Patents by Inventor Richard PLEMPER

Richard PLEMPER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC FUSED PYRAZOLE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY INFECTIONS INCLUDING RSV
    Publication number: 20240352013
    Abstract: Disclosed herein are compounds and compositions for inhibiting, treating or preventing respiratory infections, illnesses, diseases, and other respiratory conditions such as those caused by viruses including RSV, coronavirus, and related members of the pneumovirus and paramyxovirus families such as human metapneumovirus, mumps virus, human parainfluenzaviruses, and Nipah and hendra virus. Methods of inhibition, treatment or prevention of infections and diseases caused by these viruses are also provided.
    Type: Application
    Filed: July 29, 2022
    Publication date: October 24, 2024
    Inventors: Richard Plemper, Julien Sourimant
  • Inhibitors of RSV replication and applications thereof
    Patent number: 12016863
    Abstract: Disclosed herein are compounds having antiviral activity, and, in particular, an inhibitory activity on the replication of Respiratory Syncytial Virus (RSV). Druggable target sites, including Px, in the RSV N protein are disclosed, as well as compounds targeting Px. The compounds can be used to treat patients with RSV infection.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: June 25, 2024
    Assignees: Georgia State University Research Foundation, Inc., Emory University
    Inventors: Richard Plemper, Julien Sourimant, Edgars Jecs, Dennis Liotta, Stephen Pelly, Robert Wilson, Zackery Will Dentmon
  • SMALL MOLECULES POLYMERASE INHIBITORS
    Publication number: 20220411378
    Abstract: Disclosed herein are compounds using for inhibiting RNA polymerase, especially viral RNA polymerase. The compounds are effective for the treatment of viruses in Paramyxoviridae family, especially measles and human parainfluenza virus.
    Type: Application
    Filed: September 15, 2020
    Publication date: December 29, 2022
    Inventors: Robert COX, Richard PLEMPER, Benhur LEE
  • INHIBITORS OF RSV REPLICATION AND APPLICATIONS THEREOF
    Publication number: 20210244740
    Abstract: Disclosed herein are compounds having antiviral activity, and, in particular, an inhibitory activity on the replication of Respiratory Syncytial Virus (RSV). Druggable target sites, including Px, in the RSV N protein are disclosed, as well as compounds targeting Px. The compounds can be used to treat patients with RSV infection.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 12, 2021
    Inventors: Richard PLEMPER, Julien SOURIMANT, Edgars JECS, Dennis LIOTTA, Stephen PELLY, Robert WILSON, Zackery Will DENTMON
  • Tunable vaccine platform against pathogens of the paramyxovirus family
    Patent number: 10780158
    Abstract: Disclosed herein is a strategy for the engineering of recombinant vaccines against major human and animal pathogens of the paramyxovirus family. Also disclosed are recombinant virus able to replicate without being pathogenic. Also disclosed is a method of immunizing a subject against infection with a that involves administering to the subject a recombinant vaccine disclosed herein.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: September 22, 2020
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Richard Plemper, Veronika von Messling
  • TUNABLE VACCINE PLATFORM AGAINST PATHOGENS OF THE PARAMYXOVIRUS FAMILY
    Publication number: 20180326046
    Abstract: Disclosed herein is a strategy for the engineering of recombinant vaccines against major human and animal pathogens of the paramyxovirus family. Also disclosed are recombinant virus able to replicate without being pathogenic. Also disclosed is a method of immunizing a subject against infection with a that involves administering to the subject a recombinant vaccine disclosed herein.
    Type: Application
    Filed: November 16, 2016
    Publication date: November 15, 2018
    Inventors: Richard PLEMPER, Veronika VON MESSLING