Abstract: A liquid scintillation counting system employs a guard detector efficiency compensation system to adjust sample event counts to compensate for a non-ideal guard which may not detect all cosmic and environmental gamma background noise events. The system and method determines counts of events detected coincidently by a guard detector subsystem and a sample detector subsystem in one or more energy regions as well as counts of events that are detected by the sample detector subsystem and not coincidently detected by the guard detector subsystem for the respective energy regions. The system and method calculates correction values for the respective energy regions based on the counts of coincident and non-coincident events and the guard efficiency values associated with the respective energy regions, using, for example, a quenched or unquenched sample. The system then applies the calculated correction values to counts for the respective energy regions, to produce corrected sample event counts.

Abstract: A lab member for use in a laboratory liquid handling system including a pipetting module and a drive system, the pipetting module including first and second pipettors, the first and second pipettors including first and second pipettor shafts, respectively, a first pipetting tip extending from an end of the first pipettor shaft, and a second pipetting tip extending from an end of the second pipettor shaft, includes a lab object and first and second integral adapter structures. The first and second adapter structures are configured to engage the first and second pipettor shafts, respectively. The first adapter structure is configured to releasably secure the lab member to the first pipettor shaft.

Abstract: A liquid scintillation counting system employs a guard detector efficiency compensation system to adjust sample event counts to compensate for a non-ideal guard which may not detect all cosmic and environmental gamma background noise events. The system and method determines counts of events detected coincidently by a guard detector subsystem and a sample detector subsystem in one or more energy regions as well as counts of events that are detected by the sample detector subsystem and not coincidently detected by the guard detector subsystem for the respective energy regions. The system and method calculates correction values for the respective energy regions based on the counts of coincident and non-coincident events and the guard efficiency values associated with the respective energy regions, using, for example, a quenched or unquenched sample. The system then applies the calculated correction values to counts for the respective energy regions, to produce corrected sample event counts.

Abstract: A lab member for use in a laboratory liquid handling system including a pipetting module and a drive system, the pipetting module including first and second pipettors, the first and second pipettors including first and second pipettor shafts, respectively, a first pipetting tip extending from an end of the first pipettor shaft, and a second pipetting tip extending from an end of the second pipettor shaft, includes a lab object and first and second integral adapter structures. The first and second adapter structures are configured to engage the first and second pipettor shafts, respectively. The first adapter structure is configured to releasably secure the lab member to the first pipettor shaft.

Abstract: A lab member for use in a laboratory liquid handling system including a pipetting module and a drive system, the pipetting module including first and second pipettors, the first and second pipettors including first and second pipettor shafts, respectively, a first pipetting tip extending from an end of the first pipettor shaft, and a second pipetting tip extending from an end of the second pipettor shaft, includes a lab object and first and second integral adapter structures. The first and second adapter structures are configured to engage the first and second pipettor shafts, respectively. The first adapter structure is configured to releasably secure the lab member to the first pipettor shaft.

Abstract: A lab member for use in a laboratory liquid handling system including a pipetting module and a drive system, the pipetting module including first and second pipettors, the first and second pipettors including first and second pipettor shafts, respectively, a first pipetting tip extending from an end of the first pipettor shaft, and a second pipetting tip extending from an end of the second pipettor shaft, includes a lab object and first and second integral adapter structures. The first and second adapter structures are configured to engage the first and second pipettor shafts, respectively. The first adapter structure is configured to releasably secure the lab member to the first pipettor shaft.

Abstract: Methods and systems for automatically locating and identifying labware using radio-frequency identification (RFID) tags are described herein. The methods and systems include a plurality of RFID tags (pre-programmed with unique data codes) that are associated with labware (or labware holders). For example, the RFID tags can be embedded within the locating pegs of the labware (or labware holders). The methods and systems also include a plurality of RFID tag readers that mount near known locations of an instrument deck which receives the labware. The RFID tag readers automatically scan for the presence of RFID tags such that when a piece of labware is added to the instrument deck, and then report to a processing device the specific known location on deck where each tag was found, as well as the unique data code of each tag. Using this information, the methods and systems determine one or more of the location, orientation, and identity of the received labware.

Abstract: Methods, systems, and computer program products for measuring a capacitance between a probe and a liquid, pausing movement of the probe based on a rate of change of the capacitance, further measuring the capacitance while the probe is paused, and, based on the further measurements, performing one or more of: resuming movement of the probe, determining a position of the probe, aspirating liquid into the probe, and dispensing from the probe. Resuming movement of the probe can include returning iteratively to measuring a capacitance, and the further measuring can be performed for a time interval that can vary based on the further measured capacitance(s), a probe movement characteristic, and/or a sampling rate.

Abstract: Methods and systems for automatically locating and identifying labware using radio-frequency identification (RFID) tags are described herein. The methods and systems include a plurality of RFID tags (pre-programmed with unique data codes) that are associated with labware (or labware holders). For example, the RFID tags can be embedded within the locating pegs of the labware (or labware holders). The methods and systems also include a plurality of RFID tag readers that mount near known locations of an instrument deck which receives the labware. The RFID tag readers automatically scan for the presence of RFID tags such that when a piece of labware is added to the instrument deck, and then report to a processing device the specific known location on deck where each tag was found, as well as the unique data code of each tag. Using this information, the methods and systems determine one or more of the location, orientation, and identity of the received labware.

Abstract: Methods, systems, and computer program products for measuring a capacitance between a probe and a liquid, pausing movement of the probe based on a rate of change of the capacitance, further measuring the capacitance while the probe is paused, and, based on the further measurements, performing one or more of: resuming movement of the probe, determining a position of the probe, aspirating liquid into the probe, and dispensing from the probe. Resuming movement of the probe can include returning iteratively to measuring a capacitance, and the further measuring can be performed for a time interval that can vary based on the further measured capacitance(s), a probe movement characteristic, and/or a sampling rate.

Abstract: Methods and systems for automatically locating and identifying labware using radio-frequency identification (RFID) tags are described herein. The methods and systems include a plurality of RFID tags (pre-programmed with unique data codes) that are associated with labware (or labware holders). For example, the RFID tags can be embedded within the locating pegs of the labware (or labware holders). The methods and systems also include a plurality of RFID tag readers that mount near known locations of an instrument deck which receives the labware. The RFID tag readers automatically scan for the presence of RFID tags such that when a piece of labware is added to the instrument deck, and then report to a processing device the specific known location on deck where each tag was found, as well as the unique data code of each tag. Using this information, the methods and systems determine one or more of the location, orientation, and identity of the received labware.

Abstract: Methods, systems, and computer program products for measuring a capacitance between a probe and a liquid, pausing movement of the probe based on a rate of change of the capacitance, further measuring the capacitance while the probe is paused, and, based on the further measurements, performing one or more of: resuming movement of the probe, determining a position of the probe, aspirating liquid into the probe, and dispensing from the probe. Resuming movement of the probe can include returning iteratively to measuring a capacitance, and the further measuring can be performed for a time interval that can vary based on the further measured capacitance(s), a probe movement characteristic, and/or a sampling rate.