Abstract: Methods and materials for generating and using complexes that contain erythrocytes coupled to polypeptides, and particularly to erythrocyte-polypeptide complexes that can interact with biological molecules, are provided herein.

Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.

Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.

Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.

Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.

Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.

Abstract: Using a novel water-soluble, active ester amide-containing functionalized controlled radical polymerization initiator, stimuli responsive polymers have been grown from the surface of a protein, exemplified by chymotrypsin or any protein having surface amino acids that will covalently bind to the active ester amide-containing functionalized initiator. It is shown that changes in temperature or pH can change the conformation of the polymer surrounding the enzyme, which in turn enabled the rational tailoring of enzyme activity and stability. This method has afforded an increase in the activity and stability of the enzyme by an order of magnitude at pH's where the enzyme is usually inactive or unstable. Multimodal temperature responsive protein-block copolymer conjugates are described.

Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.

Abstract: Using a novel water-soluble, active ester amide-containing functionalized controlled radical polymerization initiator, stimuli responsive polymers have been grown from the surface of a protein, exemplified by chymotrypsin or any protein having surface amino acids that will covalently bind to the active ester amide-containing functionalized initiator. It is shown that changes in temperature or pH can change the conformation of the polymer surrounding the enzyme, which in turn enabled the rational tailoring of enzyme activity and stability. This method has afforded an increase in the activity and stability of the enzyme by an order of magnitude at pH's where the enzyme is usually inactive or unstable. Multimodal temperature responsive protein-block copolymer conjugates are described.

Abstract: The present invention provides amphiphilic diacetylene compounds, and compositions and self-assembled nanotubes containing the same. Also provided are methods of producing the compounds, compositions, and nanotubes of the invention, and methods of destroying or inhibiting the growth or proliferation of microorganisms using the nanotubes of the present invention.

Abstract: A method of applying a biocidal polymer to a surface including applying a solution of the biocidal polymer to the surface, wherein the biocidal polymer includes biocidal groups and the biocidal polymer is insoluble in water. The biocidal groups can be selected from the group consisting of quaternary salt groups or haloamino groups.

Abstract: The invention concerns the synthesis of nanotubes and nanocarpets by the spontaneous self-assembly of single chain achiral diacetylenes The monomer units may be cross-linked by UV irradiation to form stable supramolecular assemblies. The nanotubes of the invention, which are remarkably homogeneous in length and diameter, exhibit chromogenic and antibacterial properties.

Abstract: A process for culturing an immature ovarian follicle in vitro is disclosed. The process includes providing a culture having one or more immature ovarian follicles and providing a sufficient amount of oxygen to the ovarian culture on an intermittent basis, stepwise basis, or continuously, or combinations thereof, for a sufficient amount of time over the duration of the culture period to effect the maturation of the immature ovarian follicle. Over the course of the culture period, the oxygen concentration is raised until, at the end of the culture period, the oxygen concentration is in the range preferably between about 3% by volume (22.8 mmHg) and about 20% by volume (152 mmHg).