Patents by Inventor Richard Philion

Richard Philion has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions
    Patent number: 5707603
    Abstract: The invention provides targeting radioactive immunoreagents comprising a metal radionuclide ion, a complexing agent having structure A-I, as defined in the specification, and an immunoreactive group covalently bonded to the complexing agent. The present invention also provides novel complexing agents having the structure A-I, as defined in the specification. The targeting radioactive immunoreagents are particularly useful in therapeutic and diagnostic imaging compositions and methods.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: January 13, 1998
    Assignee: Nycomed Imaging AS
    Inventors: John L. Toner, David A. Hilborn, Bruce J. Murray, Timothy Z. Hossain, Robert A. Snow, Ashis K. Saha, Richard Philion, Clyde W. Shearman, Chandra Shah
  • Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene)bis?hydrazine caroximidamide!
    Patent number: 5693673
    Abstract: Process for the preparation of 2,2'-(1-methyl 1,2-ethanediylidene)bis?hydrazine carboximidamide! by:a) reacting aminoguanidine hydrochloride with methylglyoxal aldehyde or methylglyoxal dimethyl acetal; andb) purifying the 2,2'-(1-methyl-1,2-ethanediylidene)bis?hydrazine carboximidamide! by crystallization from an acidic aqueous-isopropyl alcohol medium.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: December 2, 1997
    Assignee: Sanofi
    Inventors: Richard Philion, Steven A. Elenbaas
  • Process of preparing 2,2'-(1-methyl-1,2-ethanediylidene) bis[hydrazinecarboximidamide]
    Patent number: 5659083
    Abstract: Process for the preparation of 2,2'-(1-methyl-1,2-ethanediylidine)bis[hydrazine carboximidamide] bya) removing impurities from aminoguanidine bicarbonate;b) reacting the aminoguanidine bicarbonate with methylglyoxal dimethyl acetal in an aqueous isopropyl medium; andc) purifying the 2,2'-(1-methyl-1,2-ethanediylidene)bis[hydrazine carboximidamide] by crystallization from an acidic aqueous-isopropanol medium.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: August 19, 1997
    Assignee: Sanofi
    Inventors: Richard Philion, Martin Robert Gray