2,3 dioxygenase and indoleamine 2,3-dioxygenase 1; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.

Abstract: A technology that streams graphical components and rendering instructions to a client device, for the client device to perform the final rendering and overlaying of that content onto the client's video stream based on the client's most recent tracking of the device's position and orientation. A client device sends a request for augmented reality drawing data to a network device. In response, the network device generates augmented reality drawing data, which can be augmented reality change data based on the augmented reality information and previous client render state information, and sends the augmented reality drawing data to the client device. The client device receives the augmented reality drawing data and renders a visible representation of an augmented reality scene comprising overlaying augmented reality graphics over a current video scene obtained from a camera of the client device.

Abstract: Systems and methods for optimizing drug management are disclosed. A disclosed system implements a method that includes receiving, from a first client system, a new drug code and drug information associated with new drug code, determining, by the computing system based on the received drug information, a predetermined medication and a first local identifier used by the first client system to identify the predetermined medication, determining, based at least in part on identifying the first local identifier, one or more second local identifiers that identify the predetermined medication, identifying, based on the one or more second local identifiers, a plurality of second client systems that use the one or more second local identifiers, and automatically providing, an instruction to each of the plurality of second client systems to associate, at the second client system, one or more corresponding second local identifiers with the new drug code.

Abstract: A technology that streams graphical components and rendering instructions to a client device, for the client device to perform the final rendering and overlaying of that content onto the client's video stream based on the client's most recent tracking of the device's position and orientation. A client device sends a request for augmented reality drawing data to a network device. In response, the network device generates augmented reality drawing data, which can be augmented reality change data based on the augmented reality information and previous client render state information, and sends the augmented reality drawing data to the client device. The client device receives the augmented reality drawing data and renders a visible representation of an augmented reality scene comprising overlaying augmented reality graphics over a current video scene obtained from a camera of the client device.

Abstract: A technology that streams graphical components and rendering instructions to a client device, for the client device to perform the final rendering and overlaying of that content onto the client's video stream based on the client's most recent tracking of the device's position and orientation. A client device sends a request for augmented reality drawing data to a network device. In response, the network device generates augmented reality drawing data, which can be augmented reality change data based on the augmented reality information and previous client render state information, and sends the augmented reality drawing data to the client device. The client device receives the augmented reality drawing data and renders a visible representation of an augmented reality scene comprising overlaying augmented reality graphics over a current video scene obtained from a camera of the client device.

Abstract: A technology that streams graphical components and rendering instructions to a client device, for the client device to perform the final rendering and overlaying of that content onto the client's video stream based on the client's most recent tracking of the device's position and orientation. A client device sends a request for augmented reality drawing data to a network device. In response, the network device generates augmented reality drawing data, which can be augmented reality change data based on the augmented reality information and previous client render state information, and sends the augmented reality drawing data to the client device. The client device receives the augmented reality drawing data and renders a visible representation of an augmented reality scene comprising overlaying augmented reality graphics over a current video scene obtained from a camera of the client device.

Abstract: A cleaning apparatus for cleaning a surface is disclosed. The cleaning apparatus includes a base portion for movement along a surface and a handle pivotally connected to the base portion. The apparatus further includes a solution tank for supplying a flow of cleaning solution to the surface. The solution tank is removably mounted to the handle. The apparatus further includes a recovery tank removably mounted one of the handle and the base portion and a suction nozzle secured to the base portion and in fluid communication with the recovery tank. The apparatus still further includes a suction source in fluid communication with the suction nozzle for generating suction to draw dirt and liquid through the suction nozzle and into the recovery tank and a tank carrying handle fixedly secured to the solution tank. The apparatus yet further includes a latch pivotally connected to the tank carrying handle and releasably connected to the handle for releasably latching the solution tank to the handle.

Abstract: A cleaning apparatus for cleaning a surface in which cleaning solution is dispensed to the surface and substantially simultaneously extracted along with the dirt on the surface in a continuous operation is provided. The cleaning apparatus includes a base portion for movement along the surface and a handle pivotally connected to the base portion. A solution tank for supplying a flow of cleaning solution to the surface is removably mounted to the handle. A recovery tank is removably mounted to the handle. A suction nozzle is secured to the base portion and in fluid communication with the recovery tank. A suction source is in fluid communication with the suction nozzle for generating suction to draw dirt and liquid through the suction nozzle and into the recovery tank. The recovery tank and solution tank are in an aligned stack arrangement when the handle is in both the upright and working positions.

Abstract: A cleaning apparatus for cleaning a surface in which cleaning solution is dispensed to the surface and substantially simultaneously extracted along with the dirt on the surface in a continuous operation is provided. In one aspect of the invention, the cleaning apparatus includes a housing and a recovery tank removably mounted to the housing. A solution tank for supplying a flow of cleaning solution to the surface is removably mounted to the housing. A suction nozzle is secured to the housing and is in fluid communication with the recovery tank. A suction source is in fluid communication with the suction nozzle for generating suction to draw dirt and liquid through the suction nozzle and into the recovery tank. A first latch is operatively connected to the solution tank to releasably latch the solution tank to the housing and a second latch is operatively connected to the recovery tank to releasably latch the recovery tank to said housing, wherein the second latch is in close proximity to the first latch.

Abstract: A cleaning apparatus for cleaning a surface in which cleaning solution is dispensed to the surface and substantially simultaneously extracted along with the dirt on the surface in a continuous operation is provided. The cleaning apparatus includes a base portion for movement along the surface and a handle pivotally connected to the base portion. A solution tank for supplying a flow of cleaning solution to the surface is removably mounted to a side of the handle. A recovery tank is removably mounted to the opposite side of the handle. A suction nozzle is secured to the base portion. A suction source is in fluid communication with the suction nozzle for generating suction to draw dirt and liquid through the suction nozzle and into the recovery tank.

Abstract: A cleaning apparatus for cleaning a surface in which cleaning solution is dispensed to the surface and substantially simultaneously extracted along with the dirt on the surface in a continuous operation is provided. The cleaning apparatus includes a base portion for movement along the surface and a handle pivotally connected to the base portion. The handle includes a lower portion and an upper portion pivotally connected to the lower portion and pivoted between an upper position for use and a lower position for storage. A solution tank for supplying a flow of cleaning solution to the surface is removably mounted to one of the base portion and the handle. A recovery tank removably mounted to one of the base portion and the handle and is in fluid communication with a suction nozzle secured to said base portion.

Abstract: A portable cleaning apparatus for cleaning a surface is provided and includes a housing for movement along the surface. A solution container is mounted to the housing and contains a solution. A dispensing nozzle is provided on the housing and is fluidly connected to the solution container. The dispensing nozzle dispenses solution beyond the edge of the housing. In one aspect, an edge cleaner is provided at an edge of the housing and includes a plurality of pliable elements for agitating the surface, wherein the pliable elements contact the surface beyond the edge of said housing.

Abstract: Monotectic alloys having aligned spherical particles or rods of the minor component dispersed in a matrix of the major component are prepared by forming a melt containing predetermined amounts of the major and minor components of a chosen monotectic system, providing in the melt a dopant capable of breaking down the liquid-solid interface for the chosen alloy, and directionally solidifying the melt at a selected temperature gradient and a selected rate of movement of the liquid-solid interface (growth rate). Shaping of the minor component into spheres or rods and the spacing therebetween are controlled by the amount of dopant and the temperature gradient and growth rate values. Specific alloy systems include Al-Bi,Al-Pb and Zn-Bi, using a transition element such as iron.