Abstract: A personalized greeting card system includes a foldable sheet member defining first and second panels and a plurality of interchangeable sleeve elements for removably fitting over and around the second panel. Each of the sleeve elements is provided with a separate printed message or greeting. The first panel defines opposed front and rear surfaces, and the front surface has a printed message or greeting thereon which preferably includes a person's name. The rear surface has a plural-lined printed message or greeting thereon which uses the letters of the person's name as the first letter of each line of the plural-lined message.