Patents by Inventor Richard Peter Trezza

Richard Peter Trezza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for measuring T cell cytokines
    Patent number: 6410252
    Abstract: The present invention relates to devices and methods for detecting cellular products, and in particular for measuring secreted cellular products, including cytokines. Microwells comprising hydrophobic membranes are described having greater capability to detect cytokines from individual cells in a mixture of heterogeneous cells.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: June 25, 2002
    Assignee: Case Western Reserve University
    Inventors: Paul V. Lehmann, Alexey Karulin, Richard Peter Trezza, Thomas Forsthuber
  • Detecting alloreactivity
    Patent number: 5939281
    Abstract: The present invention relates to devices and methods for detecting cellular products, and in particular for measuring secreted cellular products, including cytokines. Microwells comprising hydrophobic membranes are described having greater capability to detect cytokines from individual cells in a mixture of heterogeneous cells. A method is provided that can serve as a) a functional predictor of allograft survival in transplant recipients, and b) a tool for monitoring the level of immunosuppression in allograft recipients.
    Type: Grant
    Filed: September 16, 1996
    Date of Patent: August 17, 1999
    Assignee: Case Western Reserve University
    Inventors: Paul V. Lehmann, Alexey Karulin, Richard Peter Trezza